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MW 211.15 Da, Purity >99%. Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo. Soluble in 1 ml water to give specified mM/ml concentration. Find out more. .
MW 252.27 g/mol, Purity >99%. High affinity α4β2 nAChR selective agonist (Ki = 26 nM). Selective for CNS nAChR over muscle, ganglionic or enteric ACh receptors (EC₅₀ = 732 nM in rat thalamic synaptosomes).
MW 252.27 g/mol, Purity >99%. High affinity α4β2 nAChR selective agonist (Ki = 26 nM). Selective for CNS nAChR over muscle, ganglionic or enteric ACh receptors (EC₅₀ = 732 nM in rat thalamic synaptosomes).
MW 360.4 Da, Purity >99%. Potent, reversible activator of AMP-activated protein kinase (AMPK) (EC₅₀ = 0.8 μM). Directly activates native rat AMPK by mimicking the effects of AMP - it activates AMPK both allosterically and by inhibiting dephosphorylation of AMPK. Shown to inhibit Na+-K+-ATPase at higher concentrations (IC₅₀ = 57 μM) . Inhibits differentiation of adipocytes.
MW 360.4 Da, Purity >99%. Potent, reversible activator of AMP-activated protein kinase (AMPK) (EC₅₀ = 0.8 μM). Directly activates native rat AMPK by mimicking the effects of AMP - it activates AMPK both allosterically and by inhibiting dephosphorylation of AMPK. Shown to inhibit Na+-K+-ATPase at higher concentrations (IC₅₀ = 57 μM) . Inhibits differentiation of adipocytes.