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Aralkylamines

Organic compounds that consist of an alkylamine in which the alkyl group is substituted by an aromatic functional group.

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eMolecules​ Potassium (1-Boc-4-piperidinyloxy)methyltrifluoroborate | 1364936-24-2 | MFCD11505932 | 1g

Combi-Blocks | Potassium (1-Boc-4-piperidinyloxy)methyltrifluoroborate | 1g | 439374590 | QC-4427 | 97.000 | 1364936-24-2 | MFCD11505932 | 321.190 | C11H20BF3KNO3

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2

Medchemexpress LLC Amitriptyline hydrochloride | 549-18-8 | MFCD00012537 | 99.9% | 1 ML
SDP

Amitriptyline hydrochloride is an orally active tricyclic antidepressant primarily blocking SERT and NET, which elevates 5-hydroxytryptamine and norepinephrine in the synaptic cleft. It also functions as an α2A and TrkA/TrkB receptor agonist, providing analgesic and neurotrophic benefits by inhibiting cell apoptosis. This compound can reduce inflammation, angiogenesis, and fibrosis. It binds to DAT and various other receptors, while also capable of blocking sodium and hERG potassium channels.

  • Primarily blocks SERT and NET
  • Increases 5-hydroxytryptamine and norepinephrine in synaptic cleft
  • Acts as α2A and TrkA/TrkB receptor agonist
  • Provides analgesic and neurotrophic activities
  • Inhibits cell apoptosis
  • Reduces inflammation, angiogenesis, and fibrosis
  • Binds to DAT and multiple cholinergic, H1, and adrenergic receptors
  • Can block sodium and hERG potassium channels
  • For research use only

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3

Medchemexpress LLC Amitriptyline hydrochloride | 549-18-8 | 99.9% | 5 G
SDP

Amitriptyline hydrochloride is an orally active tricyclic antidepressant (TCA). It primarily exerts its antidepressant effect by blocking SERT and NET, which increases the concentrations of 5-hydroxytryptamine (5-HT) and norepinephrine (NE) in the synaptic cleft. It also acts as an agonist at α2A and TrkA/TrkB receptors, providing analgesic and neurotrophic activities. Amitriptyline hydrochloride can reduce inflammation, angiogenesis, and fibrosis.

  • Orally active tricyclic antidepressant (TCA)
  • Blocks SERT and NET, increasing 5-HT and NE concentrations
  • Agonist at α2A and TrkA/TrkB receptors
  • Provides analgesic and neurotrophic activities
  • Can reduce inflammation, angiogenesis, and fibrosis
  • Binds to DAT and antagonizes muscarinic, H1, and adrenergic α1 receptors
  • Can block sodium channels and hERG potassium channel

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