6-(Dimethylamino)purine is a serine threonine protein kinase inhibitor. It can inhibit prolactin-induced expression of lactoprotein genes in rabbit mammary gland cells and affect the maturation of mammalian oocytes. It leads to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induces apoptosis in lymphoma cells.
- Inhibits protein kinases
- Blocks DNA synthesis in activated mammalian oocytes
- Affects sperm motility and vitality
- Induces apoptosis in lymphoma cells
- Accelerates transition to interphase in activated mouse oocytes