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Filtered Search Results
Medchemexpress LLC Triethylene glycol monododecyl ether | 3055-94-5 | MFCD00042659 | 100.0% | 318.49 g/mol | C18H38O4 | 250 MG
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Triethylene glycol monododecyl ether is a polyethylene glycol-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs). It provides a flexible, hydrophilic spacer that can improve solubility and help control the distance between binding ligands, supporting linker optimization during medicinal chemistry and chemical biology research.
- Provides a flexible, hydrophilic spacer for bifunctional molecules.
- Improves aqueous solubility of conjugated ligands.
- Enables modulation of inter-ligand distance in PROTAC design.
- Compatible with common organic synthesis transformations.
- Supplied in small-scale quantities suitable for research and development.
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Medchemexpress LLC Triethylene glycol monododecyl ether | 3055-94-5 | MFCD00042659 | 100.0% | 318.49 g/mol | C18H38O4 | 100 MG
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Triethylene glycol monododecyl ether is a monoalkyl PEG ether used as a linker in PROTAC synthesis and related chemical biology applications. It is supplied as a high-purity, research-grade reagent suitable for small-scale synthesis and analytical work.
- Used as a PEG-based linker and amphiphilic spacer in bifunctional molecules.
- High purity for research applications, minimizing impurity-driven side reactions.
- Molecular formula C18H38O4 and molecular weight 318.49 g/mol for precise stoichiometry.
- Liquid form suitable for incorporation into solution-phase syntheses.
- Available in small pack sizes appropriate for medicinal chemistry and method development.
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Medchemexpress LLC Metaldehyde | 108-62-3 | 98.0% | 500 MG
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Metaldehyde is a commonly used pesticide for mollusks such as slugs and snails.
- Purity: 98.0%
- Appearance: Solid
- Color: White to off-white
- Molecular weight: 176.21
- Formula: C8H16O4
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Medchemexpress LLC Bremelanotide acetate (PT-141 acetate) | 1607799-13-2 | 100.0% | 1085.2 g/mol | C52H72N14O12 | 10 MG
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Bremelanotide acetate is a synthetic peptide analogue of α-melanocyte-stimulating hormone that acts as an agonist at melanocortin receptors, primarily MC3R and MC4R. It is supplied as the acetate salt in a lyophilized form for research use, enabling study of melanocortin signaling pathways and sexual function modulation.
- Acts as an agonist at MC3R and MC4R.
- Used to study sexual dysfunction and melanocortin signaling.
- Provided as the acetate salt and lyophilized powder for stability.
- High purity suitable for research applications.
- Available in small research quantities, such as 10 mg.
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TARGETMOL CHEMICALS INC DIETHYL-PYTHIDC 10MG
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Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor. purity: 98%
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Medchemexpress LLC Diethylene glycol | 111-46-6 | 99.9% | 1 KG
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Diethylene glycol (2,2'-Oxybis(ethan-1-ol)) is a biochemical reagent with excellent solubility and reactivity in certain chemical reactions. It can help accelerate the activation of certain reactants and is used as a biological material or organic compound for life science related research.
- Widely used in the production process of pigments, resins, and other chemicals.
- Excellent solubility.
- Excellent reactivity in certain chemical reactions.
- Helps accelerate the activation of certain reactants.
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Medchemexpress LLC Heptaethylene glycol | 5617-32-3 | ≥97.0% | C14H30O8 | 25 G
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Heptaethylene glycol is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs function by connecting two ligands: one targets an E3 ubiquitin ligase, and the other targets a protein of interest. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates targeted protein degradation
- Leverages the ubiquitin-proteasome system
- Suitable for research applications only
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Lifeline Cell Technology Ascorbic Acid LifeFactor - 0.5 mL
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May be used with:FibroLife® basal medium and human fibroblastsVascuLife® basal medium and human smooth muscle cellsVascuLife® basal medium and human endothelial cellsDermaLife basal medium and human melanocytes (neonatal, adult)
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Medchemexpress LLC Monobutyl phthalate-d4 | 478954-81-3 | 10 MG
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Monobutyl phthalate-d4 is a deuterium-labeled form of monobutyl phthalate. Monobutyl phthalate, a key metabolite of dibutyl phthalate (DBP), is recognized for its antiandrogenic effects and as an embryotoxicant. Deuteration, which involves incorporating stable heavy isotopes, is often used for quantitation during drug development and can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be utilized as a tracer.
- Functions as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.
- Features stable heavy isotopes for drug development quantitation.
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Medchemexpress LLC Hexaethylene glycol | 2615-15-8 | 99.5% | 282.33 | 25 MG
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Hexaethylene glycol is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It is intended for research purposes only and not for patient use.
- Used in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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Medchemexpress LLC MCB-613 | 1162656-22-5 | 99.6% | 304.39 | 25 MG
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MCB-613 | 1162656-22-5 | 99.6% | 304.39 | 25 MG
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Medchemexpress LLC Tetraethylene glycol 250mg
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Tetraethylene glycol monohexadecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC Hydroxytyrosol acetate | 69039-02-7 | 100 MG
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Hydroxytyrosol acetate is a prodrug that converts to Hydroxytyrosol in vivo. Hydroxytyrosol, a phenol found in olive oil, alleviates oxidative stress, improves mitochondrial function, and offers neuroprotective effects.
- Induces apoptosis in cancer cells via ROS production
- Shows antibacterial and antiviral effects
- Used in research for cancer, infection, inflammation, immunology, metabolic, neurological, and cardiovascular diseases
- Applications include colon cancer, diabetes, Alzheimer's disease, and atherosclerosis
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Apexbio Technology LLC MCB-613 1162656-22-5 5mg
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MCB-613 (CAS 1162656-22-5) is a small-molecule stimulator of steroid receptor coactivators (SRCs) transcriptional regulators that modulate gene expression downstream of nuclear receptors and signaling pathways It potently activates all three SRC family proteins significantly enhancing their interactions with additional coactivators such as CBP and CARM1 thus amplifying downstream transcriptional activity In cancer models (prostate PC-3 breast MCF-7 liver HepG2 Lung H1299) MCB-613 demonstrates cytotoxicity through selective induction of endoplasmic reticulum stress coupled with reactive oxygen species (ROS) The compound provides a probe for investigating SRC biology and cancer cell dependency on SRC activation
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Medchemexpress LLC Tetraethylene glycol monotosylate | 77544-60-6 | MFCD22056303 | >97.0% | 348.41 g/mol | C15H24O7S | 1 G
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Tetraethylene glycol monotosylate is a tosylated tetraethylene glycol reagent used as a cleavable linker or spacer in bioconjugation and organic synthesis. It is commonly used for antibody-drug conjugate (ADC) linker construction and related medicinal chemistry applications.
- tosylated tetraethylene glycol structure provides a reactive leaving group for conjugation
- cleavable acylhydrazone-compatible spacer for ADC and PROTAC synthesis
- molecular weight 348.41 g/mol and formula C15H24O7S
- CAS number 77544-60-6 for unambiguous identification
- high purity (≥97%) suitable for synthetic applications
- storage in pure form at -20°C or 4°C extends shelf life
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