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Filtered Search Results
Medchemexpress LLC Maleimide-DOTA | 1006711-90-5 | 99.6% | 526.54 | C22H34N6O9 | 25 MG
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Maleimide-DOTA is a non-cleavable antibody-drug conjugate (ADC) linker that couples payloads to antibodies via maleimide chemistry for thiol-selective conjugation. Supplied for research use, it contains a DOTA chelator enabling radiolabeling and bioconjugation applications.
- Non-cleavable maleimide-based linker.
- DOTA chelator suitable for radiolabeling and metal coordination.
- High purity (approximately 99.6%).
- Soluble in DMSO and water; sonication recommended for dissolution.
- Examples of in vivo vehicle protocols provided by manufacturer for formulation.
- Store product at -20°C; in solvent, store at -80°C for long-term stability.
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Medchemexpress LLC (E/Z)-J147 | 1146963-51-0 | 99.5% | 350.34 | 1 ML
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(E/Z)-J147 is a potent, orally active, neuroprotective agent designed for cognitive enhancement. It readily crosses the blood-brain barrier and is being studied for its potential in treating Alzheimer's disease. The compound can inhibit monoamine oxidase B and the dopamine transporter, promoting cell survival.
- Exceptionally potent and orally active
- Neuroprotective agent for cognitive enhancement
- Readily crosses the blood-brain barrier
- Inhibits monoamine oxidase B (MAO B) and the dopamine transporter
- Promotes HT22 and primary cell survival
- Enhances memory and dendritic spine number in old mice
- Potential for Alzheimer's disease treatment
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Medchemexpress LLC OT-82 | 1800487-55-1 | 99.9% | 424.47 | 100 MG
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OT-82 is a potent, selective, and orally active inhibitor of NAMPT. It is selectively toxic to cells of hematopoietic origin and induces cell death in a NAD+ dependent manner, making it a promising antineoplastic agent for the study of hematological malignancies. This product is for research use only.
- Potent, selective, and orally active NAMPT inhibitor.
- Selectively toxic to cells of hematopoietic origin.
- Induces cell death in a NAD+ dependent manner.
- Promising antineoplastic agent for hematological malignancies.
- Exhibits hallmarks of apoptotic cell death.
- Inhibits recombinant NAMPT activity and reduces cellular NAD and ATP concentrations.
- Potently inhibited tumor growth in a multiple myeloma mouse model.
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Medchemexpress LLC HY-B0592 10mg Medchemexpress, Trandolapril CAS:87679-37-6 Purity:>98%
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Medchemexpress, HY-B0592 10mg Trandolapril CAS:87679-37-6 Trandolapril (RU44570) is a nonsulfhydryl prodrug that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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STA PHARMACEUTICAL US LLC DNA C(Bz) amidite | 100 g | CAS 102212-98-6 | MDL MFCD00036315
DNA C(Bz) amidite is a Amidite reagent (Subcategory: Cytosine Series) sold by WuXi TIDES. Offered in 100 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 102212-98-6
- MDL: MFCD00036315
- InChIKey: PGTNFMKLGRFZDX-SALLYJDFSA-N
- Molecular Weight: 833.922761998
- Molecular Formula: C46H52N5O8P
- Purity: ≥99%
- Container Type: 500 mL HDPE
- Pack Size: 100 g
- Net Weight: 100 g
- Gross Weight: 160.5 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1C[C@H](N2C(N=C(C=C2)NC(C3=CC=CC=C3)=O)=O)O[C@@H]1COC(C4=CC=C(C=C4)OC)(C5=CC=C(C=C5)OC)C6=CC=CC=C6)OCCC#N)C(C)C)C
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eMolecules EMOLECULES INC
5000841117 1-BOC-4-BROMOMETHYLPIPERID 1G
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Aobchem AOBCHEM
5000997067 3-FLUORO-2- HYDROXYMETHYL -6-
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Medchemexpress LLC J147 | 1807913-16-1 | 99.5% | 350.34 | 500 MG
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J147 is an exceptionally potent, orally active, neuroprotective agent designed for cognitive enhancement. It readily passes the blood-brain barrier (BBB) and exhibits inhibitory activity against monoamine oxidase B (MAO B) and the dopamine transporter. This compound holds potential for research into Alzheimer's disease (AD).
- Exceptionally potent and orally active
- Neuroprotective agent for cognitive enhancement
- Readily passes the blood-brain barrier
- Inhibits monoamine oxidase B
- Inhibits dopamine transporter
- Potential for Alzheimer's disease research
- Promotes HT22 and primary cell survival
- Enhances memory and dendritic spine number
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Chemscene CHEMSCENE
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5000575679 4- TERT-BUTOXYCARBONYL AMIN 5G
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Medchemexpress LLC Z-VDVAD-FMK | 210344-92-6 | ≥98.0% | 695.73 | 25 MG
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Z-VDVAD-FMK is a special inhibitor of caspase-2, observed to reduce Lovastatin-induced apoptosis. It significantly diminishes Lovastatin-induced DNA loss and inhibits Rho-kinase activity in HMEC-1 cells when stimulated by Thrombin.
- Inhibits caspase-2
- Reduces Lovastatin-induced apoptosis
- Prevents many morphological features of apoptosis in cotreatment with other caspase inhibitors
- Greatly inhibits Rho-kinase activity in HMEC-1 cells stimulated by Thrombin
- Significantly reduces Lovastatin-induced loss of DNA
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000702932 BR-PEG3-C2-BOC 500MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000702928 S R S-AHPC-BOC 500MG
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Medchemexpress LLC Z-IETD-AFC | 219138-02-0 | 99.7% | 821.75 | 5 MG
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Z-IETD-AFC is a specific fluorescence substrate designed to determine caspase-8 catalytic activity.
- Specific fluorescence substrate
- Determines caspase-8 catalytic activity
- Purity of 99.74%
- Molecular weight of 821.75
- Chemical formula: C37H42F3N5O13
- Appears as a white to off-white solid
- Emission wavelength: 500
- Excitation wavelength: 380
- Soluble in DMSO: ≥ 100 mg/mL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000702930 BOC-PEG2-I 500MG
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eMolecules 157688-46-5 | 2-(1-tert-butoxycarbonyl-4-piperidyl)acetic acid | Pharmablock | MFCD00800239 | 243.303 | C12H21NO4 | 97.000 | CC(C)(C)OC(=O)N1CCC(CC(O)=O)CC1 | 10g | 551059172
2-(1-tert-butoxycarbonyl-4-piperidyl)acetic acid | Pharmablock | 157688-46-5 | MFCD00800239 | 243.303 | C12H21NO4 | 97.000 | CC(C)(C)OC(=O)N1CCC(CC(O)=O)CC1 | 10g | 551059172
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