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Filtered Search Results
Medchemexpress LLC (3R,5S)-5-([1,1′-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone | 1038924-70-7 | 95.5% | C18H19NO | 100 MG
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This biological molecule, (3R,5S)-5-([1,1′-Biphenyl]-4-ylmethyl)-3-methyl-2-pyrrolidinone, is a white to light yellow solid intended for research use only.
- Purity: 95.5%
- Molecular weight: 265.35 g/mol
- Chemical formula: C18H19NO
- Appearance: Solid, white to light yellow
- Solubility in DMSO: 100 mg/mL (376.86 mM)
- Storage as powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC HY-B0032A 100mg Medchemexpress, Lurasidone CAS:367514-87-2 Purity:98%
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Medchemexpress,HY-B0032A 100mg Lurasidone CAS:367514-87-2 Formula:C28H36N4O2S Lurasidone is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone is also a partial agonist of 5-HT1A receptor with an IC50 of 6.75 nM. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC (S,R,S)-AHPC-propargyl | 2098799-78-9 | 99.5% | 526.65 | 50 MG
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(S,R,S)-AHPC-propargyl is a VHL ligand used in "click reactions" for PROTACs. It functions as a click chemistry reagent containing an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. VHL protein, a substrate recognition subunit of Cullin RING E3 ubiquitin ligase complexes, is frequently recruited by PROTACs to induce ubiquitination and subsequent proteasomal degradation of target proteins.
- VHL ligand for PROTACs.
- Click chemistry reagent with an alkyne group.
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc).
- Recruits VHL protein for ubiquitination and degradation of target proteins.
- Used in PROTAC synthesis.
- Applicable in cancer targeted therapy.
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Medchemexpress LLC 3'-Azido-3'-deoxyuridine | 70580-88-0 | C9H11N5O5 | 1 MG
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3'-Azido-3'-deoxyuridine | 70580-88-0 | C9H11N5O5 | 1 MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428778 1-METHYL-3-PYRROLIDI 10G
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eMolecules 1-BUTYLPYRROLIDIN-2-ONE 25G
5000216559 1-BUTYLPYRROLIDIN-2-ONE 25G
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Apexbio Technology LLC GW311616 hydrochloride 197890-44-1 5mg
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GW311616 hydrochloride (CAS 197890-44-1) is a selective cell-permeable inhibitor of human neutrophil elastase (HNE) exhibiting an IC50 of 22 nM and a Ki of 0 13 nM in enzymatic assays It demonstrates pronounced selectivity with IC50 values exceeding 100 M for trypsin cathepsin G and plasmin and greater than 3 M for chymotrypsin and tissue plasminogen activator In human whole blood assays GW311616 hydrochloride achieves an IC50 of 0 67 M The compound is orally bioavailable and displays prolonged activity in dog blood samples indicating a sustained inhibitory effect on neutrophil elastase GW311616 hydrochloride is valuable for investigating HNE s role in inflammation and related pathologies
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Cayman Chemical BIsIndolylmaleImIde III 5mg
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A protein kinase C inhibitor with structural similarity to staurosporine; inhibits PKCα (93% kinase activity inhibited at 1 μM ), PDK1 (IC50 =3.8 μM), S6K1, MAPKAP-K1, RSK2 and MSK1
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Chem-Impex International, Inc. N-Boc-3-pyrrolidinone | 101385-93-7 | MFCD01631194 | 5G
N-Boc-3-pyrrolidinone, 101385-93-7, MFCD01631194, 5G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428355 ICG MALEIMIDE 25MG
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Medchemexpress LLC Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) | 210344-98-2 | MFCD03490491 | >98.0% | 654.68 g/mol | C30H43FN4O11 | 50 MG
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Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a cell-permeable, selective caspase-8 inhibitor commonly used in apoptosis and caspase pathway research. It also exhibits activity against granzyme B and is supplied at research-scale purities suitable for in vitro studies.
- Selective and cell-permeable caspase-8 inhibitor.
- Also inhibits granzyme B, enabling broader apoptosis pathway studies.
- High purity (>98.0%) suitable for in vitro research applications.
- Available in multiple research-scale package sizes, including 50 MG.
- Peptide sequence: Z-Ile-Glu-Thr-Asp-FMK.
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Medchemexpress LLC 1-Boc-4-carboxymethyl piperazine | 156478-71-6 | 97.0% | C11H20N2O4 | 5 G
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1-Boc-4-carboxymethyl piperazine is a chemical compound that serves as a PROTAC linker, a crucial component in targeted protein degradation. This linker is specifically utilized in the synthesis of various PROTACs, including PROTAC IRAK4 degrader-12.
- Functions as a PROTAC linker
- Essential for the synthesis of PROTACs
- Exhibits 97.0% purity
- Appears as an off-white to gray solid
- Stable for 3 years at room temperature
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eMolecules TERT-BUTYL 3R-3-AMINOPYRR 5G
5000159619 TERT-BUTYL 3R-3-AMINOPYRR 5G
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Cell Signaling Technology CELL SIGNALING TECHNOLOGY INC
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5000587995 PAN-KERATIN C11 MOUSE MONOCLON
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000381428 AZIDO-PEG7-ACID 50MG
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