Tetrapyrroles and derivatives
Abcam AMD3100 octahydrochloride, C x CR4 antagonist, 5MG
MW 794.5 Da, Purity >99%. Plerixafor (hydrochloride) is a macrocyclic compound that acts as an irreversible antagonist against the binding of CXCR4 with its ligand, SDF-1 (CXCL12). It suppresses infection by HIV with an IC₅₀ value of 1-10 ng/ml with selectivity toward CXCR4-tropic virus. Plerixafor mobilizes hematopoietic stem and progenitor cells for transplant better than G-CSF alone. It also increases T-cell trafficking in the blood and spleen as well as the central nervous system. Plerixafor regulates the growth of primary and metastic breast cancer cells and inhibits dissemination of ovarian carcinoma cells.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Chlorin e6(Synonyms: Ce6, Chlorophyllin e6, Chlorophyll derivative e6, Chlorin-e6, Chlorin e-6), 50mg, CAS: 19660-77-6.
Chlorin e6 (Ce6 CAS 19660-77-6) is a second-generation photosensitizer utilized in photodynamic therapy (PDT) research with demonstrated anticancer activity when activated by laser irradiation Upon irradiation Ce6 generates reactive oxygen species mediating cytotoxic effects and cellular apoptosis In mouse models intravenous administration of Ce6 (2 5 10 mg/kg) combined with irradiation (50 200 J/cm ) resulted in complete elimination of implanted fibrosarcomas In clinical trials for bronchogenic superficial squamous cell carcinoma Ce6-based PDT (40 mg/m 100 J/cm ) produced complete response rates up to 82 9% underscoring its utility for cancer therapy studies
Cayman Chemical Mn III ProtoporphyrIn IX Chl
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Cayman Chemical Mn III ProtoporphyrIn IX Chl
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Sigma Aldrich Fine Chemicals Biosciences 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine Dye content 95 % | 51094-17-8 | MFCD00191501 | 1G
5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine Dye content 95 % | Mol Wt: 678.73 | 51094-17-8 | MFCD00191501 | 1G
Abcam Monosodium urate, Pro-inflammatory agent, 2MG
MW 190.09 Da. NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Sigma Aldrich Fine Chemicals Biosciences 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine Dye content 95 % | 51094-17-8 | MFCD00191501 | 250MG
5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine Dye content 95 % | Mol Wt: 678.73 | 51094-17-8 | MFCD00191501 | 250MG
STEMCELL Technologies Methylcobalamin, Size: 100 mg
Methylcobalamin is a vitamin B12 analog and a coenzyme involved in homocysteine metabolism (Okada et al.). Methylcobalamin elevates the activities of ERK1/2 and AKT and improves nerve regeneration in rats (Okada et al.). This small molecule has therapeutic potential for treating nervous disorders (Okada et al.).DIFFERENTIATION· Promotes Schwann cell differentiation in vitro (Nishimoto et al.).DISEASE MODELING· Promotes neuronal survival in rats (Okada et al.).
Frontier Specialty Chemicals 250MG MESO-TETRA(P-HYDROXYPHEN
This item has a minimum qty of 3 per supplier requirements.
meso-Tetra(p-hydroxyphenyl)porphine; CAS: 51094-17-8; 250mg
Frontier Specialty Chemicals 5G MESO-TETRA(4-PYRIDYL)PORPHI
meso-Tetra(4-pyridyl)porphine; CAS: 16834-13-2; 5g
Enzo Life Sciences Protoporphyrin IX (free acid) (300mg). CAS: 553-12-8
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
Enzo Life Sciences Zinc(II) Protoporphyrin IX (100mg). CAS: 15442-64-5
Potent and selective inhibitor of heme oxygenase (Ki=3nM), the enzyme that generates carbon monoxide (CO). Inhibits soluble guanylyl cyclase. Produces a time- and concentration-dependent inactivation of all three isoforms of nitric oxide synthase (IC50=0.8µM, 4.0µM, and 5.0µM for nNOS (NOS I), iNOS (NOS II) and eNOS (NOS III), respectively). Does not cross the blood-brain barrier. An useful tool to elucidate the role of CO in signal transduction and as a neurotransmitter. Purity: ≥95% (TLC). Appearance: Dark solid. Solubility: Soluble in pyridine, dimethyl formamide or DMSO. Colloidal in aqueous base; slightly soluble in aqueous base/organic solvent mixtures. Long Term Storage: -20°C.
eMolecules 3-Hydroxy-4-methyl-2(3H)-thiazolethione | 49762-08-5 | MFCD00077793 | 5g
Combi-Blocks, Inc. | 3-Hydroxy-4-methyl-2(3H)-thiazolethione | 5g | 603151825 | QA-9143 | 95.000 | 49762-08-5 | MFCD00077793 | 147.210 | C4H5NOS2
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![Chemscene ChemScene | 3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide | 5G | CS-0106913 | 0.98 | 50978-45-5| MFCD23380208 | 211.2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/CS-0106913.JPG-250.jpg)
Chemscene ChemScene | 3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide | 5G | CS-0106913 | 0.98 | 50978-45-5| MFCD23380208 | 211.2
ChemScene | 3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide | 5G | CS-0106913 | 0.98 | 50978-45-5| MFCD23380208 | 211.2