Alcohols and polyols
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- (1)
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- (10)
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- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (61)
- (13)
- (14)
- (1)
- (2)
- (1)
- (26)
- (6)
- (4)
- (1)
- (6)
- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
- (7)
- (10)
- (145)
- (114)
- (6)
- (5)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (2)
- (4)
- (1)
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- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (2)
- (5)
- (4)
- (33)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (17)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (2)
- (10)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (1)
- (5)
- (3)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
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- (2)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (2)
- (1)
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- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (1)
- (2)
- (8)
- (2)
- (3)
- (3)
- (8)
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- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
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- (1)
- (1)
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- (1)
- (5)
- (12)
- (9)
- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
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- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
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- (16)
- (1)
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- (20)
- (2)
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- (67)
- (1)
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![Medchemexpress LLC Benzoic acid, 2-[4-[2-(1-piperidinyl)ethoxy]benzoyl]-, methyl ester, hydrochloride (1:1) | 1248-42-6 | 99.9% | 403.90 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Benzoic acid, 2-[4-[2-(1-piperidinyl)ethoxy]benzoyl]-, methyl ester, hydrochloride (1:1) | 1248-42-6 | 99.9% | 403.90 | 25 MG
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Pitofenone hydrochloride is a spasmolytic compound that inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and electric eel with Kis of 36 and 45 μM, respectively. It also exhibits anticonvulsant activity when combined with diclofenac and fenpivirine.
- Spasmolytic compound
- Inhibits acetylcholinesterase (AChE) activity
- Anticonvulsant activity in combination with diclofenac and fenpivirine
- Appearance: Solid
- Color: White to off-white
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Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 1 MG
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CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 (G protein-coupled receptor kinase 2) inhibitor (IC50=30 nM). It exhibits 230-fold selectivity over GRK5 and more than 2500-fold selectivity over GRK1, PKA, and ROCK1. This compound can be utilized in heart failure research.
- Potent and selective GRK2 inhibitor (IC50=30 nM).
- Exhibits 230-fold selectivity over GRK5 (IC50=7.09 μM) and more than 2500-fold selectivity over GRK1 (IC50=87.3 μM), PKA, and ROCK1.
- Applicable in heart failure research.
- Significant improvement in βAR-stimulated contractility in mouse cardiomyocytes at concentrations as low as 0.1 μM.
- Superior half-life in vivo with total plasma drug levels exceeding the GRK2 IC50 for seven hours after a single intraperitoneal administration of 10 mg/kg in CD-1 mice.
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Medchemexpress LLC Flavoxate hydrochloride (Standard) | 3717-88-2 | 99.7% | 100 MG
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Flavoxate hydrochloride (Standard) | 3717-88-2 | 99.7% | 100 MG
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eMolecules Chem-Impex Di-tert-butyl pyrocarbonate 10kg 342448878 00128 0 000 24424-99-5 MFCD00008805 218 249 C10H18O5
Chem-Impex Di-tert-butyl pyrocarbonate 10kg 342448878 00128 0 000 24424-99-5 MFCD00008805 218 249 C10H18O5
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Medchemexpress LLC tert-Butyl 6-bromohexanoate | 65868-63-5 | 99.7% | 251.16 | 100 G
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tert-Butyl 6-bromohexanoate is a PROTAC linker that can be used to design PROTACs.
- PROTAC linker
- Used to design PROTACs
- For research use only
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Medchemexpress LLC 2-Phenylethyl isothiocyanate (2-PE ITC) | 2257-09-2 | 98.00% | 163.24 | 100 MG
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2-Phenylethyl isothiocyanate is a potent antifungal agent that significantly inhibits spore germination and mycelial growth of *Alternaria alternata* with a minimum inhibitory concentration (MIC) of 1.22 mM. Its antifungal effect against *Alternaria alternata* may involve reducing toxin content and breaking down cell membrane integrity.
- Significantly inhibited spore germination.
- Significantly inhibited mycelial growth.
- Reduces toxin content.
- Breaks down cell membrane integrity.
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Medchemexpress LLC Tert-butyl 2,2-dimethyl-5-oxopiperidine-1-carboxylate | 1894533-96-0 | MFCD31718688 | 97.0% | 227.30 g·mol⁻¹ | C12H21NO3 | 1 G
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tert-Butyl 2,2-dimethyl-5-oxopiperidine-1-carboxylate (CAS 1894533-96-0) is a tert-butyl-protected oxopiperidine derivative used as a building block and drug intermediate in medicinal chemistry research. It is provided in laboratory quantities for use in small-scale synthesis, with characterized purity and recommended storage conditions for long-term stability.
- Used as a drug intermediate in small-scale synthesis.
- Provides tert-butyl protection for piperidinone derivatives.
- Molecular formula C12H21NO3; molecular weight 227.30 g·mol⁻¹.
- Typical supplied purity is about 97.0%.
- Stable at room temperature for long-term storage when dry.
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Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 100.0% | 362.30 | 50 MG
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Clemizole hydrochloride is an H1 histamine receptor antagonist that has been shown to substantially inhibit HCV replication. It also acts as an inhibitor of the TRPC5 channel. The IC50 of Clemizole hydrochloride for RNA binding by NS4B is 24 nM, while its EC50 for viral replication is 8 μM.
- Inhibits HCV RNA replication in cell culture.
- Suppresses NS4B's RNA binding.
- Offers minimal host cell toxicity.
- Functions as a novel inhibitor of TRPC5 channels.
- Efficiently blocks TRPC5 currents and Ca2+ entry in the low micromolar range.
- Exhibits six-fold selectivity for TRPC5 over TRPC4β.
- Displays almost 10-fold selectivity over TRPC3 and TRPC6.
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Medchemexpress LLC Trazodone (hydrochloride) | 25332-39-2 | 99.6% | 50 MG
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This product is a triazolopyridine derivative, classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It demonstrates antidepressant and anti-insomnia activities by antagonizing α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. It is intended for research use only.
- Classified as a serotonin receptor antagonist and reuptake inhibitor (SARI)
- Exhibits antidepressant and anti-insomnia activity
- Antagonizes α1- and α2-adrenergic receptors
- Antagonizes histamine H1 receptors
- Minimal anticholinergic effects
- Purity of 99.60%
- Molecular formula: C19H23Cl2N5O
- Appears as a white to off-white solid
- Soluble in DMSO and water
- Binds to 5-HT1A receptor with high affinity
- Inhibits key signaling pathways for neuroinflammatory markers
- Increases BDNF and CREB expression
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eMolecules Ambeed / 2-Methoxyethyl chloride / 5g / 490564858 / A541311 / / 627-42-9 / MFCD00000972 / 94.540 / C3H7ClO
Ambeed / 2-Methoxyethyl chloride / 5g / 490564858 / A541311 / / 627-42-9 / MFCD00000972 / 94.540 / C3H7ClO
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Medchemexpress LLC Trazodone (hydrochloride) | 25332-39-2 | 99.6% | 100 MG
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Trazodone (hydrochloride) is a triazolopyridine derivative that acts as a serotonin receptor antagonist and reuptake inhibitor (SARI). It exhibits antidepressant and anti-insomnia activity, alongside antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. This product is intended for use as a laboratory chemical and for substance manufacturing, and is stable under recommended storage conditions.
- Triazolopyridine derivative
- Serotonin receptor antagonist and reuptake inhibitor (SARI)
- Demonstrates antidepressant and anti-insomnia activity
- Exhibits antagonistic properties against α1- and α2-adrenergic and histamine H1 receptors
- Minimal anticholinergic effects
- Stable under recommended storage conditions
- For research use only
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Medchemexpress LLC Fendiline (hydrochloride) | 13636-18-5 | 99.8% | 1 ML
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Fendiline hydrochloride is a diphenylalkylamine type of antianginal agent that acts as an L-type calcium channel blocker with an IC50 of 17 μM. It is also identified as a selective K-Ras inhibitor, showing no effect on H-Ras and N-Ras. It inhibits K-Ras plasma membrane localization (IC50 of 9.64 μM) and K-Ras signal output. Additionally, Fendiline hydrochloride is a STING agonist and has demonstrated the ability to inhibit the growth of multiple refractory cold tumors. This product is provided as a 10 mM solution in 1 mL of DMSO with a purity of 99.78%.
- Acts as an L-type calcium channel blocker
- Functions as a selective K-Ras inhibitor
- Inhibits K-Ras plasma membrane localization
- Suppresses K-Ras signal output
- Prevents proliferation of various cancer cell lines
- Serves as a STING agonist
- Inhibits growth of refractory cold tumors
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Medchemexpress LLC Ponatinib hydrochloride | 1114544-31-8 | 99.8% | 569.02 | 25 MG
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Ponatinib hydrochloride, also known as AP24534 hydrochloride, is an orally active multi-targeted kinase inhibitor. It inhibits various kinases with IC50s including 0.37 nM for Abl, 1.1 nM for PDGFRα, 1.5 nM for VEGFR2, 2.2 nM for FGFR1, and 5.4 nM for Src.
- Purity of 99.76%
- CAS number: 1114544-31-8
- Molecular weight: 569.02
- Appears as an off-white to light yellow solid
- Soluble in DMSO at 25 mg/mL
- Targets Bcr-Abl, FGFR, PDGFR, VEGFR, Src, and Autophagy pathways
- Store at 4°C, sealed, away from moisture; in solvent, store at -80°C for 6 months or -20°C for 1 month
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Sigma Aldrich Fine Chemicals Biosciences Hexyl alcohol FCC FG170KG
Hexyl alcohol FCC FG170KG
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eMolecules EMOLECULES INC
5000490015 TERT-BUTYL 4-BROMOBENZOATE 10G
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