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2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-Thiouracil (CAS 141-90-2) is a sulfur-containing derivative of uracil that functions as an inhibitor of thyroid hormone synthesis It exerts its antihyperthyroid effects by interfering with the enzymatic iodination of tyrosine residues within thyroglobulin thereby suppressing the production of triiodothyronine (T3) and thyroxine (T4) Due to its capacity to modulate thyroid function 2-Thiouracil is utilized in biomedical research to study thyroid hormone regulation and associated disorders as well as to model hypothyroid states in experimental settings
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
4-Thiouridine (CAS 13957-31-8) is a thiol-substituted ribonucleoside analog commonly utilized in RNA research for photoactivatable labeling and RNA cross-linking experiments Structurally 4-thiouridine differs from natural uridine solely by the substitution of a sulfur atom at the 4-position of the nucleotide base Due to this close structural similarity it integrates into RNA sequences with minimal disruption preserving typical base-pairing properties and RNA functionality Upon UV irradiation the incorporated thiol group induces covalent short-range RNA RNA cross-links facilitating detailed analysis of RNA interactions turnover rates and dynamics within cellular contexts
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
4-Thiouridine (CAS 13957-31-8) is a thiol-substituted ribonucleoside analog commonly utilized in RNA research for photoactivatable labeling and RNA cross-linking experiments Structurally 4-thiouridine differs from natural uridine solely by the substitution of a sulfur atom at the 4-position of the nucleotide base Due to this close structural similarity it integrates into RNA sequences with minimal disruption preserving typical base-pairing properties and RNA functionality Upon UV irradiation the incorporated thiol group induces covalent short-range RNA RNA cross-links facilitating detailed analysis of RNA interactions turnover rates and dynamics within cellular contexts
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-Thiouridine is a thiolated uridine nucleoside used in biochemical and nucleic acid research. The compound contains a sulfur substituent at the 2-position of the nucleobase and is provided as a high-purity solid or as pre-formulated DMSO solutions for assay-ready use.
High purity suitable for research use.
Molecular weight 260.27 g/mol; formula C9H12N2O5S.
Available in solid quantities from 50 mg up to 50 g.
Offered as 10 mM DMSO solutions for convenience.
Commonly used in RNA modification studies and enzymology.
Supplied with a certificate of analysis documenting batch purity.
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