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Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.
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Biotin-PEG6-alcohol is a biotin-labeled, PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are compounds that feature two distinct ligands connected by a linker. One ligand targets an E3 ubiquitin ligase and the other targets a specific protein. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is intended for research use only.
Biotin-labeled and PEG-based PROTAC linker
Utilized in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Enables selective degradation of target proteins
Intended for research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Biotin-PEG6-alcohol is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Biotin-labeled: This feature allows for specific targeting or detection in various biological assays due to biotin's high affinity for streptavidin.
PEG-based PROTAC linker: The polyethylene glycol (PEG) chain provides flexibility and enhances solubility, which are advantageous properties for the development of PROTACs (Proteolysis Targeting Chimeras).
Application in PROTAC synthesis: It functions as a key component in the creation of PROTACs.
Mechanism of PROTACs: PROTACs operate by harnessing the intracellular ubiquitin-proteasome system to achieve the selective degradation of target proteins.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More