Aralkylamines
eMolecules 2096331-52-9 | 3-Bromo-5-(1-t-BOC-piperidin-4-yl)methoxyphenylboronic acid | Combi-Blocks | MFCD18087693 | 414.100 | C17H25BBrNO5 | 98.000 | CC(C)(C)OC(=O)N1CCC(COc2cc(Br)cc(c2)B(O)O)CC1 | 1g | 117524885
3-Bromo-5-(1-t-BOC-piperidin-4-yl)methoxyphenylboronic acid | Combi-Blocks | 2096331-52-9 | MFCD18087693 | 414.100 | C17H25BBrNO5 | 98.000 | CC(C)(C)OC(=O)N1CCC(COc2cc(Br)cc(c2)B(O)O)CC1 | 1g | 117524885
Medchemexpress LLC Apraclonidine hydrochloride | 73218-79-8 | 99.0% | 1 ML
Apraclonidine hydrochloride is a selective α2 and weak α1 receptor agonist that effectively lowers intraocular pressure in human eyes. It is a topical ophthalmic solution with the ability to elevate the eyelid. Its ocular hypotensive effects are primarily attributed to reduced aqueous humor synthesis and vasoconstrictor actions at the anterior segment branches of the ophthalmic artery.
- Used topically for glaucoma.
- Penetrates the cornea and blood-brain barrier to a lesser extent, resulting in fewer adverse systemic effects.
Medchemexpress LLC Amitriptyline hydrochloride | 549-18-8 | MFCD00012537 | 99.9% | 1 ML
Amitriptyline hydrochloride is an orally active tricyclic antidepressant primarily blocking SERT and NET, which elevates 5-hydroxytryptamine and norepinephrine in the synaptic cleft. It also functions as an α2A and TrkA/TrkB receptor agonist, providing analgesic and neurotrophic benefits by inhibiting cell apoptosis. This compound can reduce inflammation, angiogenesis, and fibrosis. It binds to DAT and various other receptors, while also capable of blocking sodium and hERG potassium channels.
- Primarily blocks SERT and NET
- Increases 5-hydroxytryptamine and norepinephrine in synaptic cleft
- Acts as α2A and TrkA/TrkB receptor agonist
- Provides analgesic and neurotrophic activities
- Inhibits cell apoptosis
- Reduces inflammation, angiogenesis, and fibrosis
- Binds to DAT and multiple cholinergic, H1, and adrenergic receptors
- Can block sodium and hERG potassium channels
- For research use only
Medchemexpress LLC Protriptyline hydrochloride | 1225-55-4 | 1 ML
Protriptyline hydrochloride is a potent tricyclic antidepressant (TCA) that inhibits Acetylcholinesterase (AChE) activity and Aβ self-assembly. It is used in the study of depression and Alzheimer's disease. In vitro, it causes cytotoxicity in PC3 cells. In vivo, it has been shown to improve spatial learning and retention memory in rat models of Alzheimer's disease.
- Inhibits AChE activity with an IC50 value of 0.06 mM.
- Inhibits Aβ self-assembly.
- Causes cytotoxicity in PC3 cells.
- Improves spatial learning and retention memory in rat models of Alzheimer's disease.
Medchemexpress LLC Pivmecillinam hydrochloride (Standard) | 32887-03-9 | 99.90% | 50 MG
Pivmecillinam hydrochloride (Standard) is an analytical standard of Pivmecillinam (hydrochloride). This orally active proagent of mecillinam is an extended-spectrum penicillin antibiotic intended for research and analytical applications.
- Used as a reference standard for assays
- Suitable for qualitative, quantitative, and methodological research experiments
- Applicable in HPLC, GC, and MS
Medchemexpress LLC Norfluoxetine hydrochloride | 57226-68-3 | 99.6% | 331.76 | 1 ML
Norfluoxetine hydrochloride is an active N-demethylated metabolite of Fluoxetine, a selective serotonin (5-HT) reuptake inhibitor. It is formed by the metabolism of Fluoxetine via cytochrome P450 enzymes. This compound inhibits 5-HT uptake and exhibits anticonvulsant activity, also inhibiting CaV3.3 T current with an IC50 of 5 μM.
- Active N-demethylated metabolite
- Inhibits 5-HT uptake
- Inhibits CaV3.3 T current
- Possesses anticonvulsant activity
- Targets 5-HT receptor
- Targets CaV3.3 with an IC50 of 5 μM
Chemscene ChemScene | (2-Bromopyridin-3-yl)methanamine | 250MG | CS-0147258 | 0.97 | 205744-15-6| MFCD07375377 | 187.04
ChemScene | (2-Bromopyridin-3-yl)methanamine | 250MG | CS-0147258 | 0.97 | 205744-15-6| MFCD07375377 | 187.04
Chemscene ChemScene | Naphthalen-1-ylmethanamine hydrochloride | 25G | CS-0139353 | 0.97 | 39110-74-2| MFCD15147375 | 193.68
ChemScene | Naphthalen-1-ylmethanamine hydrochloride | 25G | CS-0139353 | 0.97 | 39110-74-2| MFCD15147375 | 193.68
eMolecules 2375272-95-8 | pyridazin-3-ylmethanamine;dihydrochloride | 1g
Ambeed | 2-Amino-6-methylbenzonitrile | 250mg | 552721079 | A381794 | 56043-01-7 | MFCD00058686 | 132.166 | C8H8N2
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Medchemexpress LLC Chloropyramine hydrochloride | 6170-42-9 | 99.6% | 1 ML
Chloropyramine hydrochloride is a histamine receptor H1 antagonist that also inhibits the biochemical function of VEGFR-3 and FAK. It is intended for research use only and not for patient use. In vitro studies have shown that it causes a significant reduction in the viability of various human cancer cell lines and induces apoptosis in breast cancer cells overexpressing VEGFR-3. In vivo, it has been observed to dramatically reduce tumor growth in model systems, with a low-dose combination with doxorubicin showing a prolonged anti-tumor effect.
- Histamine receptor H1 antagonist
- Inhibits biochemical function of VEGFR-3 and FAK
- Demonstrates cytotoxicity against various human cancer cell lines in vitro
- Induces apoptosis in VEGFR-3 overexpressing breast cancer cells
- Reduces tumor growth in vivo
- Enhanced anti-tumor effect when combined with doxorubicin
Medchemexpress LLC Amitriptyline hydrochloride | 549-18-8 | 99.0% | 50 MG
Amitriptyline hydrochloride | 549-18-8 | 99.0% | 50 MG
Medchemexpress LLC Phenylephrone hydrochloride | 94240-17-2 | MFCD01727458 | 25mg
Phenylephrone Hydrochloride is a Phenylephrine (HY-B0769) impurity
Medchemexpress LLC Navlimetostat hydrochloride | 99.6% | 501.34 | 25 MG
Navlimetostat hydrochloride is a potent, orally active, and selective PRMT5-MTA complex inhibitor. It exhibits antineoplastic activity both in vitro and in vivo, making it a valuable compound for cancer studies.
- Potent, orally active, selective inhibitor of the PRMT5-MTA complex
- IC50s are 3.6 nM for PRMT5-MTA and 20.5 nM for PRMT5
- Binds to the PRMT5-MTA complex with a KD value of 0.14 pM
- Demonstrates antineoplastic activity in both in vitro and in vivo models
- Used in research for cancer studies
- Inhibits PRMT5 activity in MTAP-deleted HCT116 cells
- Inhibits cell viability in MTAP del HCT116 cells
![eMolecules 952958-78-0 | 4-(2-Aminoethyl)-5-(2-furyl)isoxazol-3(2h)-one | Combi-Blocks | MFCD09832473 | 194.190 | C9H10N2O3 | 95.000 | NCCc1c(o[nH]c1=O)-c1ccco1 | 1g | 205397142](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502188340.JPG-250.jpg)
eMolecules 952958-78-0 | 4-(2-Aminoethyl)-5-(2-furyl)isoxazol-3(2h)-one | Combi-Blocks | MFCD09832473 | 194.190 | C9H10N2O3 | 95.000 | NCCc1c(o[nH]c1=O)-c1ccco1 | 1g | 205397142
4-(2-Aminoethyl)-5-(2-furyl)isoxazol-3(2h)-one | Combi-Blocks | 952958-78-0 | MFCD09832473 | 194.190 | C9H10N2O3 | 95.000 | NCCc1c(o[nH]c1=O)-c1ccco1 | 1g | 205397142
Medchemexpress LLC 4-(aminomethyl)-2-methoxyphenol; hydrochloride | 7149-10-2 | MFCD00012864 | 99.8% | 189.64 g/mol | C8H12ClNO2 | 50 G
Vanillylamine hydrochloride is the hydrochloride salt of vanillylamine, supplied as a high-purity biochemical reagent for life-science research. It serves as a synthetic building block and intermediate for studies of capsaicinoid pathways and is suitable for analytical and preparative applications requiring a stable amine reagent.
- High purity (≈99.8%) suitable for research applications.
- White to off-white solid with consistent lot quality.
- Molecular formula C8H12ClNO2 and molecular weight 189.64 g/mol.
- Stable under recommended storage conditions for extended shelf life.
- Available in multiple package sizes for bench-scale synthesis and supply.