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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370853 APG-2449 5MG
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eMolecules 61551-69-7 | 2,2'-Azobis[2-methyl-n-(2-hydroxyethyl)propionamide] | Combi-Blocks, Inc. | MFCD00142728 | 288.348 | C12H24N4O4 | 98.000 | CC(C)(\N=N\C(C)(C)C(=O)NCCO)C(=O)NCCO | 25g | 818522541
2,2'-Azobis[2-methyl-n-(2-hydroxyethyl)propionamide] | Combi-Blocks, Inc. | 61551-69-7 | MFCD00142728 | 288.348 | C12H24N4O4 | 98.000 | CC(C)(\N=N\C(C)(C)C(=O)NCCO)C(=O)NCCO | 25g | 818522541
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 61551-69-7 | 2,2'-Azobis[2-methyl-n-(2-hydroxyethyl)propionamide] | Combi-Blocks, Inc. | MFCD00142728 | 288.348 | C12H24N4O4 | 98.000 | CC(C)(\N=N\C(C)(C)C(=O)NCCO)C(=O)NCCO | 5g | 818522540
2,2'-Azobis[2-methyl-n-(2-hydroxyethyl)propionamide] | Combi-Blocks, Inc. | 61551-69-7 | MFCD00142728 | 288.348 | C12H24N4O4 | 98.000 | CC(C)(\N=N\C(C)(C)C(=O)NCCO)C(=O)NCCO | 5g | 818522540
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Apexbio Technology LLC KW 2449 1000669-72-6 10mg
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KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
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Medchemexpress LLC CAY 10465 50mg | 688348-33-6 | 98.3% | 317.13 | 50 MG
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CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
- Is a selective and high-affinity AhR receptor agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).
- Reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells, and inhibits the synthesis of the protein (0.01 nM-100 μM).
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Apexbio Technology LLC KW 2449 1000669-72-6 10mM (in 1mL DMSO)
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
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Medchemexpress LLC KW-2449 | 1000669-72-6 | 99.9% | 332.40 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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KW-2449 is a multi-targeted kinase inhibitor that targets FLT3, ABL, ABLT315I, and Aurora kinase with IC50 values of 6.6, 14, 4, and 48 nM, respectively. It is intended for research use only.
- Targets FLT3, ABL, ABLT315I, and Aurora kinase.
- Exhibits antiproliferative activity against imatinib-resistant K562 cells.
- Inhibits FLT3-mediated STAT5 phosphorylation.
- Increases G1 phase cells and promotes apoptosis.
- Suppresses tumor growth in FLT3-mutated xenograft models.
- Helps release imatinib resistance.
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Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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CAY 10465 is a selective and high-affinity Aryl Hydrocarbon Receptor (AhR) agonist, with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). In vitro, CAY 10465 (at concentrations from 0.01 nM to 100 μM) has been shown to reduce apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibit the synthesis of this protein.
- Selective AhR agonist: High affinity for AhR with a Ki of 0.2 nM.
- No estrogen receptor effect: Shows no activity on the estrogen receptor (Ki >100000 nM).
- Inhibits apolipoprotein A-I: Reduces apo A-I levels and inhibits its synthesis in HepG2 cells.
- Appearance: Solid, white to off-white.
- Storage:
Powder: -20°C for 3 years, 4°C for 2 years.
In solvent: -80°C for 2 years, -20°C for 1 year.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM). It is intended for research use only. This compound has been shown to reduce apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibit protein synthesis.
- Selective and high-affinity AhR agonist
- Ki of 0.2 nM
- No effect on estrogen receptor (Ki >100000 nM)
- Reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells
- Inhibits protein synthesis
- Intended for research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 61551-69-7 | 2,2'-Azobis[2-methyl-n-(2-hydroxyethyl)propionamide] | Combi-Blocks, Inc. | MFCD00142728 | 288.348 | C12H24N4O4 | 98.000 | CC(C)(\N=N\C(C)(C)C(=O)NCCO)C(=O)NCCO | 500g | 818522543
2,2'-Azobis[2-methyl-n-(2-hydroxyethyl)propionamide] | Combi-Blocks, Inc. | 61551-69-7 | MFCD00142728 | 288.348 | C12H24N4O4 | 98.000 | CC(C)(\N=N\C(C)(C)C(=O)NCCO)C(=O)NCCO | 500g | 818522543
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
5000370767 APG-2449 50MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
Medchemexpress LLC CAY 10465 | 688348-33-6 | 98.3% | 317.13 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More
CAY 10465 is a selective and high-affinity AhR agonist with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). This compound reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibits the synthesis of the protein.
- Selective and high-affinity AhR agonist
- No effect on estrogen receptor
- Reduces apolipoprotein A-I levels in HepG2 cells
- Inhibits protein synthesis
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
Learn More
eMolecules 61551-69-7 | 2,2'-Azobis[2-methyl-n-(2-hydroxyethyl)propionamide] | Combi-Blocks, Inc. | MFCD00142728 | 288.348 | C12H24N4O4 | 98.000 | CC(C)(\N=N\C(C)(C)C(=O)NCCO)C(=O)NCCO | 100g | 818522542
2,2'-Azobis[2-methyl-n-(2-hydroxyethyl)propionamide] | Combi-Blocks, Inc. | 61551-69-7 | MFCD00142728 | 288.348 | C12H24N4O4 | 98.000 | CC(C)(\N=N\C(C)(C)C(=O)NCCO)C(=O)NCCO | 100g | 818522542
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Ambeed AMBEED
5000883023 2446-TETRABROMO-25-CYCLO 10G
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 27776-21-2 | 2,2-Azobis[2-(2-Imidazolin-2-yl)Propane] Dihydrochloride | AA Blocks LLC | MFCD00142723 | 323.270 | C12H24Cl2N6 | 0.000 | Cl.Cl.CC(C)(\N=N\C(C)(C)C1=NCCN1)C1=NCCN1 | 25g | 518488852
2,2-Azobis[2-(2-Imidazolin-2-yl)Propane] Dihydrochloride | AA Blocks LLC | 27776-21-2 | MFCD00142723 | 323.270 | C12H24Cl2N6 | 0.000 | Cl.Cl.CC(C)(\N=N\C(C)(C)C1=NCCN1)C1=NCCN1 | 25g | 518488852
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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