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Filtered Search Results
Medchemexpress LLC Luxeptinib | 1616428-23-9 | 99.0% | 495.43 | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Luxeptinib (CG-806) is an orally active, reversible, first-in-class, non-covalent and potent pan-FLT3/pan-BTK inhibitor. It induces cell cycle arrest, apoptosis, or autophagy in acute myeloid leukemia cells.
- Inhibits proliferation of MEC-1 CLL cells with an IC50 of 32 nM.
- Suppresses SYK phosphorylation in primary chronic lymphocytic leukemia (CLL) cells.
- Completely inhibits phosphorylation of FLT3 and STAT5 in MV4-11 cells.
- Undergoing phase 1 clinical trials for chronic lymphocytic leukemia, small lymphocytic lymphoma, and non-Hodgkin´s lymphoma.
- Undergoing phase 1 clinical trials for acute myeloid leukemia and myelodysplastic syndromes.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 106961-22-2 | 1,4,7,17,20,23-HEXAAZA-CYCLODOTRIACONTANE 6HCL | AstaTech | MFCD05863898 | 673.540 | C26H64Cl6N6 | 97.000 | Cl.Cl.Cl.Cl.Cl.Cl.C1CCCCNCCNCCNCCCCCCCCCNCCNCCNCCCC1 | 1g | 112530030
1,4,7,17,20,23-HEXAAZA-CYCLODOTRIACONTANE 6HCL | AstaTech | 106961-22-2 | MFCD05863898 | 673.540 | C26H64Cl6N6 | 97.000 | Cl.Cl.Cl.Cl.Cl.Cl.C1CCCCNCCNCCNCCCCCCCCCNCCNCCNCCCC1 | 1g | 112530030
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 6-phenylimidazo[2,1-b]thiadiazole-2-sulfonamide | 63735-71-7 | MFCD02064987 | 99.8% | 280.33 g·mol⁻1 | C10H8N4O2S2 | 5 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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AEG3482 is a small-molecule JNK inhibitor used in research to probe apoptosis and stress-response signaling. It binds Hsp90, promotes HSF1-dependent induction of heat shock proteins such as Hsp70 and Hsp25, and shows antiapoptotic activity in cellular and in vivo models. Supplied as a solid for laboratory use, it is intended for research only.
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eMolecules 1149-23-1 | Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate | Accela ChemBio (ASD) | MFCD00005951 | 253.298 | C13H19NO4 | 95.000 | CCOC(=O)C1=C(C)NC(C)=C(C1)C(=O)OCC | 100g | 444750662
Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate | Accela ChemBio (ASD) | 1149-23-1 | MFCD00005951 | 253.298 | C13H19NO4 | 95.000 | CCOC(=O)C1=C(C)NC(C)=C(C1)C(=O)OCC | 100g | 444750662
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Medchemexpress LLC 1-Pentadecanol | 629-76-5 | 228.41 | 100 G
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1-Pentadecanol is a long-chain fatty alcohol known for its anti-comedone activity and its moisturizing and hydrating properties, making it suitable for skin care product formulations. It also finds applications in the production of surfactants, emulsifiers, and lubricants. This product is intended for research use only and is not for patient administration.
- Long-chain fatty alcohol
- Exhibits anti-comedone activity
- Moisturizing and hydrating properties
- Suitable for skin care product formulations
- Utilized in surfactant production
- Utilized in emulsifier production
- Utilized in lubricant production
- For research use only
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Medchemexpress LLC KY-556 | 110816-78-9 | 725.57 | 5 MG
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KY-556 is a promising and orally-active pro-agent of disodium cromoglycate (DSCG) against allergic diseases.
- Inhibits 48-hr homologous passive cutaneous anaphylaxis (PCA) in rats dose-dependently with a longer duration of action compared to intravenous Disodium cromoglycate (DSCG).
- Tends to inhibit histamine release from actively sensitized rat lung fragments.
- Shows prolongation of survival time in rat systemic anaphylaxis.
- Significantly inhibits increased airway resistance in experimental asthma in rats.
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Sigma Aldrich Fine Chemicals Biosciences 3-Phenyl-1-propanol >=98%, FCC | 122-97-4 | MFCD00002950 |
3-Phenyl-1-propanol >=98%, FCC | Purity: >=98% | Mol Wt: 136.19 | 122-97-4 | MFCD00002950 |
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Medchemexpress LLC Platyconic acid A | 68051-23-0 | 99.1% | 1239.31 | 5 MG
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Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation.
- Inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner.
- Decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner.
- Stored at 4°C, protected from light.
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light.
- Soluble in H2O at 25 mg/mL (20.17 mM) with ultrasonic assistance.
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Selleck Chemical LLC ESBA 105-A3098-1MG-25
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ESBA 105 is an antibody targeting tumor necrosis factor (TNF) It has an efficient intraocular penetration to anterior and posterior region of eye MW 145 14 KD
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Medchemexpress LLC 3-(6-chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane hydrochloride | 2414674-71-6 | 99.4% | C11H14Cl2N2O | 10MG
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This small-molecule hydrochloride is a potent, selective, brain-penetrant, and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist with a reported Ki ≈ 1.5 nM and demonstrated antidepressant activity in preclinical models. It is described in the literature and supplier listings as a crystalline, non-hygroscopic salt with favorable ADME and safety properties.
- Potent, selective α4β2 receptor antagonism (Ki ≈ 1.5 nM).
- Oral bioavailability and brain penetration demonstrated in preclinical studies.
- Favorable ADME profile with low drug-drug interaction liability.
- Crystalline hydrochloride salt with stable physicochemical properties.
- Reported high purity in supplier analyses (example: 99.4%).
- Supported by published preclinical studies and supplier data.
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Medchemexpress LLC MS-444 | 150045-18-4 | 98.75% | 230.22 | 5 MG
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MS-444 is an inhibitor of purified smooth muscle myosin light chain kinase (MLCK) with an IC50 value of 10 μM. It also functions as a small molecule RNA-binding protein HuR (ELAVL1) inhibitor, demonstrating growth inhibition in colorectal cancer cells and anti-angiogenic potential in vivo. This product is for research use only and not intended for patient use.
- Inhibits smooth muscle myosin light chain kinase (MLCK) with an IC50 of 10 μM.
- Functions as a small molecule RNA-binding protein HuR (ELAVL1) inhibitor.
- Demonstrates growth inhibition in various colorectal cancer cell lines.
- Less responsive in non-transformed intestinal epithelial cells compared to cancer cells.
- Shows anti-tumor effects and reduces microvessel density in vivo in xenograft models.
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eMolecules 33036-62-3 | 4-Bromo-1-butanol, tech grade | Combi-Blocks, Inc. | MFCD00015387 | 153.019 | C4H9BrO | 80.000 | OCCCCBr | 500g | 761021226
4-Bromo-1-butanol, tech grade | Combi-Blocks, Inc. | 33036-62-3 | MFCD00015387 | 153.019 | C4H9BrO | 80.000 | OCCCCBr | 500g | 761021226
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Aobchem AOBCHEM
5000943296 1- 2-METHOXYPHENYL -1-PENTYN-3
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Medchemexpress LLC 1-Undecanol | 112-42-5 | 172.31 | 5 G
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1-Undecanol, also known as Undecyl alcohol, is a metabolite primarily produced from the degradation of 2-tridecanone by Pseudomonas bacteria found in soil. This compound has shown potential in enhancing the attraction of Grapholita molesta to sex pheromone traps. It appears as a solid below 11°C and a liquid above 11°C, with a colorless to light yellow appearance.
- Formula: C11H24O
- Initial source: Plants other families and microorganisms (a strain of Pseudomonas)
- Solubility: 100 mg/mL in DMSO (580.35 mM)
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- For research use only
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eMolecules 198561-07-8 | (S)-2-(Fmoc-amino)-4-pentynoic Acid | Accela ChemBio (ASD) | MFCD01075095 | 335.359 | C20H17NO4 | 98.000 | OC(=O)[C@H](CC#C)NC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 436036248
(S)-2-(Fmoc-amino)-4-pentynoic Acid | Accela ChemBio (ASD) | 198561-07-8 | MFCD01075095 | 335.359 | C20H17NO4 | 98.000 | OC(=O)[C@H](CC#C)NC(=O)OCC1c2ccccc2-c2ccccc12 | 5g | 436036248
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