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Filtered Search Results
Medchemexpress LLC Dihydralazine sulfate | 7327-87-9 | 10 MG
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Dihydralazine sulfate is a vasodilator and an antihypertensive agent for research applications.
- Purity: 98.0%
- Molecular weight: 288.28
- Molecular formula: C8H12N6O4S
- Appearance: Solid
- Color: Off-white to light yellow
- Soluble in DMSO (4.17 mg/mL)
- Insoluble in water (< 0.1 mg/mL)
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Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 100 MG
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5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active, non-competitive 20S proteasome inhibitor. It has the ability to inhibit NF-κB activity and induce the death of cancer cells, while exhibiting low cytotoxicity towards normal hematopoietic cells. This compound can be utilized for research related to cancer, particularly leukemia.
- Orally active.
- Functions as a non-competitive 20S proteasome inhibitor.
- Inhibits NF-κB activity.
- Induces cancer cell death.
- Shows low cytotoxicity towards normal hematopoietic cells.
- Can be used for cancer research, including leukemia.
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Medchemexpress LLC Tigecycline | 220620-09-7 | 99.95% | 200 MG
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Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. It has been shown to inhibit AML2 and HL-60 cells, with specific IC50 values. Its activity extends to bacterial strains, demonstrating a mean inhibitory concentration (MIC) of approximately 125 ng/mL for E. coli (MG1655 strain), and MIC50 and MIC90 values of 1 and 2 mg/L, respectively, for Acinetobacter baumannii.
- Broad-spectrum glycylcycline antibiotic
- Inhibits AML2 and HL-60 cells in vitro
- Demonstrates activity against E. coli and Acinetobacter baumannii
- Light yellow to orange solid appearance
- Derived from microorganisms
- Reduced tumor volume and weight in an AML xenograft model
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000664632 CFM 1571 HYDROCHLOR 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000665365 INFLUENZA HA 307-31 25MG
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Medchemexpress LLC Cinchonine | 118-10-5 | MFCD00064372 | 99.7% | 294.39 | C19H22N2O | 25g
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Cinchonine is a natural compound present in Cinchona bark with antimalarial antitumor anti-inflammatory anti platelet-aggregation and anti-obesity properties Cinchonine inhibits cells proliferation and autophagy and induces apoptosis through activation of Caspase-3 Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells[1]
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000586088 TRICLABENDAZOLE 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000665353 TNF-A 31-45 HUMAN 1MG
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Apexbio Technology LLC Carboplatin 41575-94-4 200mg
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Carboplatin (CAS 41575-94-4) is a small molecule inhibitor of DNA synthesis It exerts its antiproliferative activity by binding to DNA thereby hindering DNA synthesis and impairing DNA repair pathways In cell proliferation assays carboplatin inhibits growth of human ovarian carcinoma cell lines A2780 SKOV-3 IGROV-1 and HX62 with IC50 values of 6 2 12 4 2 2 and 116 M respectively Carboplatin shows antiproliferative effects on lung cancer cell lines UMC-11 H727 and H835 and demonstrates antitumor activity in xenograft mouse models Carboplatin is commonly used in preclinical oncology research
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![eMolecules 680596-79-6 | 1,4-Dioxaspiro[4.5]-7-decene-8-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | MFCD04115656 | 266.140 | C14H23BO4 | 98.000 | CC1(C)OB(OC1(C)C)C1=CCC2(CC1)OCCO2 | 25g | 444748645](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000473335.jpg-250.jpg)
eMolecules 680596-79-6 | 1,4-Dioxaspiro[4.5]-7-decene-8-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | MFCD04115656 | 266.140 | C14H23BO4 | 98.000 | CC1(C)OB(OC1(C)C)C1=CCC2(CC1)OCCO2 | 25g | 444748645
1,4-Dioxaspiro[4.5]-7-decene-8-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | 680596-79-6 | MFCD04115656 | 266.140 | C14H23BO4 | 98.000 | CC1(C)OB(OC1(C)C)C1=CCC2(CC1)OCCO2 | 25g | 444748645
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000586673 DIHYDROETHIDIUM SOL 500UL
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Medchemexpress LLC Sevabertinib (BAY 2927088) | 2521285-05-0 | 99.9% | 484.93 | 200 MG
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Sevabertinib (BAY 2927088) is an orally active and reversible dual EGFR-HER2 inhibitor with potent anticancer activity against lung cancer. It shows significantly reduced activity against HER4.
- Orally active and reversible dual EGFR-HER2 inhibitor
- Exhibits anticancer activity against lung cancer
- Potently inhibits proliferation of isogenic Ba/F3 cells ectopically expressing HER2 exon 20 insertions
- Potently inhibits proliferation of isogenic Ba/F3 cells activating HER2 point mutations or putative secondary acquired resistance mutations
- Inhibits proliferation of lung cancer cell lines NCI-H1781 and NCI-H2170
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Medchemexpress LLC Argatroban monohydrate | 141396-28-3 | MFCD23102419 | 99.6% | 1 ML
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Argatroban monohydrate is a direct, selective thrombin inhibitor. It may also have a complementary effect for preventing thrombus formation without aggravating bleeding tendency due to its monotarget specificity to thrombin.
- Administration (0.5 to 2 micrograms/kg/min) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries.
- Appears to enhance reperfusion with TPA in patients with AMI, particularly in those with delayed presentation, and was associated with lower incidences of major bleeding and adverse clinical outcomes compared to heparin.
- Suitable for creating animal models for thrombolysis.
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Medchemexpress LLC (S,R,S)-AHPC-amido-C5-acid | 2162120-87-6 | >99.5% | 25 MG
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(S,R,S)-AHPC-amido-C5-acid is a laboratory chemical identified by CAS number 2162120-87-6. It is supplied as a solid and exhibits chemical stability under recommended storage conditions, making it suitable for various research applications.
- Stable under recommended storage conditions.
- Solid appearance.
- Suitable for laboratory chemical applications.
- Recommended storage at -20°C, sealed, away from moisture and light.
- Shipping at room temperature if less than two weeks.
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Medchemexpress LLC Isavuconazole | 241479-67-4 | 99.9% | C22H17F2N5OS | 200 MG
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Isavuconazole is a triazole proagent that exhibits antifungal activity against yeasts, molds, and dimorphic fungi. It functions by inhibiting ergosterol biosynthesis, which leads to the disruption of the fungal membrane structure and function. Isavuconazole is also identified as a moderate inhibitor of CYP3A4.
- Triazole proagent
- Exhibits antifungal activity against yeasts, molds, and dimorphic fungi
- Inhibits ergosterol biosynthesis
- Disrupts fungal membrane structure and function
- Moderate inhibitor of CYP3A4
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