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Filtered Search Results
eMolecules 6164-79-0 | methyl pyrazine-2-carboxylate | Pharmablock | MFCD00014611 | 138.126 | C6H6N2O2 | 97.000 | COC(=O)c1cnccn1 | 5g | 596114927
methyl pyrazine-2-carboxylate | Pharmablock | 6164-79-0 | MFCD00014611 | 138.126 | C6H6N2O2 | 97.000 | COC(=O)c1cnccn1 | 5g | 596114927
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eMolecules 1013-23-6 | Dibenzo[b,d]thiophene 5-oxide | ChemScene | MFCD00046902 | 200.260 | C12H8OS | 96.000 | O=s1c2ccccc2c2ccccc12 | 25g | 711937355
Dibenzo[b,d]thiophene 5-oxide | ChemScene | 1013-23-6 | MFCD00046902 | 200.260 | C12H8OS | 96.000 | O=s1c2ccccc2c2ccccc12 | 25g | 711937355
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Medchemexpress LLC Bisantrene dihydrochloride | 71439-68-4 | 98.9% | 471.39 g/mol | C22H24Cl2N8 | 5 MG
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Bisantrene dihydrochloride is an anthracycline-class antitumor compound used in preclinical research. It intercalates into DNA, inhibits eukaryotic type II topoisomerases, and has demonstrated cytotoxic activity across multiple experimental tumor models. The material is provided as a solid for laboratory use with manufacturer storage and solubility guidance for solution preparations.
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eMolecules 1224844-66-9 | 2-Aminobenzo[d]oxazol-5-ylboronic acid pinacol ester | Combi-Blocks, Inc. | MFCD13182075 | 260.100 | C13H17BN2O3 | 98.000 | CC1(C)OB(OC1(C)C)c1ccc2oc(N)nc2c1 | 10g | 882681049
2-Aminobenzo[d]oxazol-5-ylboronic acid pinacol ester | Combi-Blocks, Inc. | 1224844-66-9 | MFCD13182075 | 260.100 | C13H17BN2O3 | 98.000 | CC1(C)OB(OC1(C)C)c1ccc2oc(N)nc2c1 | 10g | 882681049
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Medchemexpress LLC Bisantrene dihydrochloride | 71439-68-4 | 98.9% | 471.39 g/mol | C22H24Cl2N8 | 25 MG
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Bisantrene dihydrochloride is a research-grade antitumor compound that intercalates DNA and inhibits eukaryotic type II topoisomerases. Supplied as a solid for in vitro and preclinical research, it is used in cancer biology and pharmacology studies for mechanistic and efficacy assays.
- High purity (98.85%) suitable for research use.
- Confirmed molecular weight 471.39 g/mol and formula C22H24Cl2N8.
- Available in multiple pack sizes, including 25 MG quantities.
- Soluble in DMSO and water with recommended preparation procedures.
- Store sealed and protect from moisture; observe solvent storage temperature guidelines.
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Apexbio Technology LLC GSK-LSD1 2HCl 2102933-95-7 10mM (in 1mL DMSO)
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GSK-LSD1 2HCl (CAS 2102933-95-7) is a selective irreversible inhibitor of lysine-specific demethylase 1A (LSD1) a flavin-dependent histone demethylase that modulates mono- and dimethylated lysine residues and is implicated in processes such as oocyte growth and tissue-specific differentiation GSK-LSD1 2HCl inhibits LSD1 with an IC50 of 16 nM and exhibits over 1000-fold selectivity against related FAD-utilizing enzymes including LSD2 MAO-A and MAO-B In cancer cell lines it demonstrates EC50 values below 5 nM for both gene expression modulation and growth inhibition GSK-LSD1 2HCl serves as a valuable chemical probe in epigenetics and cancer research
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eMolecules 16694-17-0 | 4-Bromo-thiophene-3-carboxylic acid | J & W PharmLab, LLC | MFCD01233020 | 207.040 | C5H3BrO2S | 96.000 | OC(=O)c1cscc1Br | 5g | 250022075
4-Bromo-thiophene-3-carboxylic acid | J & W PharmLab, LLC | 16694-17-0 | MFCD01233020 | 207.040 | C5H3BrO2S | 96.000 | OC(=O)c1cscc1Br | 5g | 250022075
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eMolecules 16694-17-0 | 4-Bromo-thiophene-3-carboxylic acid | Chem-Impex | MFCD01233020 | 207.040 | C5H3BrO2S | 95.000 | OC(=O)c1cscc1Br | 1g | 112751312
4-Bromo-thiophene-3-carboxylic acid | Chem-Impex | 16694-17-0 | MFCD01233020 | 207.040 | C5H3BrO2S | 95.000 | OC(=O)c1cscc1Br | 1g | 112751312
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Medchemexpress LLC Ym-244769 dihydrochloride | 1780390-65-9 | 516.39 | 25 MG
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Ym-244769 dihydrochloride is a potent, selective, and orally active Na+/Ca2+ exchanger (NCX) inhibitor. It preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode), with IC50 values of 18 nM and 50 nM, respectively. This compound efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage. It can also increase urine volume and urinary excretion of electrolytes in mice.
- Potent and selective Na+/Ca2+ exchanger (NCX) inhibitor.
- Preferentially inhibits NCX3.
- Suppresses unidirectional outward NCX current (Ca2+ entry mode).
- Protects against hypoxia/reoxygenation-induced neuronal cell damage.
- Increases urine volume and urinary excretion of electrolytes.
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Apexbio Technology LLC GSK-LSD1 2HCl 2102933-95-7 100mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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GSK-LSD1 2HCl (CAS 2102933-95-7) is a selective irreversible inhibitor of lysine-specific demethylase 1A (LSD1) a flavin-dependent histone demethylase that modulates mono- and dimethylated lysine residues and is implicated in processes such as oocyte growth and tissue-specific differentiation GSK-LSD1 2HCl inhibits LSD1 with an IC50 of 16 nM and exhibits over 1000-fold selectivity against related FAD-utilizing enzymes including LSD2 MAO-A and MAO-B In cancer cell lines it demonstrates EC50 values below 5 nM for both gene expression modulation and growth inhibition GSK-LSD1 2HCl serves as a valuable chemical probe in epigenetics and cancer research
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Cayman Chemical 3 Arachidonic Acidmethyl es
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A rare polyunsaturated fatty acid; a neutral, lipid-soluble form of the rare fatty acid ω-3 arachidonic acid
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Medchemexpress LLC Dicarbine dihydrochloride | 33162-17-3 | 98.9% | 1 MG
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Dicarbine dihydrochloride is a dopamine receptor blocker that blocks dopamine receptors in various brain parts. It prevents the depression of conditioned defense reflexes caused by stimulation of the mesencephalic portion of the reticular formation. This product could be used in schizophrenia and alcoholic psychosis studies.
- Blocks dopamine receptors in various brain parts.
- Prevents depression of conditioned defense reflexes.
- Suitable for schizophrenia and alcoholic psychosis studies.
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Medchemexpress LLC Nolatrexed dihydrochloride | 152946-68-4 | 98.5% | 357.26 | 50 MG
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Nolatrexed dihydrochloride (AG 337) is an orally active and non-competitive lipophilic inhibitor of thymidylate synthase with a Ki of 11 nM for human thymidylate synthase. It interacts at the folate cofactor binding site of the enzyme. Nolatrexed dihydrochloride increases sulfotransferases and induces cell cycle arrest in the S phase of cancer cells. It also exhibits anticancer activity against cervical cancer.
- Orally active and non-competitive lipophilic inhibitor of thymidylate synthase.
- Interacts at the folate cofactor binding site of the enzyme.
- Increases sulfotransferases.
- Induces cell cycle arrest in the S phase of cancer cells.
- Exhibits anticancer activity against cervical cancer.
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Apexbio Technology LLC Ranolazine 2HCl 95635-56-6 100mg
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Ranolazine 2HCl (CAS 95635-56-6) is a small molecule frequently utilized in cardiovascular research for its antianginal and antiarrhythmic activities It modulates cardiac metabolism by partially inhibiting fatty acid -oxidation thereby increasing reliance on glucose oxidation This metabolic shift is mediated through activation of pyruvate dehydrogenase in ischemic myocytes enhancing glucose utilization during myocardial ischemia Ranolazine 2HCl s ability to alter substrate preference and improve cellular energetics under hypoxic conditions supports its application in studies of cardiac ischemia arrhythmias and myocardial metabolism
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Apexbio Technology LLC H 89 2HCl 130964-39-5 10mM (in 1mL DMSO)
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H 89 2HCl (CAS 130964-39-5) is a small-molecule inhibitor targeting cyclic AMP-dependent protein kinase (PKA) It exhibits a Ki of approximately 48 nM toward PKA and demonstrates substantial selectivity compared to related kinases such as PKG (about 10-fold) PKC MLCK calmodulin kinase II and casein kinases (approximately 500-fold) In PC12D cells H 89 at micromolar concentrations suppresses forskolin-induced phosphorylation events and neurite outgrowth without altering intracellular cAMP levels Due to its selective inhibitory profile H 89 is widely utilized in cell signaling studies examining cAMP-dependent pathways
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