Alcohols and polyols
Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.
Quantity
- (1)
- (55)
- (350)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
- (64)
- (29)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (6)
- (3)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (63)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (116)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
Molecular Weight (g/mol)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (1)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (2)
- (8)
- (2)
- (3)
- (3)
- (1)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (10)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (6)
- (1)
- (5)
- (5)
- (2)
- (1)
- (2)
- (1)
- (7)
- (2)
- (1)
- (1)
- (2)
- (7)
- (5)
- (1)
- (2)
- (5)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (4)
- (6)
- (9)
Percent Purity
- (4)
- (3)
- (2)
- (1)
- (4)
- (3)
- (2)
- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (82)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (22)
- (16)
- (1)
- (2)
- (21)
- (2)
- (2)
- (2)
- (1)
- (67)
- (1)
- (1)
- (1)
- (4)
- (8)
- (1)
- (2)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (9)
- (6)
- (8)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (6)
- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (86)
- (1)
- (5)
- (72)
- (3)
- (5)
- (238)
- (4)
- (2)
- (2)
- (21)
- (281)
- (17)
- (1)
- (6)
- (280)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
Physical Form
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (733)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
- (3)
- (3)
Boiling Point
- (4)
- (11)
- (3)
- (2)
- (1)
- (3)
- (2)
- (3)
- (2)
- (3)
- (1)
- (3)
- (6)
- (3)
- (2)
- (2)
- (2)
- (3)
- (7)
- (7)
- (1)
- (3)
- (2)
- (3)
- (3)
- (2)
- (1)
- (2)
- (3)
- (3)
- (1)
- (4)
- (3)
- (3)
- (6)
- (5)
- (6)
- (7)
- (3)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (6)
- (2)
- (1)
- (2)
- (2)
- (1)
- (4)
- (3)
- (4)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (9)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (1)
- (7)
- (2)
- (3)
- (2)
- (2)
- (6)
- (2)
- (4)
- (1)
- (11)
- (2)
- (2)
- (4)
- (6)
- (2)
- (4)
- (1)
- (1)
- (4)
- (8)
- (2)
- (3)
- (2)
- (13)
- (6)
- (2)
- (2)
- (14)
- (2)
- (3)
- (1)
- (2)
- (11)
- (1)
- (8)
- (2)
- (5)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (2)
- (12)
- (2)
- (2)
- (3)
- (4)
- (9)
- (3)
- (6)
- (3)
- (5)
- (2)
- (7)
- (2)
- (3)
- (12)
- (2)
- (3)
- (3)
- (3)
- (2)
- (5)
- (2)
- (11)
- (1)
- (3)
- (4)
- (1)
- (6)
- (4)
- (2)
- (4)
- (1)
- (2)
- (5)
- (2)
- (2)
- (6)
- (2)
- (2)
- (3)
- (2)
- (2)
- (7)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (2)
- (3)
- (3)
- (2)
- (2)
- (3)
- (5)
- (3)
- (2)
- (4)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (7)
- (4)
- (5)
- (3)
- (6)
- (3)
- (2)
- (1)
- (4)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (3)
- (4)
- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (6)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (3)
- (2)
- (5)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (4)
- (2)
- (2)
- (3)
- (3)
- (2)
- (3)
- (6)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (1)
- (12)
- (2)
- (10)
- (2)
- (1)
- (12)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (7)
- (3)
- (4)
- (3)
- (1)
- (4)
- (2)
- (3)
- (2)
- (7)
- (4)
- (4)
- (3)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (6)
- (1)
- (2)
- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (3)
- (1)
- (2)
- (8)
- (2)
- (5)
- (4)
- (1)
- (2)
- (2)
- (1)
- (4)
- (8)
- (3)
- (5)
- (2)
- (6)
- (4)
- (2)
- (2)
- (5)
- (6)
- (2)
- (2)
- (3)
- (3)
- (3)
- (2)
- (5)
- (1)
- (2)
- (3)
- (4)
- (1)
- (7)
- (1)
- (1)
- (3)
- (5)
- (2)
- (2)
- (3)
- (2)
- (3)
- (5)
- (4)
- (4)
- (1)
- (3)
- (2)
- (2)
- (2)
- (8)
- (3)
- (2)
- (2)
- (3)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (1)
- (2)
- (1)
- (7)
- (2)
- (2)
- (3)
- (3)
- (2)
- (1)
- (2)
- (2)
- (4)
- (3)
- (1)
- (4)
- (2)
- (6)
- (1)
- (6)
- (3)
- (2)
- (2)
- (2)
- (2)
- (13)
- (7)
- (6)
- (5)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (2)
- (3)
- (2)
- (5)
- (4)
- (3)
- (2)
- (4)
- (2)
- (2)
- (6)
- (3)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (3)
- (2)
- (3)
- (1)
- (1)
- (5)
- (1)
- (1)
- (3)
- (5)
- (2)
- (1)
- (2)
- (1)
- (2)
- (2)
- (1)
- (2)
- (3)
- (2)
- (1)
- (3)
- (1)
- (7)
- (2)
- (3)
- (5)
- (1)
- (2)
- (1)
- (2)
- (1)
- (7)
- (10)
- (2)
- (3)
- (1)
- (2)
- (14)
- (1)
- (3)
- (2)
- (2)
- (2)
- (4)
- (8)
- (2)
- (1)
- (3)
- (1)
- (7)
- (1)
- (9)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (2)
- (3)
- (3)
- (1)
- (3)
- (7)
- (4)
- (4)
- (4)
- (1)
- (5)
- (3)
- (2)
- (2)
- (1)
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5,551
Medchemexpress LLC PXS-5505 anhydrous (LOX-IN-3 dihydrochloride) | 2409964-23-2 | 99.9% | 353.24 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and Specialty Supplier Partner
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PXS-5505 anhydrous, also known as LOX-IN-3 dihydrochloride, is an orally active inhibitor of lysyl oxidase (LOX). This compound has potential applications in research related to fibrosis, cancer, and angiogenesis.
- Orally active lysyl oxidase inhibitor.
- Can be used for fibrosis research.
- Can be used for cancer research.
- Can be used for angiogenesis research.
- Inhibits human LOXL2 activity with an IC50 value of <1 μM.
- Inhibits bovine LOX activity with an IC50 value of <10 μM.
- Exhibits sustained inhibition of LOXL1 and LOXL2.
- Less active against SSAO/VAP-1 and MAO-B activities.
- Completely abolished lysyl oxidase activity in rats at 30 mg/kg orally.
- Reduces kidney fibrosis in unilateral ureteric obstruction (UUO) mice model at 10 mg/kg orally.
- Reduces lung fibrosis in mice at 15 mg/kg orally in a bleomycin-induced model.
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5,552
Ambeed 4Formylbenzonitrile
4-Formylbenzonitrile, 105-07-7, 97%
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5,553
Medchemexpress LLC 1-Nonadecanol | 1454-84-8 | 284.52 | 5 G
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Small and Specialty Supplier Partner
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1-Nonadecanol is a chemical compound found as a component of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii and as an important aroma compound in Neotinea ustulata. It appears as a white to off-white solid.
- White to off-white solid appearance
- Purity of 99.2%
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 2 mg/mL (7.03 mM) with ultrasonic, warming, and heating to 60°C
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5,554
Medchemexpress LLC Slm6031434 hydrochloride | 1897379-34-8 | 99.1% | 5MG
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Slm6031434 hydrochloride | 1897379-34-8 | 99.1% | 5MG
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5,555
Medchemexpress LLC Amotosalen hydrochloride | 161262-45-9 | MFCD09970539 | 99.9% | 337.8 g/mol | C17H20ClNO4 | 1 ML
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Amotosalen hydrochloride is a light-activated psoralen compound that crosslinks DNA and RNA upon UVA exposure, used for pathogen inactivation studies and for research applications requiring covalent nucleic acid modification. Supplied as a 10 mM solution (1 mL) with high purity and documented handling information, it is intended for laboratory research use under appropriate safety protocols.
- Photoactivated crosslinking of DNA and RNA for pathogen inactivation studies.
- Supplied as a ready-to-use 10 mM solution for consistent dosing.
- High purity suitable for analytical and biological research applications.
- Well-characterized molecular properties for reproducible results.
- Includes SDS and datasheet documentation for safe handling and use.
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5,556
Medchemexpress LLC Ap-III-a4 hydrochloride | 2070014-95-6 | 99.9% | 631.18 g/mol | C31H44ClFN8O3 | 10 MG
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AP-III-a4 hydrochloride is a small-molecule, nonsubstrate analogue inhibitor of enolase supplied as the hydrochloride salt for research use. It is reported to bind and inhibit enolase (IC50 0.576 μM) and has been used in studies of cancer cell viability, migration, invasion, apoptosis, and glucose metabolism.
- Nonsubstrate analogue enolase inhibitor (IC50 0.576 μM).
- Used in cancer and diabetes research, including HCT116 cell assays.
- Shown to inhibit cell migration and invasion and to induce apoptosis.
- Increases glucose uptake and inhibits PEPCK expression in cell studies.
- Supplied as a hydrochloride solid suitable for laboratory assays, commonly available in small quantities such as 10 MG.
- Analytical documentation typically available (HPLC, LCMS, certificate of analysis).
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5,557
Medchemexpress LLC Voruciclib hydrochloride | 1000023-05-1 | 99.2% | 506.30 g·mol⁻1 | C22H20Cl2F3NO5 | 10MM 1ML
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Voruciclib hydrochloride is an orally active, selective cyclin-dependent kinase inhibitor that potently inhibits CDK9 and represses MCL-1 transcription; it is provided for research use in solution and solid formats for cellular and biochemical studies.
- Selectively inhibits CDK9 with low-nanomolar potency.
- Represses MCL-1 expression in cellular models.
- Supplied as a 10 mM solution in DMSO and in solid mass quantities.
- High purity suitable for research applications.
- Molecular weight 506.30 g·mol⁻1; formula C22H20Cl2F3NO5.
- Intended for use in cell biology and oncology research.
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5,558
Medchemexpress LLC AR-C102222 hydrochloride | 1781934-50-6 | 99.8% | 50 MG
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AR-C102222 hydrochloride is a selective inducible nitric oxide synthase (iNOS) inhibitor (IC50 = 37 nM) provided as the hydrochloride salt for research use. It exhibits reported antinociceptive and anti-inflammatory activity and is supplied as a high-purity solid suitable for in vitro and in vivo studies.
- Purity 99.83%.
- Molecular weight 418.83 g/mol.
- Chemical formula C19H17ClF2N6O.
- Soluble in DMSO (100 mg/mL); formulatable for in vivo dosing (≥5 mg/mL in recommended vehicles).
- Storage: 4°C sealed; in solvent store at -80°C (6 months) or -20°C (1 month).
- Available as solid in multiple sizes, including 50 mg.
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5,559
Medchemexpress LLC Ro 41-1049 hydrochloride | 127917-66-2 | MFCD00900596 | 100.0% | 301.77 g·mol⁻¹ | C12H13ClFN3OS | 1 ML
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Ro 41-1049 hydrochloride is a reversible, selective monoamine oxidase A (MAO-A) inhibitor supplied for research use. It is available as a solid and as a pre-made 10 mM solution in DMSO (1 mL), and is provided with a high reported purity to support reproducible in vitro experiments.
- Reversible, selective MAO-A inhibition suitable for biochemical assays.
- Supplied as solid or pre-made 10 mM solution in DMSO (1 mL) for convenience.
- High reported purity to reduce confounding impurities.
- Characterized by CAS number 127917-66-2 and known molecular weight for accurate dosing.
- Intended for research use only; not for human or clinical use.
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5,560
Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 25 MG
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Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. It inhibits estrogen production in hamster ovarian slices and has various in vivo effects, including the prevention of certain tumors and reduction of parasite burden.
- Potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.
- Inhibits estrogen production with an IC50 of 0.03 μM.
- Inhibits progesterone production with an IC50 of 120 μM.
- Inhibits aromatase-mediated uterine hypertrophy in immature female rats with an oral ED50 of 0.03 mg/kg.
- Prevents development of benign and malignant spontaneous mammary neoplasms.
- Slows spontaneous development of pituitary pars distalis adenomas.
- Reduces incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
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5,561
Medchemexpress LLC Vu6036720 hydrochloride | 3026597-12-3 | 99.7% | 473.39 | C20H23Cl2FN4O2S | 10 MG
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VU6036720 hydrochloride is the hydrochloride salt of a potent, selective in vitro inhibitor of heteromeric Kir4.1/5.1 inward-rectifier potassium channels, used for research into neural and renal channel function. The compound is supplied as a high-purity solid suitable for biochemical and electrophysiological assays.
- Potent Kir4.1/5.1 inhibition with IC50 0.24 μM.
- High purity suitable for research applications.
- Available in small solid quantities for assay workflows.
- Stable solid with recommended sealed storage at 4°C.
- Compatible with DMSO stock preparations for in vitro testing.
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5,562
Medchemexpress LLC Gyki 53655 (hydrochloride) | 143692-48-2 | 98.4% | 388.85 g·mol⁻¹ | C19H21ClN4O3 | 100 MG
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GYKI 53655 hydrochloride is a research-grade small molecule that acts as a non-competitive antagonist of AMPA and kainate receptors. It is supplied as a light yellow to yellow solid with reported purity of ~98.4% and molecular formula C19H21ClN4O3. Intended for in vitro research use only.
- Non-competitive AMPA and kainate receptor antagonist.
- High purity (~98.4%) for consistent experimental results.
- Light yellow to yellow solid, soluble in DMSO and water with recommended handling precautions.
- Recommended storage: solid at 4°C; prepared solutions at -80°C (up to 6 months) or -20°C (short term).
- Available in multiple solid sizes, including 100 mg, for lab-scale studies.
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5,563
Medchemexpress LLC Alpelisib hydrochloride | 1584128-91-5 | 99.6% | 477.93 g/mol | C19H23ClF3N5O2S | 10 MG
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Alpelisib hydrochloride is the hydrochloride salt of a selective PI3Kα inhibitor used in research to probe PI3K signaling and PIK3CA-driven oncogenic pathways. Supplied as a high-purity solid in small laboratory pack sizes, it is intended for in vitro and preclinical studies; handle per safety data and institutional protocols.
- Selective PI3Kα inhibitor for pathway and cancer research.
- High purity (≈99.6%) suitable for analytical and biological assays.
- Light yellow to yellow solid physical form.
- Available in small research pack sizes, including 10 mg.
- Includes core identifiers: CAS number, formula, and molecular weight.
- Store sealed at 4°C; in solvent, store at -80°C.
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5,564
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000381310 SB-505124 HYDROCHLO 10MM 1ML
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5,565
Medchemexpress LLC Trazodone hydrochloride | 25332-39-2 | 99.6% | 1 ML
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Trazodone hydrochloride is a triazolopyridine derivative that functions as a serotonin receptor antagonist and reuptake inhibitor (SARI). It is recognized for its anti-depressant and anti-insomnious properties, exerting antagonistic effects against α1- and α2-adrenergic receptors and histamine H1 receptors with minimal anticholinergic impact.
- Binds to 5-HT1A receptor with a Ki of 23.6 nM.
- Reduces expression of neuroinflammatory markers.
- Increases mRNA expression of BDNF and CREB.
- Reduces IFN-γ release in neuronal-like cells.
- Increases levels of phosphorylated ERK1/2 and decreases phosphorylated p38 levels.
- Reduces spontaneous motor activity in cats and dogs.
- Inhibits nicotine- and oxotremorine-induced tremor.
- Decreases spontaneous firing rate of DR 5-HT neurons and blocks 5-HT reuptake.
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