Tetrahydroisoquinolines
![Medchemexpress LLC [3-[[4-(1,1-dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone | 1380548-02-6 | 99.2% | 465.58 g/mol | C31H31NO3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000228023.png-250.jpg)
Medchemexpress LLC [3-[[4-(1,1-dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone | 1380548-02-6 | 99.2% | 465.58 g/mol | C31H31NO3 | 10 MG
SR10067 is a potent, selective, brain-penetrant REV-ERB agonist used in research on metabolic and neuropsychiatric disorders. It exhibits high affinity for Rev-Erbβ and Rev-Erbα with reported IC50 values of 160 nM and 170 nM, respectively, and is supplied as a high-purity research-grade small molecule.
- Potent Rev-Erbα/β agonist (IC50 170 nM and 160 nM).
- Brain-penetrant, suitable for in vivo research applications.
- High purity (approximately 99.2%) for reproducible results.
- Available in multiple pack sizes, including 10 mg.
- Molecular weight 465.58 g/mol; formula C31H31NO3.
- CAS 1380548-02-6 for unambiguous identification.
eMolecules 30798-64-2 | 1,2,3,4-Tetrahydroisoquinolin-7-ol | Combi-Blocks | MFCD08234812 | 149.193 | C9H11NO | 96.000 | Oc1ccc2CCNCc2c1 | 1g | 495743251
1,2,3,4-Tetrahydroisoquinolin-7-ol | Combi-Blocks | 30798-64-2 | MFCD08234812 | 149.193 | C9H11NO | 96.000 | Oc1ccc2CCNCc2c1 | 1g | 495743251
eMolecules 1313367-56-4 | Medchem Express | NVP-CGM097 (sulfate) | 2mg | 446267024 | HY-15954B | MFCD31382179 | 757.34 | C38H49ClN4O8S
ChemScene | Ethyl 4-oxo-4H-pyran-2-carboxylate | 100mg | 632303729 | CS-0160785 | 1551-45-7 | MFCD17012130 | 168.148 | C8H8O4
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Medchemexpress LLC NBI-31772 | 374620-70-9 | 98.88% | 341.27 | 10 MG
NBI-31772 is a non-selective IGFBP inhibitor with a Ki of 47 nM. It demonstrates neuroprotective effects, reduces infarct volume during cerebral ischemia, and can restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. It is suitable for various research applications.
- Inhibits IGFBP with a Ki of 47 nM
- Demonstrates neuroprotective effects
- Reduces infarct volume during cerebral ischemia
- Restores or enhances proteoglycan synthesis in osteoarticular chondrocytes
- Increases the effect of IGF3 on zebrafish oocyte maturation
- For research use only
eMolecules 2380013-17-0 | Medchem Express | Nampt-IN-5 | 5mg | 572596758 | HY-130606 | 427.508 | C25H25N5O2
Pharmablock | (2R)-2-(methylamino)-3-phenyl-propanoic acid | 25mg | 781214088 | PBA0854 | 56564-52-4 | MFCD00069560 | 179.219 | C10H13NO2
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![eMolecules 274676-47-0 | 7-Methyl-1,2,3,4-tetrahydro-[1,8]naphthyridine | J&W PharmLab LLC | MFCD06739289 | 148.209 | C9H12N2 | 96.000 | Cc1ccc2CCCNc2n1 | 25g | 624168584](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502155749.JPG-250.jpg)
eMolecules 274676-47-0 | 7-Methyl-1,2,3,4-tetrahydro-[1,8]naphthyridine | J&W PharmLab LLC | MFCD06739289 | 148.209 | C9H12N2 | 96.000 | Cc1ccc2CCCNc2n1 | 25g | 624168584
7-Methyl-1,2,3,4-tetrahydro-[1,8]naphthyridine | J&W PharmLab LLC | 274676-47-0 | MFCD06739289 | 148.209 | C9H12N2 | 96.000 | Cc1ccc2CCCNc2n1 | 25g | 624168584
Medchemexpress LLC SR10067 | 1380548-02-6 | 99.2% | 465.58 g·mol⁻1 | C31H31NO3 | 25 MG
SR10067 is a potent, selective, brain-penetrant REV-ERB agonist used as a research tool to study circadian biology, metabolic regulation, and neuropsychiatric disorders. It has reported IC50 values of approximately 160-170 nM and a molecular weight of 465.58 g·mol⁻1.
- Potent, selective REV-ERB agonist with low-nanomolar activity.
- Brain-penetrant small molecule suitable for in vivo studies.
- High chemical purity (≈99.2% by supplier analysis).
- Molecular formula C31H31NO3 and molecular weight 465.58 g·mol⁻1.
- Stable as powder at -20°C for long-term storage.
- Suitable for receptor assays, cell-based studies, and in vivo pharmacology.
eMolecules 1430844-80-6 | Medchem Express | A-1331852 | 5mg | 446270225 | HY-19741 | 658.82 | C38H38N6O3S
Ambeed | Methyl 2-(methylthio)-4-(trifluoromethyl)benzoate | 250mg | 598443895 | A489460 | 192805-69-9 | MFCD14635484 | 250.240 | C10H9F3O2S
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eMolecules 36684-65-8 | 6-Chloro-2,3,4,9-tetrahydro-1h-carbazole | MFCD00541331 | 25g
ChemScene | 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-68-dimethyl-247-trioxo-123478-hexahydropyrido[23-d]pyrimidin-5-yl 4-methylbenzenesulfonate | 100mg | 536836915 | CS-M0423 | 871700-32-2 | MFCD18207186 | 637.420 | C25H21FIN3O6S
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eMolecules 24693-40-1 | 8-Methoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride | J & W PharmLab LLC | MFCD05861545 | 199.680 | C10H14ClNO | 95.000 | Cl.COc1cccc2CCNCc12 | 5g | 289352726
8-Methoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride | J & W PharmLab LLC | 24693-40-1 | MFCD05861545 | 199.680 | C10H14ClNO | 95.000 | Cl.COc1cccc2CCNCc12 | 5g | 289352726
Medchemexpress LLC Norisoboldine | 23599-69-1 | 313.35 | 50 MG
Norisoboldine is an orally active natural aryl hydrocarbon receptor (AhR) agonist. It is a major isoquinoline alkaloid found in Radix Linderae and can be used for the research of rheumatoid arthritis and ulcerative colitis.
- Activates AhR under hypoxic microenvironment.
- Downregulates mRNA expression of miR-31.
- Inhibits glycolysis in hypoxia.
- Promotes Treg differentiation in hypoxia.
- Facilitates disassociation of HSP90/AhR complexes.
- Induces nuclear translocation of AhR.
- Forms AhR/ARNT complexes.
- Reduces severity of joint swelling and erythema in animal models.
- Enhances CYP1A1 expression in colons.
- Suppresses expressions of Glut1 and HK2 in colons.
Medchemexpress LLC 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxy-3-isoquinolinecarboxylic acid | 374620-70-9 | MFCD20274527 | 98.9% | 341.27 g/mol | C17H11NO7 | 5 MG
NBI-31772 (CAS 374620-70-9) is a non-selective inhibitor of insulin-like growth factor binding proteins (IGFBPs), supplied as an analytical standard for research and analytical applications. It is intended for biochemical assays, ligand-binding studies, and analytical method development, and is offered in small milligram package sizes for research use.
- Non-selective IGFBP inhibitor for biochemical assays and binding studies.
- Provided as an analytical standard suitable for method validation and reference.
- Available in small milligram quantities for research-scale experiments.
- Chemical identity and purity supported by certificate of analysis and safety data sheet.
- Soluble in common organic solvents, enabling straightforward assay preparation.
eMolecules 1082658-92-1 | 1,2,3,4-TETRAHYDROISOQUINOLIN-5-AMINE HCL | MFCD08461265 | 1g
Ambeed | 3-Methyl-5-(4455-tetramethyl-132-dioxaborolan-2-yl)benzoic acid | 100mg | 687211899 | A560875 | 1150561-67-3 | MFCD12026101 | 262.110 | C14H19BO4
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eMolecules 372523-75-6 | Medchem Express | TCS-OX2-29 | 5mg | 446255494 | HY-100452 | MFCD26142103 | 397.519 | C23H31N3O3
Ambeed | 6-Chloro-5-methylpyridine-2-carbonitrile | 100mg | 600841941 | A504845 | 875293-89-3 | MFCD18257989 | 152.580 | C7H5ClN2
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eMolecules 53899-17-5 | 8-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE | AstaTech | MFCD07800307 | 163.220 | C10H13NO | 95.000 | COc1cccc2CCCNc12 | 1g | 449746540
8-METHOXY-1,2,3,4-TETRAHYDROQUINOLINE | AstaTech | 53899-17-5 | MFCD07800307 | 163.220 | C10H13NO | 95.000 | COc1cccc2CCCNc12 | 1g | 449746540