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Filtered Search Results
Medchemexpress LLC Rac-MGV354 | 1852495-86-3 | MFCD32664441 | 99.3% | 575.7 | C35H37N5O3 | 100 MG
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(Rac)-MGV354 is the racemic form of MGV354, a potent soluble guanylate cyclase (sGC) activator used in biochemical and cellular research. It demonstrates sub-nanomolar to low-nanomolar activity in cell assays and is used to study guanylate cyclase-mediated signaling.
- Potent sGC activation with EC50s of <0.5 nM (CHO) and 5 nM (GTM-3 E).
- Suitable for biochemical and cellular assays investigating cGMP signaling.
- Solid, white to off-white form with molecular weight 575.7 and formula C35H37N5O3.
- Storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC WSB1 Degrader 1 | 2306039-66-5 | MFCD34368539 | 99.8% | 334.41 g·mol⁻1 | C21H22N2O2 | 5 MG
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WSB1 Degrader 1 is a small-molecule research degrader that targets WSB1 (WD repeat and SOCS box-containing 1). It is described as potent and orally active with demonstrated anticancer and anti-metastatic effects, intended for biochemical, cellular, and early in vivo studies.
- Potent degrader of WSB1 with reported anticancer and anti-metastatic effects.
- Orally active in preclinical studies, suitable for in vivo research.
- High purity (99.81%), appropriate for sensitive assays.
- Good solubility in DMSO (25 mg/mL) and formulatable for in vivo use.
- Stable when stored as a powder under recommended conditions.
- Available in small research pack sizes for early-stage experiments.
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eMolecules 3S 5S 7S-ADAMANTANE-1-THI 1G
5000216437 3S 5S 7S-ADAMANTANE-1-THI 1G
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eMolecules 1-BOC-1-METHYLHYDRAZINE 1G
5000216356 1-BOC-1-METHYLHYDRAZINE 1G
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MEDCHEMEXPRESS LLC PF06650833 5MG
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501873781 PF06650833 5MG
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Medchemexpress LLC Z-VDVAD-FMK | 210344-92-6 | 98.0% | 695.73 | 1 MG
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Z-VDVAD-FMK is a special inhibitor of caspase-2 that produces a reduction in Lovastatin-induced apoptosis.
- Special inhibitor of caspase-2.
- Reduces lovastatin-induced apoptosis.
- Prevents many morphological features of apoptosis in cotreatment.
- Greatly inhibits Rho-kinase activity in HMEC-1 cells stimulated by thrombin.
- Significantly reduces lovastatin-induced loss of DNA.
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Medchemexpress LLC E/Z-mirin | 299953-00-7 | 99.2% | 220.25 g/mol | C10H8N2O2S | 1 ML
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E/Z-Mirin is a stereoisomeric mixture of (E)- and (Z)-mirin that inhibits the MRN (Mre11-Rad50-Nbs1) complex and prevents MRN-dependent ATM activation, used in research on DNA damage response and cell cycle signaling.
- Inhibits MRN complex and blocks MRN-dependent ATM activation
- Supplied as a 10 mM solution in DMSO and as solid quantities for flexible dosing
- High purity suitable for biochemical and cell-based assays
- Low molecular weight (220.25 g/mol) facilitates cellular studies
- SMILES provided for cheminformatics and compound registries
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Medchemexpress LLC (Z)-Indirubin | 906748-38-7 | 262.26 | 100 MG
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(Z)-Indirubin is an isomer of Indirubin, a bis-indole alkaloid that has demonstrated anticancer activity against chronic myelocytic leukemia. This product is intended for research use only.
- Isomer of indirubin
- Bis-indole alkaloid
- Exhibits anticancer activity against chronic myelocytic leukemia
- Suitable for research use
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000430836 Z -INDIRUBIN 1G
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Cayman Chemical 3 Z 6 Z 9 Z 12 Z 15 ZOctadeca
A microalgal PUFA; has been used as a chemotaxonomic biomarker for microalgae and dinoflagellates
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eMolecules ETHYL 2-CYANO-4 4-DIMETHOXY 1G
5000224203 ETHYL 2-CYANO-4 4-DIMETHOXY 1G
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Medchemexpress LLC Protac SGK3 degrader-1 | 2381320-35-8 | 99.9% | 1157.38 | C57H73FN10O11S2 | 10MG
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PROTAC SGK3 degrader-1 is a VHL-ligand-based proteolysis targeting chimera designed to induce degradation of Serum/Glucocorticoid Regulated Kinase 3 (SGK3) for biochemical and cell-based studies. The compound is supplied in small research pack sizes and is characterized by high analytical purity with supporting RP-HPLC documentation.
- VHL-ligand-based PROTAC design for targeted protein degradation.
- Efficient degradation of SGK3 in cell-based assays.
- High purity suitable for research applications.
- Available in small pack sizes for assay development.
- Supported by RP-HPLC analytical documentation.
- Validated for use in cell viability and western blot analyses.
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eMolecules BOC--TRANS-4-PHENYLPYRRO 1G
5000216072 BOC--TRANS-4-PHENYLPYRRO 1G
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Medchemexpress LLC Z-3578 | 473687-20-6 | 98.72% | 467.37 | 25 MG
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Z-3578 is an orally active small-molecule antagonist of MrgX2 with potent antipseudoallergic activity. It effectively inhibits mast cell degranulation and can be used for the study of pseudoallergic reactions.
- Inhibits mast cell degranulation induced by substance P and C48/80
- Suppresses the release of β-hexosaminidase
- Significantly reduces the release of histamine and TNF-α
- Decreases intracellular calcium flux
- Alleviates paw swelling and dye extravasation in a mouse pseudoallergy model
- Reduces serum histamine levels in a mouse pseudoallergy model
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eMolecules 1-BOC-3-AMINOMETHYLAZETIDIN 1G
5000216984 1-BOC-3-AMINOMETHYLAZETIDIN 1G
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