Aralkylamines
Medchemexpress LLC Protriptyline hydrochloride | 1225-55-4 | 299.84 | 50 MG
Protriptyline hydrochloride is a potent tricyclic antidepressant (TCA). It inhibits AChE activity with an IC50 value of 0.06 mM and inhibits Aβ self-assembly. It can be used for the study of depression and Alzheimer's disease.
- Potent tricyclic antidepressant (TCA)
- Inhibits AChE activity with an IC50 value of 0.06 mM
- Inhibits Aβ self-assembly
- Suitable for studies on depression and Alzheimer's disease
- Demonstrates cytotoxicity in PC3 cells (in vitro)
- Improves spatial learning and retention memory in STZ treated rats (in vivo)
Chem-Impex International, Inc. (S)-(-)-alpha-Methylbenzylamine | MFCD00064406 | 100G
(S)-(-)-alpha-Methylbenzylamine, MFCD00064406, 100G
Medchemexpress LLC Teneligliptin hydrobromide hydrate | 1572583-29-9 | 99.97% | 426.58 | 25 MG
Teneligliptin hydrobromide hydrate is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor with IC50s of 0.37 and 0.29 nM for human and rat DPP-4, respectively. It improves blood glucose levels and is utilized in research related to type 2 diabetes mellitus.
- Prevents activation of NLRP3 inflammasome and injury in primary mouse cardiomyocytes
- Protects against hypoxia/reoxygenation-induced endothelial cell injury
- Inhibits inflammation and apoptosis in H9c2 cells
- Attenuates myocardial hypertrophy and injury in diabetic cardiomyopathy mice
- Prevents obesity and related manifestations in high-fat diet-induced obesity models
Medchemexpress LLC Teneligliptin hydrobromide | 906093-29-6 | 99.8% | 628.86 | 1 ML
Teneligliptin hydrobromide is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor, demonstrating IC50s of 0.37 nM for human DPP-4 and 0.29 nM for rat DPP-4. This compound improves blood glucose levels and is utilized in research pertaining to type 2 diabetes mellitus.
- Prevents activation of the NLRP3 inflammasome and associated injury.
- Protects against hypoxia/reoxygenation-induced endothelial cell injury by reducing reactive oxygen species.
- Inhibits inflammation and apoptosis induced by doxorubicin.
- Ameliorates diabetic polyneuropathy and enhances pancreatic β-cell volume and insulin secretion.
- Attenuates myocardial hypertrophy, injury, and inflammatory response in diabetic models.
- Prevents obesity and obesity-related manifestations by boosting energy expenditure.
Chem-Impex International, Inc. 4-(3-Phenylpropyl)piperidine | 18495-82-4 | MFCD00023152 | 5G
4-(3-Phenylpropyl)piperidine, 18495-82-4, MFCD00023152, 5G
Chem-Impex International, Inc. Thiazol-2-yl-methylamine dihydrochloride | 55661-33-1 | MFCD09817422 | 5G
Thiazol-2-yl-methylamine dihydrochloride, 55661-33-1, MFCD09817422, 5G
eMolecules 221095-80-3 | AZETIDIN-3-YLMETHANAMINE 2HCL | AstaTech | MFCD10565803 | 159.050 | C4H12Cl2N2 | 95.000 | Cl.Cl.NCC1CNC1 | 0.25g | 233621883
AZETIDIN-3-YLMETHANAMINE 2HCL | AstaTech | 221095-80-3 | MFCD10565803 | 159.050 | C4H12Cl2N2 | 95.000 | Cl.Cl.NCC1CNC1 | 0.25g | 233621883
eMolecules 51420-71-4 | ChemScene | 57-Dimethyl-18-naphthyridin-2-ol | 100mg | 795362620 | CS-0331917 | MFCD00066907 | 174.203 | C10H10N2O
ChemScene | 57-Dimethyl-18-naphthyridin-2-ol | 100mg | 795362620 | CS-0331917 | 51420-71-4 | MFCD00066907 | 174.203 | C10H10N2O
Medchemexpress LLC Taniborbactam (hydrochloride) | 2244235-49-0 | 100.0% | 462.18 | 50 MG
Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. It is active against Gram-negative bacteria and effective against various β-lactamases, including KPC-2, AmpC, OXA-48, and VIM-2. This product is for research use only.
- Reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor.
- Active against gram-negative bacteria.
- Effective against KPC-2, AmpC, OXA-48, and VIM-2 β-lactamases.
- Demonstrated efficacy in neutropenic mouse lung infection and urinary tract infection models.
- Used in combination with cefepime or meropenem for enhanced activity against NDM-1-producing clinical isolates.
- Available documentation includes datasheet, COA, SDS, HNMR, and RP-HPLC.
- For research use only.
Medchemexpress LLC Etelcalcetide (hydrochloride) | 1334237-71-6 | 87645 | 99.3% | 1353.33 | 25 MG
Etelcalcetide hydrochloride is a synthetic calcimimetic that acts as an activator of the calcium sensing receptor (CaSR). It is effective in lowering parathyroid hormone (PTH) concentrations in dialysis patients with secondary hyperparathyroidism undergoing hemodialysis, showing promise for research in secondary hyperparathyroidism and chronic kidney disease.
- Activates the calcium sensing receptor (CaSR)
- Lowers parathyroid hormone (PTH) concentrations
- Effective for secondary hyperparathyroidism in dialysis patients
- Useful for research in secondary hyperparathyroidism and chronic kidney disease
- Reduces parathyroid hormone (PTH) levels in human parathyroid cells in vitro
- Significantly reduces plasma parathyroid hormone (PTH) concentrations in vivo
Medchemexpress LLC Nls (pkkkrkv) (hydrochloride) | 99.0% | 919.60 | 25 MG
NLS (PKKKRKV) hydrochloride is the hydrochloride form of NLS (PKKKRKV). It is a nuclear localization signal (NLS) derived from the simian virus 40 large tumor antigen (SV40 large T antigen). This signal mediates the binding of karyophilic protein to importin α and can enhance nuclear entry in gene transfer research.
- Derived from simian virus 40 large tumor antigen (SV40 large T antigen).
- Mediates binding of the karyophilic protein to importin α.
- Enhances nuclear entry in gene transfer research.
- Appearance: Solid.
- Color: White to off-white.
- Sequence: Pro-Lys-Lys-Lys-Arg-Lys-Val.
Cayman Chemical 2Aminomethylpyrimidine hydro
A synthetic intermediate useful for pharmaceutical synthesis.
eMolecules 50329-87-8 | 4-(4-Methoxyphenyl)piperidin-4-ol | Combi-Blocks | MFCD05237200 | 207.273 | C12H17NO2 | 95.000 | COc1ccc(cc1)C1(O)CCNCC1 | 1g | 439374057
4-(4-Methoxyphenyl)piperidin-4-ol | Combi-Blocks | 50329-87-8 | MFCD05237200 | 207.273 | C12H17NO2 | 95.000 | COc1ccc(cc1)C1(O)CCNCC1 | 1g | 439374057