Quinolines and derivatives
Apexbio Technology LLC IAA-94 54197-31-8 5mg
IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
Apexbio Technology LLC IAA-94 54197-31-8 25mg
IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
Apexbio Technology LLC IAA-94 54197-31-8 10mg
IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
Medchemexpress LLC Desonide | 638-94-8 | 99.2% | 200 MG
Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on the glucocorticoid receptor. It can also specifically bind to the mutant huntingtin protein (mHTT), reducing the level and toxicity of mHTT. Desonide can be used in the research of Huntington's disease and inflammatory diseases such as atopic dermatitis.
- Non-fluorinated corticosteroid anti-inflammatory agent
- Modulates glucocorticoid receptor activity
- Specifically binds to mutant huntingtin protein (mHTT)
- Reduces mutant huntingtin protein (mHTT) levels and toxicity
- Used in Huntington's disease research
- Used in inflammatory disease research, such as atopic dermatitis
- Inhibits mHTT-induced cytotoxicity
- Reduces apoptotic signals and improves cell survival
- Demonstrates therapeutic effects in Huntington's disease mouse models
- Rescues behavioral deficits and lowers mHTT aggregates