Tetrapyrroles and derivatives
Sigma Aldrich Fine Chemicals Biosciences Hemin BioXtra from Porcine5G
REAGENT Hemin BioXtra from Porcine5G
Abcam U-69593, kappa1-opioid receptor agonist, 5MG
MW 356.5 Da, Purity >99%. Potent, selective κ1-opioid receptor agonist (EC50 = 80-109 nM). Active *in vivo*. Antinociceptive.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Necrostatin-1, necroptosis inhibitor, 10MG
MW 259.33 Da, Purity >99%. Potent, specific necroptosis inhibitor (EC₅₀ = 490 nM). Selective allosteric inhibitor of death domain receptor-associated adaptor kinase RIP1 in vitro (EC₅₀ = 182 nM). Caspase independent, programmed necrosis pathway.
The product is subject to the following: Abcam Restricted Use Statement
Strem, An Ascensus Company CAS# 14609-54-2. 1g. meso-Tetra(4-carboxyphenyl)porphine, 98%. MFCD00064860
CAS# 14609-54-2. 1g. meso-Tetra(4-carboxyphenyl)porphine, 98%. MFCD00064860. Molecular Weight: 790.79. Molecular Formula: C48H30N4O8. Color/form: purple pwdr. Strem# 07-1970. http://www.strem.com/catalog/v/07-1970/
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 250mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Cayman Chemical ZInc ProtoporphyrIn-9 10mg
A competitive inhibitor of heme oxygenase that also inhibits soluble guanylyl cyclase and inactivates the NOS isoforms nNOS, iNOS, and eNOS (IC50s = 0.8, 4, and 5 μM, respectively); used to assess iron status and to diagnose iron disorders and has shown therapeutic potential in hyperbilirubinemia
Medchemexpress LLC Hematoporphyrin monomethyl ether | 148471-91-4 | MFCD32215011 | 95.0% | 1225.43 | C70H80N8O12 | 5 MG
Hematoporphyrin monomethyl ether is a porphyrin-based photosensitizer used in photodynamic therapy and related biochemical research. It is supplied as a purple to purplish-red solid with high purity and characterized solubility in DMSO; handle and store protected from light.
- Solid, purple to purplish red appearance
- Purity approximately 95.0%
- Soluble in DMSO (≈62.5 mg/mL); in vivo formulations documented
- Storage: solid at 4°C; solutions at -80°C (6 months) or -20°C (1 month); protect from light
- Used as a photosensitizer for photodynamic therapy research and tissue visualization
Medchemexpress LLC Protoporphyrin IX | 553-12-8 | 96.1% | 562.66 g/mol | C34H34N4O4 | 10 MG
Protoporphyrin IX analytical standard for research and analytical applications, commonly used in studies of heme biosynthesis, photodynamic and sonodynamic agents, and fluorescence-based assays. Supplied as a small laboratory pack suitable for analytical testing.
- Analytical standard with reported purity of 96.09%.
- Molecular weight 562.66 g/mol and formula C34H34N4O4.
- Provided in a 10 mg laboratory pack for assay and method validation.
- Suitable for photodynamic and sonodynamic research and fluorescence assays.
- Certificate of analysis and safety datasheet available for quality and handling information.
Enzo Life Sciences Zinc(II) Protoporphyrin IX (25mg). CAS: 15442-64-5
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter. Purity: ≥95% (TLC). Solubility: Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures. Long Term Storage: -20°C.
Medchemexpress LLC Phthalocyanine | 574-93-6 | 98.0% | 500MG
Phthalocyanine | 574-93-6 | 98.0% | 500MG
Selleck Chemical LLC Methylcobalamin S4994-25mg
Methylcobalamin (Mecobalamin Vancomin Methycobal Cobametin) is one active form of vitamin B12 which can directly participate in homocysteine metabolism It is used to treat some nutritional diseases and other diseases in clinic such as Alzheimer s disease and rheumatoid arthritis