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Z-VAD-FMK is a pan-caspase inhibitor and an ICE-like protease inhibitor. It inhibits apoptosis by preventing the processing of CPP32 to its active form and limits cryopreservation-induced apoptosis by reducing caspase-3 activity in in vitro produced bovine embryos. It is immunosuppressive in vitro, inhibiting T cell proliferation, and can be used for the study of acute pancreatitis.
Pan-caspase and ICE-like protease inhibitor
Inhibits apoptosis
Reduces caspase-3 activity
Immunosuppressive in vitro, inhibiting T cell proliferation
Can be used for the study of acute pancreatitis
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More