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Fluorescein-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs (Proteolysis Targeting Chimeras) consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins. This product is intended for research use only.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Intended for research use only
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Fluorescein-PEG3-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, one for an E3 ubiquitin ligase and the other for the target protein, facilitating the selective degradation of target proteins via the intracellular ubiquitin-proteasome system.
PEG-based PROTAC linker
Utilized in the synthesis of PROTACs
Facilitates selective degradation of target proteins
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Fluorescein-PEG3-amine is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These compounds employ the intracellular ubiquitin-proteasome system for selective degradation of target proteins. The PROTACs achieve this by connecting two different ligands via a linker, with one ligand binding to an E3 ubiquitin ligase and the other to the target protein.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Fluorescein-PEG3-amine is a PEG-based PROTAC linker comprising a fluorescein fluorophore connected through a three-unit polyethylene glycol spacer to a terminal primary amine. It is supplied as a solid for research use and is intended for conjugation reactions in chemical biology and PROTAC synthesis; follow frozen storage recommendations for long-term stability.