Azo compounds
Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 10 MG
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM). It is intended for research use only. This compound has been shown to reduce apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibit protein synthesis.
- Selective and high-affinity AhR agonist
- Ki of 0.2 nM
- No effect on estrogen receptor (Ki >100000 nM)
- Reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells
- Inhibits protein synthesis
- Intended for research use only
Medchemexpress LLC CAY 10465 50mg | 688348-33-6 | 98.3% | 317.13 | 50 MG
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
- Is a selective and high-affinity AhR receptor agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
- Reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells, and inhibits the synthesis of the protein (0.01 nM-100 μM).
TARGETMOL CHEMICALS INC KW-2449 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KW-2449 is a multiple-targeted inhibitor mostly for Flt3 (IC50 6.6 nM) modestly effective to Bcr-Abl FGFR1 and Aurora A; little inhibitory on PDGFR(beta) IGF-1R EGFR. purity: 99%
Sigma Aldrich Fine Chemicals Biosciences Naphthol Blue Black BioReagent, suitable for electrophoresis | 1064-48-8 | MFCD00004017 | 100G
Naphthol Blue Black BioReagent, suitable for electrophoresis | Mol Wt: 616.49 | 1064-48-8 | MFCD00004017 | 100G
TARGETMOL CHEMICALS INC DIAMIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Diamide is a reagent used as a thiol oxidizing agentpurity: 100%
Sigma Aldrich Fine Chemicals Biosciences Amido Black Staining Solution 2X1064-48-8 | MFCD00004017
Amido Black Staining Solution 2X | MW:616.49 | 1064-48-8 | MFCD00004017
Sigma Aldrich Fine Chemicals Biosciences Naphthol Blue Black | 1064-48-8 | MFCD00004017 | 25g
Naphthol Blue Black | Purity: 80 % | MW:616.49 | 1064-48-8 | MFCD00004017 | 25g
Ambeed N1 N1 N2 N2Tetramethyldiazene1
N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide, 10465-78-8, 97%
![Medchemexpress LLC {4-[(E)-2-(1H-indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol⁻¹ | C20H20N4O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244741.png-250.jpg)
Medchemexpress LLC {4-[(E)-2-(1H-indazol-3-yl)vinyl]phenyl}(1-piperazinyl)methanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol⁻¹ | C20H20N4O | 1 ML
KW-2449 is a multi-targeted small-molecule kinase inhibitor active against FLT3, ABL (including ABL T315I), and Aurora kinases. It exhibits low-nanomolar potency and is supplied for laboratory research use.
- Multi-targeted kinase inhibitor effective against FLT3, ABL, and Aurora kinases.
- Low-nanomolar potency with reported IC50s of 6.6, 14, 4, and 48 nM (FLT3, ABL, ABL T315I, Aurora).
- Provided as a 10 mM solution in DMSO (1 mL) or as a solid in multiple milligram sizes.
- High purity suitable for research (reported purity 99.9%).
- Molecular formula C20H20N4O; molecular weight 332.40 g·mol⁻¹.
- For research use only; not for human or veterinary use.
![Medchemexpress LLC [4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol-1 | C20H20N4O | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244548.png-250.jpg)
Medchemexpress LLC [4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone | 1000669-72-6 | MFCD18385006 | 99.9% | 332.40 g·mol-1 | C20H20N4O | 100 MG
KW-2449 is a small-molecule, multi-targeted kinase inhibitor used in research to study signaling pathways and leukemia models. Supplied as a high-purity white powder, it is characterized by the molecular formula C20H20N4O and a molecular weight of 332.40 g·mol-1.
- Multi-targeted kinase inhibition: inhibits FLT3, ABL, ABL T315I, and Aurora kinases at low nanomolar IC50s.
- High purity: reported 99.91% purity suitable for biochemical and cell-based assays.
- Solid powder form: convenient for dissolution in common organic solvents and buffers.
- Well-characterized: SMILES and molecular properties available for computational and analytical use.
- For research use only: not intended for human or clinical use.
Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 100 MG
CAY 10465 is a selective and high-affinity Aryl Hydrocarbon Receptor (AhR) agonist, with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). In vitro, CAY 10465 (at concentrations from 0.01 nM to 100 μM) has been shown to reduce apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibit the synthesis of this protein.
- Selective AhR agonist: High affinity for AhR with a Ki of 0.2 nM.
- No estrogen receptor effect: Shows no activity on the estrogen receptor (Ki >100000 nM).
- Inhibits apolipoprotein A-I: Reduces apo A-I levels and inhibits its synthesis in HepG2 cells.
- Appearance: Solid, white to off-white.
- Storage:
Powder: -20°C for 3 years, 4°C for 2 years.
In solvent: -80°C for 2 years, -20°C for 1 year.
Cambridge Isotope Laboratories 2 4 4 6-TetraBDE (BDE-75) (unlabeled) 50 ug/mL in nonane 1 2 mL
2 4 4 6-TetraBDE (BDE-75) (unlabeled) 50 ug/mL in nonane 1 2 mL