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Filtered Search Results
Medchemexpress LLC (E/Z)-Zotiraciclib | 937270-47-8 | C23H24N4O | 1 ML
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(E/Z)-Zotiraciclib is a potent inhibitor of CDK2, JAK2, and FLT3, with IC50s of 13, 73, and 56 nM, respectively. It effectively inhibits the proliferation of cancer cells and is intended for cancer research.
- Potent inhibitor of CDK2, JAK2, and FLT3
- Inhibits proliferation of cancer cells including HL-60, HCT-116, RAMOS, COLO205, and DU145
- Potently inhibits the CDK2 biomarker pRb in HCT-116 and MV4-11 cells
- Demonstrates significant tumor growth inhibition in HCT-116 colon cancer cell xenografts (82% TGI)
- Inhibits tumor growth in lymphoma Ramos cells xenografts (42% oral, 63% intraperitoneal TGI)
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eMolecules 2-CHLORO-1-PYRROLIDIN-1-Y 100G
5000224576 2-CHLORO-1-PYRROLIDIN-1-Y 100G
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eMolecules 2-CHLORO-1-PYRROLIDIN-1-Y 500G
5000224588 2-CHLORO-1-PYRROLIDIN-1-Y 500G
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eMolecules Broadpharm / DM1-SMCC / 1mg / 704981344 / BP-28008 / / 1228105-51-8 / [null] / 1072.620 / C51H66ClN5O16S
Broadpharm / DM1-SMCC / 1mg / 704981344 / BP-28008 / / 1228105-51-8 / [null] / 1072.620 / C51H66ClN5O16S
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eMolecules N-BOC-2- 2- 2-2-BROMOETHOX 5G
5000224499 N-BOC-2- 2- 2-2-BROMOETHOX 5G
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eMolecules 3S-TETRAHYDROFURAN-3-AM 2.5G
5000224424 3S-TETRAHYDROFURAN-3-AM 2.5G
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eMolecules 1-BOC-2 5-DIHYDRO-1H-PYRRO 10G
5000224368 1-BOC-2 5-DIHYDRO-1H-PYRRO 10G
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eMolecules 1S 4S-2-BOC-2 5-DIAZABIC 10G
5000224271 1S 4S-2-BOC-2 5-DIAZABIC 10G
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eMolecules Pharmablock / (3S)-tetrahydrofuran-3-amine / 25mg / 551186321 / PB00222 / 0.000 / 104530-79-2 / MFCD08234425 / 87.122 / C4H9NO
Pharmablock / (3S)-tetrahydrofuran-3-amine / 25mg / 551186321 / PB00222 / 0.000 / 104530-79-2 / MFCD08234425 / 87.122 / C4H9NO
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Medchemexpress LLC BOC-(1S,3R)-3-aminocyclopentanecarboxylic acid | 261165-05-3 | 229.27 | 10 G
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BOC-(1S,3R)-3-aminocyclopentanecarboxylic acid is a synthetic intermediate used in pharmaceutical synthesis.
- Useful for pharmaceutical synthesis
- Solid appearance
- White to off-white color
- For research use only
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Medchemexpress LLC TCO-PEG3-maleimide | 1809356-72-6 | C26H41N3O8 | 5 MG
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TCO-PEG3-maleimide is a click chemistry reagent that efficiently binds the TCO (trans-cyclooctene) moiety to thiol-containing molecules. This reagent is ideal for research applications involving antibodies and cysteine-containing peptides.
- Click chemistry reagent
- Binds TCO moiety to thiol-containing molecules
- Suitable for antibodies
- Suitable for cysteine-containing peptides
- For research use only
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Cayman Chemical BIsIndolylmaleImIde III 5mg
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A protein kinase C inhibitor with structural similarity to staurosporine; inhibits PKCα (93% kinase activity inhibited at 1 μM ), PDK1 (IC50 =3.8 μM), S6K1, MAPKAP-K1, RSK2 and MSK1
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eMolecules ETHYL 2-CYANO-4 4-DIMETHOXY 1G
5000224203 ETHYL 2-CYANO-4 4-DIMETHOXY 1G
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Medchemexpress LLC (rac)-AR-13503 (rac-AR-13324 M1 metabolite) | 1254032-16-0 | 99.1% | 321.37 g/mol | C19H19N3O2 | 25MG
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(rac)-AR-13503 (CAS 1254032-16-0) is a research small molecule described as the M1 metabolite of netarsudil. It functions as a ROCK and PKC inhibitor and has been reported to inhibit angiogenesis, increase retinal pigment epithelium permeability, and reduce aberrant neovascularization in oxygen-induced retinopathy models. Supplied in milligram-scale quantities for in vitro and in vivo research use.
- Inhibits Rho-associated kinases and protein kinase C.
- Demonstrated anti-angiogenic activity in retinal models.
- Enhances retinal pigment epithelium permeability.
- Suitable for pharmacology and ophthalmic research applications.
- Provided in milligram-scale packaging for research experiments.
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Medchemexpress LLC 2R 3S-E1R 50mg | 1424832-60-9 | 232.28 g/mol | C13H16N2O2 | 50 MG
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(2R,3S)-E1R is the (2R,3S) enantiomer of E1R and functions as a sigma-1 receptor positive allosteric modulator (Sig1R PAM) for preclinical research into cognition and memory disorders. Supplied as a powder for laboratory use (CAS 1424832-60-9; C13H16N2O2; MW 232.28 g/mol). For research use only.
- Solid powder, light yellow.
- CAS number 1424832-60-9.
- Molecular formula C13H16N2O2; molecular weight 232.28 g/mol.
- Storage: powder -20°C (3 years), 4°C (2 years); in solvent -80°C (6 months), -20°C (1 month).
- Reported purity ~98.8% (supplier specification).
- Intended for preclinical research; not for human or clinical use.
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