Thiopyrans
Medchemexpress LLC 11-Dodecyn-1-ol | 18202-10-3 | 182.30 | 5 G
11-Dodecyn-1-ol is a synthetic intermediate used for the creation of the sex pheromone (Z,E)-11,13,15-Hexadecatrienyl acetate, which is associated with *Thaumetopoea processionea*.
- Intermediate for sex pheromone synthesis.
- For research use only.
Medchemexpress LLC Tazarotene (AGN 190168) | 118292-40-3 | C21H21NO2S | 5 MG
Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist used for treating plaque psoriasis and acne vulgaris. It is also a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Used for monotherapy or adjuvant therapy for psoriasis and acne
- Upregulates tumor suppressor tazarotene induced gene 3
- Suppresses gene expression of MRP-8 and SKALP in human epidermal cell cultures
- Delivered into the skin via topical gel application
- Metabolized to active tazarotenic acid with short systemic residence time
- Blocks induction of ornithine decarboxylase activity
Medchemexpress LLC Tazarotene | 118292-40-3 | MFCD00867628 | C21H21NO2S | 1 ML
Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist used for treating plaque psoriasis and acne vulgaris. It is also a click chemistry reagent containing an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Selective retinoic acid receptor (RAR) agonist
- Used for treating plaque psoriasis
- Used for treating acne vulgaris
- Functions as a click chemistry reagent
- Contains an alkyne group for CuAAc reactions
Medchemexpress LLC 3-Bromopropan-1-ol-d6 | 284474-43-7 | 145.03 | 25 MG
3-Bromopropan-1-ol-d6 is a deuterium-labeled variant of 3-Bromopropan-1-ol, which is an endogenous metabolite. It is notably upregulated in buffaloes during the estrus period and is applicable in buffalo estrus research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 3-Bromopropan-1-ol-d6 | 284474-43-7 | MFCD01075414 | 145.03 | 100 MG
3-Bromopropan-1-ol-d6 is the deuterium labeled form of 3-Bromopropan-1-ol, an endogenous metabolite significantly upregulated during the estrus period in buffaloes. This compound can be utilized in buffalo estrus research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Apexbio Technology LLC Tazarotene 118292-40-3 10mM (in 1mL DMSO)
Tazarotene (118292-40-3) is a small-molecule agonist targeting retinoic acid receptors (RARs) primarily the RAR- and RAR- subtypes It is designed to modulate gene transcription via selective activation of RARs thereby regulating cellular processes such as proliferation differentiation and apoptosis Tazarotene exerts its biological activity through rapid hydrolysis to its active metabolite tazarotenic acid which binds to RARs and induces expression of genes including the tumor suppressor TIG3 Based on these pharmacological properties Tazarotene holds research potential in the topical treatment of dermatological conditions such as psoriasis acne vulgaris and hyperproliferative skin disorders as well as in mechanistic studies of retinoid-responsive signaling pathways