Amidines
Medchemexpress LLC PTC-209 hydrobromide | 1217022-63-3 | 99.0% | 576.10 | C17H14Br3N5OS | 10 MG
PTC-209 hydrobromide is a small-molecule inhibitor of BMI-1 intended for research use. It has been reported to inhibit BMI-1 activity (IC50 ~0.5 μM in HEK293T cells) and has been used in preclinical studies to impair tumor-initiating cells and affect the tumor microenvironment.
- Specific BMI-1 inhibitor with reported IC50 ~0.5 μM in HEK293T cells.
- High purity (99.0%).
- Solid, light yellow to yellow appearance.
- Available in small quantities, including a 10 mg vial.
- Recommended storage: 4°C; in solvent: -80°C (6 months) or -20°C (1 month).
Apexbio Technology LLC Teneligliptin hydrobromide 906093-29-6 50mg
Teneligliptin hydrobromide (CAS 906093-29-6) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor exhibiting competitive inhibition of human and rat plasma DPP-4 with an IC50 of approximately 1 nM DPP-4 also known as CD26 is a cell surface protease involved in immunoregulation signal transduction and apoptosis In vitro Teneligliptin hydrobromide reduces reactive oxygen species and modulates cell cycle and apoptotic gene expression in human endothelial cells exposed to high glucose In vivo it ameliorates hepatic steatosis and metabolic disturbances in murine models partly through activation of hepatic AMPK This compound supports studies of metabolic oxidative and inflammatory pathways
Apexbio Technology LLC Teneligliptin hydrobromide 906093-29-6 10mg
Teneligliptin hydrobromide (CAS 906093-29-6) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor exhibiting competitive inhibition of human and rat plasma DPP-4 with an IC50 of approximately 1 nM DPP-4 also known as CD26 is a cell surface protease involved in immunoregulation signal transduction and apoptosis In vitro Teneligliptin hydrobromide reduces reactive oxygen species and modulates cell cycle and apoptotic gene expression in human endothelial cells exposed to high glucose In vivo it ameliorates hepatic steatosis and metabolic disturbances in murine models partly through activation of hepatic AMPK This compound supports studies of metabolic oxidative and inflammatory pathways