Quinolines and derivatives
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Filtered Search Results
Apexbio Technology LLC Ganetespib (STA-9090)(Synonyms: STA-9090, Ganetespib, STA9090, STA 9090), 200mg, CAS: 888216-25-9.
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Ganetespib (STA-9090 CAS 888216-25-9) is a small-molecule inhibitor targeting heat shock protein 90 (Hsp90) It binds competitively to the ATP-binding pocket located at the N-terminal region of Hsp90 disrupting its chaperone activity and subsequently causing degradation of client proteins involved in tumor growth and survival Structurally distinct from geldanamycin-derived inhibitors Ganetespib features a triazolone moiety Preclinical studies have demonstrated antitumor activity across various cancer cell types including lung prostate colon breast cancers melanoma and leukemia highlighting its therapeutic potential for cancer research
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Medchemexpress LLC Imiquimod (maleate) | 896106-16-4 | 99.9% | 500 MG
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Imiquimod maleate (R 837 maleate) is an immune response modifier and a selective toll-like receptor 7 (TLR7) agonist. It demonstrates antiviral and antitumor effects in vivo. This product is an analytical standard intended for research and analytical applications, and can be used for research of external genital, perianal warts, cancer, and COVID-19, and to induce psoriasis models.
- Selective toll-like receptor 7 (TLR7) agonist
- Exhibits antiviral and antitumor effects in vivo
- Suitable for research of external genital, perianal warts, cancer, and COVID-19
- Can be used to induce psoriasis models
- Targets TLR7 and HSV-1
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eMolecules 1056942-37-0 | 1-Bromo-4-chloro-2-(difluoromethoxy)benzene | MFCD14698391 | 250mg
ChemScene | 68-Difluorothiochroman-4-one | 100mg | 569146754 | CS-0131579 | 1097779-72-0 | MFCD11642634 | 200.200 | C9H6F2OS
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Medchemexpress LLC Quin C1 | 786706-21-6 | 98.5% | 445.51 g/mol | C26H27N3O4 | 5 MG
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Quin C1 is a small-molecule agonist of formyl peptide receptor 2 (FPR2/ALX) used in laboratory research to study inflammatory signaling. It is supplied as a high-purity solid intended for in vitro and in vivo experiments, with recommended cold-chain storage for long-term stability.
- Small-molecule FPR2/ALX agonist for modulation of inflammatory responses.
- High purity suitable for biochemical and cellular assays.
- Supplied as a powder with recommended cold storage to preserve stability.
- Available in multiple milligram pack sizes for experimental flexibility.
- Includes datasheet, certificate of analysis, and safety data for reproducible use.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000743628 CYANINE7.5 AMINE 5MG
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Medchemexpress LLC Act-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 10MG
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ACT-1004-1239 is a potent, selective, orally available CXCR7 (ACKR3) antagonist developed as a first-in-class compound. It exhibits low nanomolar potency and has shown immunomodulatory and promyelinating effects in preclinical models and early clinical research.
- Potent CXCR7 antagonism with IC50 3.2 nM.
- Orally bioavailable compound suitable for systemic dosing.
- Demonstrated immunomodulatory and promyelinating activity in vivo.
- High chemical purity and solid, stable formulation for storage.
- Compatible with in vitro and in vivo pharmacology studies.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000738997 CPPD-Q 5MG
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Medchemexpress LLC Panobinostat | 404950-80-7 | MFCD09833242 | 99.4% | 349.43 | C21H23N3O2 | 200 MG
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Panobinostat is a potent, orally active, non-selective histone deacetylase (HDAC) inhibitor supplied as a research-grade powder for laboratory use. It exhibits antineoplastic activity and is commonly used in epigenetic and cancer research, and in studies of apoptosis and autophagy. Not for human or veterinary use.
- Potent non-selective HDAC inhibitor with antineoplastic activity.
- High purity (99.4% by LCMS).
- Powder form, soluble in DMSO ≥ 100 mg/mL.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (1 year).
- Used in studies of apoptosis, autophagy, and cancer cell proliferation.
- Intended for research use only; not for human or veterinary use.
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eMolecules 72716-87-1 | 2-methoxypyridine-4-carbaldehyde | Pharmablock | MFCD06410680 | 137.138 | C7H7NO2 | 97.000 | COc1cc(C=O)ccn1 | 25mg | 551201750
2-methoxypyridine-4-carbaldehyde | Pharmablock | 72716-87-1 | MFCD06410680 | 137.138 | C7H7NO2 | 97.000 | COc1cc(C=O)ccn1 | 25mg | 551201750
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Selleck Chemical LLC HOIPIN-8-E1798-5MG
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HOIPIN-8 is a potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) and NF- B signaling with an IC50 value of 11 nM It serves as a powerful tool for investigating the physiological and cellular functions of LUBAC
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Apexbio Technology LLC Tempo 2564-83-2 200mg
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Tempo (CAS 2564-83-2) is a stable nitroxide radical widely employed in biomedical research for its redox-active properties It facilitates the dismutation of superoxide radicals thereby modulating mitochondrial reactive oxygen species (ROS) levels and influencing cellular oxidative stress responses Tempo also serves as an oxidation catalyst particularly in the transformation of primary alcohols to aldehydes Studies indicate that Tempo exerts both antioxidant and mutagenic effects inducing DNA strand breaks and displaying cytotoxic and mutagenic activities in in vitro models such as murine lymphoma cells It is utilized for investigating oxidative stress redox regulation and chemical mutagenesis
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Medchemexpress LLC (Ser8)-GLP-1 (7-36) amide, human | 215777-46-1 | 99.1% | 3313.63 | 50 MG
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(Ser8)-GLP-1 (7-36) amide, human is a glucagon-like peptide 1 amide derived from glucagonogen. It is a cleavage product of the GLP-1 (1-36) amide peptide. This compound acts as an entero-insulinotropic hormone, which means it stimulates the release of insulin from pancreatic β-cells in a glucose-dependent manner. Additionally, it influences gastrointestinal motility and secretion. The product is intended for research purposes only and is not for sale to patients.
- Derived from glucagonogen, a cleavage product of GLP-1 (1-36) amide peptide.
- Functions as an entero-insulinotropic hormone.
- Induces glucose-dependent insulin release from pancreatic β-cells.
- Affects gastrointestinal motility and secretion.
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Medchemexpress LLC SARS-CoV-2-IN-86 | 368866-07-3 | MFCD02683117 | 99.4% | 466.53 | C26H30N2O6 | 1 G
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SARS-CoV-2-IN-86 is a small-molecule research compound that inhibits SARS-CoV-2 methyltransferases (nsp14 and nsp16) and is reported as an andrographolide derivative. It is supplied as a solid or as a 10 mM solution in DMSO for in vitro antiviral and enzymatic studies. Batch-specific certificates of analysis and safety documentation are available from the supplier.
- Inhibits SARS-CoV-2 methyltransferases (nsp14 and nsp16).
- Andrographolide derivative for antiviral research.
- Available as solid and 10 mM solution in DMSO.
- High purity (≈99.4%) per supplier documentation.
- Suitable for in vitro enzymatic and antiviral assays.
- Powder stable at -20°C; solvent storage guidelines available.
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Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyluridine | 103285-22-9 | MFCD00274123 | 98.0% | 560.59 | C31H32N2O8 | 5 G
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5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine is a DMT-protected uridine analog used as a nucleoside building block and intermediate for the synthesis of modified oligonucleotides. It is supplied as a light-yellow solid with defined purity and storage specifications suited for research and preparative oligonucleotide chemistry.
- DMT protected at the 5' hydroxyl for selective chain assembly.
- 2'-O-methyl modification supports increased nuclease resistance in oligonucleotides.
- High purity material suitable for synthesis and analytical workflows.
- Available in gram-scale pack sizes to accommodate different synthesis scales.
- Stable under recommended storage conditions to preserve quality over time.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000743136 1 4 7-TRIAZONANE 5G
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