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Filtered Search Results
Medchemexpress LLC IL-31 Cynomolgus H 50ug | 50ug
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IL-31 is a multifunctional cytokine that activates STAT3 through IL-31 heterodimeric receptors (IL31RA and OSMR) and may activate STAT1 and STAT5 IL-31 is known for its involvement in skin immunity where it regulates immune responses IL-31 Protein Cynomolgus (HEK293 His) is the recombinant cynomolgus-derived IL-31 protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC 4-((3-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyl)oxy | 1092369-24-8 | MFCD31631580 | 99.6% | 624.72 g·mol⁻¹ | C34H44N2O9 | 50 MG
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SLF-amido-C2-COOH is a synthetic FKBP12-binding ligand used as a PROTAC building block. It couples an SLF recognition motif to a short linker ending in a carboxylic acid, providing a convenient functional handle for conjugation in bifunctional degrader synthesis.
- Acts as an FKBP12-binding moiety for PROTAC construction.
- Provides a carboxylic acid handle for amide or ester coupling.
- Compatible with standard small-molecule coupling chemistries.
- High purity suitable for research applications (≈99.6%).
- Molecular formula C34H44N2O9; molecular weight 624.72 g·mol⁻¹.
- Supplied as an off-white to white solid for synthetic use.
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eMolecules 7-Methoxy-4(1H)-quinolinone | 82121-05-9 | 1G
Chem-Impex | 7-Methoxy-4(1H)-quinolinone | 1G | 82121-05-9 | MFCD07369800 | MW:172.57
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eMolecules Building Block Tool
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Medchemexpress LLC Al-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 10MG
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AL-611 is a research-grade small-molecule inhibitor described by the manufacturer as an HCV protease inhibitor intended for laboratory research use. It is supplied as a white to off-white solid and is characterized by a high reported purity and defined molecular properties.
- Potent HCV protease inhibitor for laboratory research.
- High purity (99.93%).
- White to off-white solid, suitable for analytical and biological assays.
- Molecular weight 614.54 Da; molecular formula C25H33F2N6O8P.
- Datasheet, certificate of analysis, and safety data sheet available.
- Intended for research use only, not for human or veterinary use.
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TARGETMOL CHEMICALS INC KRM-III 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation with an IC50 of approximately 5 uM. purity: 99%
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eMolecules Ambeed 3 4-Dimethoxy-2-nitrobenzoic acid 100mg 525226340 A578526 0 000 79025-28-8 MFCD00074884 227 172 C9H9NO6
Ambeed 3 4-Dimethoxy-2-nitrobenzoic acid 100mg 525226340 A578526 0 000 79025-28-8 MFCD00074884 227 172 C9H9NO6
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![Apexbio Technology LLC parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096693.png-250.jpg)
Apexbio Technology LLC parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] 25mg
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Parathyroid hormone (7-34) is a polypeptide antagonist targeting parathyroid hormone receptors (PTH1R and PTH2R) It is derived from Homo sapiens and Macaca fascicularis and is designed to modulate PTH receptor activity thereby influencing calcium and phosphate homeostasis Parathyroid hormone (7-34) exerts its biological activity primarily through competitive interaction with PTH receptors affecting absorption processes in bone kidney and intestinal tissues Based on these pharmacological properties parathyroid hormone (7-34) holds research potential in studies of mineral metabolism bone remodeling and calcium-phosphate balance disorders
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Ambeed Benzofuran2 3H one
Benzofuran-2(3H)-one, 553-86-6, 98%
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Ambeed S 4 9HFluoren9yl methoxy c
(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%
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Medchemexpress LLC Bay 59-3074 100Mg | HY-100488-100MG
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Bay 59-3074 100Mg
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Medchemexpress LLC MTI-31 | 1567915-38-1 | 100.0% | 474.55 | C26H30N6O3 | 1MG
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MTI-31 (LXI-15029) is a potent, orally active, and highly selective inhibitor of mTORC1 and mTORC2 used in preclinical cancer research. It demonstrates strong biochemical potency and in vivo efficacy in tumor models, with formulation and storage guidance for laboratory use.
- Potent, selective inhibition of mTORC1 and mTORC2.
- High binding affinity for mTOR (Kd 0.20 nM) and low biochemical IC50 (39 nM).
- High purity and consistent solid appearance for reproducible results.
- Soluble in DMSO and compatible with common in vivo formulations.
- Stable as powder at low temperatures and in solvent with recommended storage conditions.
- Molecular formula C26H30N6O3 and molecular weight 474.55.
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Medchemexpress LLC LM11A-31 10mM 1mL | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 1 ML
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LM11A-31 a non-peptide p75NTR (neurotrophin receptor p75) modulator is an orally active and potent proNGF (nerve growth factor) antagonist LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer s disease mouse models with mid- to late-stage disease progression[1][2]
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TARGETMOL CHEMICALS INC MTI-31 1MG
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Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.MTI-31 (LXI-15029) is a potent, orally active, and highly selective inhibitor of mTORC1 and mTORC2, exhibiting a Kd of 0.20 nM for mTOR and >5,000-fold selectivity over PIK3CA, PIK3CB, and PIK3G in binding assays, with an IC50 of 39 nM for mTOR in a LANCE assay of mTOR substrate phosphorylation with 100 uM ATP [1]. Purity 99.76%
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Ambeed tertButyl 1 8diazaspiro 4.5 de
tert-Butyl 1,8-diazaspiro[4.5]decane-8-carboxylate, 937729-06-1, 95%
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Apexbio Technology LLC 17-AAG (KOS953) 75747-14-7 200mg
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17-AAG (KOS953) is a synthetic derivative of geldanamycin that inhibits heat shock protein 90 (HSP90) It acts by binding to HSP90 causing destabilization of client proteins including HER2 Raf-1 p53 and components of MAPK signaling pathways Reported IC50 for 17-AAG in BT474 cells is approximately 6 nM Its biological activity has been investigated broadly including in multiple myeloma breast cancer thyroid cancer Hodgkin lymphoma and melanoma cellular models Ongoing studies explore 17-AAG both as monotherapy and in combination with agents like bortezomib or trastuzumab for addressing treatment-resistant cancer cell lines Currently 17-AAG is evaluated in Phase II clinical trials
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