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Filtered Search Results
![Medchemexpress LLC Propanoic acid, 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]- | 1257063-35-6 | MFCD12406155 | 99.2% | 291.30 g·mol⁻¹ | C11H21N3O6 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000203479.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]- | 1257063-35-6 | MFCD12406155 | 99.2% | 291.30 g·mol⁻¹ | C11H21N3O6 | 50 MG
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Azido-PEG4-C2-acid is a PEG-based linker bearing an azide functional group for use in click chemistry and bioconjugation; it is supplied as a purified small-molecule research reagent.
- Azide-functional PEG4 linker for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Terminal carboxylic acid enables amide coupling and conjugation chemistry.
- High purity (99.2%) with molecular weight 291.30 g·mol⁻¹.
- CAS number 1257063-35-6 for unambiguous identification.
- Available in small quantities suitable for laboratory synthesis (50 mg).
- Store solid at -20 °C; in solution store at -80 °C for long-term stability.
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Medchemexpress LLC 2-Pyridinamine, 5,6-bis(4-methoxy-3-methylphenyl)- | 2306039-66-5 | 99.8% | C21H22N2O2 | 100 MG
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WSB1 Degrader 1 is a potent and orally active WSB1 (WD repeat and SOCS box-containing 1) degrader, exhibiting anticancer metastatic effects.
- Induces WSB1 degradation in H1299-WSB1 cells.
- Exhibits potent antimigration efficacy in KHOS and H460 cell lines.
- Significantly inhibits cancer cell migration under normoxia and hypoxia in KHOS cells.
- Elevates RhoGDI2 protein levels in KHOS cells under hypoxia.
- Significantly inhibits wound-healing of H1299-WSB1 cells.
- Blocks wound-healing capability of wild-type A2780 cells.
- Effectively inhibits pulmonary metastasis of cancer cells in mice bearing highly metastatic 4T1 breast cancer cells.
- Shows quick absorption and acceptable blood exposure in rats after oral or intraperitoneal dosing.
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Medchemexpress LLC Boc-N-PEG1-C2-NHS ester | 1260092-55-4 | 97.0% | C14H22N2O7 | 10 G
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Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
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Medchemexpress LLC Azido myristic acid | 80667-36-3 | MFCD00911365 | 98.4% | 241.33 g/mol | C12H23N3O2 | 25 MG
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Azido myristic acid (12-azidododecanoic acid) is an azide-containing fatty acid reagent used for click-chemistry labeling and detection of protein myristoylation. It reacts with alkyne-containing probes via copper-catalyzed azide-alkyne cycloaddition (CuAAC) and by strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO/BCN reagents, enabling metabolic labeling and enrichment of myristoylated proteins.
- Azide functional group for click chemistry applications.
- Suitable for metabolic labeling of myristoylated proteins.
- Reacts in CuAAC and SPAAC conjugation reactions.
- Supplied as a solid-liquid mixture with high purity.
- Stable when stored under recommended conditions (see datasheet for details).
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000784740 PYRROLIDIN-2-YL-ACET 25MG
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Medchemexpress LLC 2,6-Nonadienoic acid, 9-(3,3-dimethyl-2-oxiranyl)-3,7-dimethyl-, methyl-d3 ester, (2E,6E)- | 951116-89-5 | 2.5 MG
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Juvenile Hormone III-d3 is the deuterium labeled Juvenile Hormone III. Stable heavy isotopes like deuterium are incorporated into drug molecules as tracers for quantitation during drug development. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. This product is for research use only and has not been fully validated for medical applications.
- Deuterium labeled Juvenile Hormone III
- Used as tracer for quantitation during drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
- Molecular formula: C16H23D3O3
- Molecular weight: 269.39
- Appearance: Colorless to light yellow oil
- Purity (GC): 97.85%
- Isotopic enrichment: 99.6%
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Chemscene CHEMSCENE
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5000579973 1-BOC-2-CYANOPIPERIDINE 1G
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Ambeed AMBEED
5000849394 N-BOC-1 6-DIAMINOHEXANE 10G
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Medchemexpress LLC (Rac)-Razpipadon | 1643462-93-4 | 97.1% | C19H17F2N3O4 | 25 MG
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(Rac)-Razpipadon, also known as PW0464, is a nanomolar potent complete G protein biased ligand and a noncatechol D1R agonist. It exhibits agonist activity at D5R and wild-type human D1R in HEK293 cells and shows complete G protein bias without activity for D1R-mediated β-arrestin recruitment. This compound is intended for research use only.
- Nanomolar potent complete G protein biased ligand
- Noncatechol D1R agonist with EC50 of 5.8 nM (Gs-cAMP)
- Agonist activity at D5R (EC50 12 nM) and human D1R (EC50 5.3 nM) in HEK293 cells
- Exhibits complete G protein bias in vitro
- Appears as a white to off-white solid
- Soluble in DMSO at 25 mg/mL
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Medchemexpress LLC Boc-Aminooxy-PEG4-Tos | 1807539-01-0 | C20H33NO9S | 250 MG
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Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are innovative molecules that harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins by linking a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system for selective protein degradation
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Medchemexpress LLC Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]- | 1312309-63-9 | 99.88% | C7H13N3O4 | 250 MG
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Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Chemscene CHEMSCENE
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5000575679 4- TERT-BUTOXYCARBONYL AMIN 5G
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Medchemexpress LLC Boc-NH-PEG-amine (MW 5000) | ≥98.0% | 50 MG
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Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs utilize an intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase and a ligand for the target protein. This product is provided as a solid, white to off-white appearance, with a purity of ≥98.0%. It is intended for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system for selective protein degradation
- Solid, white to off-white appearance
- Purity of ≥98.0%
- Average molecular weight of 5000
- Stable under recommended storage conditions
- Available in various quantities for research
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Ambeed AMBEED
5000849748 1-BOC-3 5-DIMETHYL-PIPE 5G
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Aobchem AOBCHEM
5001091326 4-BROMOPHENYL PYRROLIDIN-1-Y
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