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Nitrogen mustards are cytotoxic organic compounds with the chloroethylamine functional group, which consists of the following structure: Cl(CH2)2NR2, where R can be any organic group. They are nitrogen analogs of mustard gas.
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Flesinoxan is a selective 5-HT1A receptor agonist research compound intended for laboratory research use. It is supplied as an off-white to light yellow solid with demonstrated potency at the 5-HT1A receptor and standard handling and storage recommendations for small-molecule research chemicals.
Selective 5-HT1A receptor agonist (EC50 24 nM).
High reported purity: 99.9%.
Off-white to light yellow solid appearance.
Soluble in DMSO (31.25 mg/mL); in vivo formulations reported at ≥2.08 mg/mL.
Storage: powder stable at -20°C (3 years) and 4°C (2 years).
For research use only; not for human consumption or clinical use.
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VIT-2763 is an oral ferroportin inhibitor designed to inhibit hepcidin binding to ferroportin and block iron efflux. It holds potential for treating β-thalassemia by addressing iron regulation. This compound has demonstrated significant biological activity both in vitro and in vivo.
Reduces fluorescence polarization signal by displacing TMR-hepcidin from ferroportin.
Induces BLA reporter gene activity, increasing intracellular iron concentrations by blocking iron export.
Triggers ubiquitination and degradation of ferroportin.
Corrects anemia and improves red blood cell parameters in relevant animal models.
Decreases the percentage of ROS-positive red blood cells and extends their lifespan.
Significantly decreases serum iron levels in animal studies.
Currently undergoing Phase 2 clinical trials for Beta-Thalassemia and Sickle Cell Disease.
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3-(9-fluorenylmethoxycarbonylamido)-tricyclo[3.3.1.1(3.7)]decane-1-carboxylic acid is a Amino Acid reagent (Subcategory: Alkane AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications - CAS: 875211-10-2 - MDL: No data - InChIKey: RXRDRSUDCSEVRK-UHFFFAOYSA-N - Molecular Weight: 417.505 - Molecular Formula: C26H27NO4 - Purity: ≥95% - Container Type: 250 mL HDPE - Pack Size: 50 g - Net Weight: 50 g - Gross Weight: 89.8 g - Commodity Code: 29242970 - Country Of Origin: China - IUPAC: 3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)adamantane-1-carboxylic acid - SMILES: OC(C12CC3CC(C2)CC(C1)(NC(OCC4C5=CC=CC=C5C6=CC=CC=C46)=O)C3)=O
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More