Quinolines and derivatives
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Filtered Search Results
Sigma Aldrich Fine Chemicals Biosciences 8-Hydroxyquinoline crystalline | 148-24-3 | MFCD00006807 | 25G
8-Hydroxyquinoline crystalline | Purity: 98.5-101.5% | Mol Wt: 145.16 | 148-24-3 | MFCD00006807 | 25G
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Accela Chembio Inc 2 | 8-quinolinediol | 25g | 15450-76-7 | MFCD00216696 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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2 | 8-quinolinediol | 25g | 15450-76-7 | MFCD00216696 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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Medchemexpress LLC EthD bromide | 1239-45-8 | 99.27% | 250 MG
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EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis. It binds to DNA for visualization under UV light.
- Fluorescent tag for nucleic acids
- Intercalating agent
- Used for agarose gel electrophoresis
- Used in studies to reduce mitochondrial DNA copy number
- Used in Western blot analysis of proteins in the cGAS-STING pathway
- Visualizes EtBr uptake via hemichannels in astrocytes
- Targets DNA for staining
- Involves the cell cycle/DNA damage pathway
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Medchemexpress LLC Ethidium bromide | 1239-45-8 | MFCD00011724 | 99.4% | 100 MG
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EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis. It is for research use only and not sold to patients. It binds to DNA, allowing visualization under ultraviolet (UV) light.
- Serves as a fluorescent tag (nucleic acid stain)
- Used in molecular biology laboratories for techniques such as agarose gel electrophoresis
- Binds to DNA
- Allows visualization under ultraviolet (UV) light
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Boston Bioproducts Inc Ethidium Bromide (10 mg/ml) - 10ml
Ethidium Bromide (10 mg/ml) - 10ml (For Research Use and Further Manufacturing Only)
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Medchemexpress LLC ACT-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 1 MG
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ACT-1004-1239 is a potent, selective, orally active CXCR7 antagonist with an IC50 value of 3.2 nM. It is intended for research use only.
- Inhibits human, dog, rat, mouse, guinea pig, macaque CXCR7 with IC50s of 3.2, 2.3, 3.1, 2.3, 0.6, 1.5 nM respectively.
- Promotes oligodendrocyte precursor cell (OPC) differentiation by increasing CXCL12 levels.
- Increases plasma CXCL12 concentration in naive male DBA/1 mice.
- Reduces disease severity in MOG-induced experimental autoimmune encephalomyelitis (EAE) model.
- Increases myelination in the Cuprizone-induced demyelination model mice.
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Medchemexpress LLC ACT-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 50 MG
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ACT-1004-1239 is a potent, selective, and orally active CXCR7 antagonist with an IC50 value of 3.2 nM. It promotes oligodendrocyte precursor cell (OPC) differentiation by increasing CXCL12 levels. In animal models, it has been shown to reduce disease severity in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) and increase myelination in Cuprizone-induced demyelination models. This product is for research use only.
- Potent, selective, and orally active CXCR7 antagonist
- IC50 value of 3.2 nM
- Promotes oligodendrocyte precursor cell (OPC) differentiation
- Increases CXCL12 levels
- Reduces disease severity in MOG-induced experimental autoimmune encephalomyelitis (EAE) in animal models
- Increases myelination in Cuprizone-induced demyelination models
- For research use only
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AdipoGen Ethidium bromide Solution
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Chemical. CAS 1239-45-8. Formula C21H20BrN3. MW 394.31. Synthetic. Ethidium bromide EtBr is the most commonly used nucleic acid stain for PAGE or agarose gel electrophoresis. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA and 25-fold on binding double-stranded DNA so that destaining the background is not necessary with a low stain concentration 10 µg/ml. Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids. Ethidium bromide intercalates double-stranded DNA and RNA and acts as a frameshift mutagen. It confers a deep red stain to DNA by acting as an intercalating agent between the starch bases. It has been shown to bind to single-stranded DNA although not as strongly and triple-stranded DNA. Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. It can be used in conjunction with acridine orange to differentiate between viable, apoptotic and necrotic cells.
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![Medchemexpress LLC 3-piperidinecarboxamide, 1-(cyclopropylmethyl)-4-[[[5-(2,4-difluorophenyl)-3-isoxazolyl]carbonyl]am | 2178049-58-4 | 98.8% | 522.55 | C27H28F2N6O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000221277.png-250.jpg)
Medchemexpress LLC 3-piperidinecarboxamide, 1-(cyclopropylmethyl)-4-[[[5-(2,4-difluorophenyl)-3-isoxazolyl]carbonyl]am | 2178049-58-4 | 98.8% | 522.55 | C27H28F2N6O3 | 5 MG
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ACT-1004-1239 is a potent, selective, orally active CXCR7 (ACKR3) antagonist supplied for research use. It shows nanomolar potency in biochemical assays and has demonstrated target engagement and pharmacological effects in preclinical models, including modulation of CXCL12/CXCL11 signaling and efficacy in rodent disease models. Supplied formats support both in vitro and in vivo study designs.
- Potent CXCR7 antagonism with reported IC50 of 3.2 nM.
- High purity suitable for research applications.
- Available as solid and 10 mM DMSO solution for convenient use.
- Appropriate for in vitro and in vivo pharmacology studies.
- For research use only; not for human or veterinary use.
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Apexbio Technology LLC Ethidium bromide 1239-45-8 250mg
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Ethidium bromide (CAS 1239-45-8) is a small-molecule fluorescent dye widely utilized in molecular biology for nucleic acid visualization It intercalates between the base pairs of double-stranded DNA or RNA resulting in enhanced fluorescence upon binding With an excitation spectrum between 300 360 nm and an emission maximum at 590 nm ethidium bromide is commonly used to stain nucleic acids during agarose gel electrophoresis This property facilitates the detection and analysis of DNA and RNA in applications such as gene expression studies and nucleic acid quantification supporting a broad range of experimental workflows in genomics and molecular diagnostics
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000428186 ACRIDINE ORANGE 10-N 5MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431375 ACRIDINE ORANGE 10-N 50MG
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eMolecules Proflavine hemisulfate hydrate | 1811-28-5 | MFCD00149650 | 1g
Combi-Blocks | Proflavine hemisulfate hydrate | 1g | 517032039 | QC-3763 | 95.000 | 1811-28-5 | MFCD00149650 | 534.590 | C26H26N6O5S
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Medchemexpress LLC Acridine orange base | 494-38-2 | 96.58% | 100 MG
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Acridine Orange base is a cell-permeable fluorescent dye utilized for staining various organisms such as bacteria, parasites, and viruses a bright orange. When applied under specific conditions (pH=3.5, Ex=460 nm), it allows for the distinction of human cells, which appear green, through fluorescence microscopy. This dye exhibits green fluorescence when bound to double-stranded DNA (dsDNA) and red fluorescence when bound to single-stranded DNA (ssDNA) or single-stranded RNA (ssRNA), making it suitable for cell cycle assays.
- Cell-permeable fluorescent dye.
- Stains organisms bright orange.
- Distinguishes human cells in green.
- Fluoresces green with dsDNA.
- Fluoresces red with ssDNA or ssRNA.
- Useful for cell cycle assays.
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AdipoGen Quinine anhydrous
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Chemical. CAS 130-95-0. Formula C20H24N2O2. MW 324.42. Synthetic. Because of its relatively constant and well-known fluorescence quantum yield, quinine is also used in photochemistry as a common fluorescence standard. It has been used for imaging of oxygen evolution and oxide formation. Chloride and bromide have been shown to quench fluorescence. Generally it is famous as potassium channel blocker with antipyretic fever-reducing, antimalarial, analgesic painkilling, and anti-inflammatory properties.
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