Thiolactams
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Cayman Chemical 2-ThIouracIl 250g
An antithyroid agent and a melanoma seeker; reduces sodium iodide-induced increases in thyroid weight in a mouse model of goiter at 2.5 mg/animal per day; preferentially accumulates into tumor cell melanin in a mouse model of melanoma; inhibits nNOS (Ki = 20 µM)
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Medchemexpress LLC 4-Thiouridine | 13957-31-8 | 99.98% | 260.27 | 25 MG
4-Thiouridine is a ribonucleoside analog, widely used in RNA analysis and (m)RNA labeling. It inhibits rRNA synthesis and causes a nucleolar stress response.
- Functions as a ribonucleoside analog.
- Utilized for RNA analysis and (m)RNA labeling.
- Labels and purifies nascent rRNA at concentrations of 0-10 μM without significantly affecting rRNA synthesis.
- Strongly inhibits the production and processing of rRNA at concentrations of ≥50 μM.
- Targets nucleoside antimetabolite/analog.
- Acts on the cell cycle/DNA damage pathway.