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Filtered Search Results
Ambeed AMBEED
5000888661 DIAMINODIBENZO-18-CROWN- 250MG
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Aobchem AOBCHEM
5000871965 TERT-BUTYL DIBENZO B D FURAN-2
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Apexbio Technology LLC Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell 10mg
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Nitric Oxide Synthase 599-613 Blocking Peptide Bovine Endothelial Cell is a peptide inhibitor targeting Nitric Oxide Synthase (NOS) It is designed to block NOS activity thereby modulating nitric oxide (NO) synthesis and associated cellular signaling pathways Nitric Oxide Synthase 599-613 Blocking Peptide Bovine Endothelial Cell exerts its biological activity primarily by interfering with the enzymatic function of NOS resulting in reduced NO formation Based on these pharmacological properties Nitric Oxide Synthase 599-613 Blocking Peptide Bovine Endothelial Cell holds research potential in studies of ischemia-reperfusion injury cytokine-mediated inflammation and antihypertensive mechanism evaluation
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eMolecules 2096340-13-3 | 2-Bromo-6-methoxypyridine-4-boronic acid, pinacol ester | Combi-Blocks | MFCD16995251 | 313.990 | C12H17BBrNO3 | 98.000 | COc1cc(cc(Br)n1)B1OC(C)(C)C(C)(C)O1 | 1g | 117545437
2-Bromo-6-methoxypyridine-4-boronic acid, pinacol ester | Combi-Blocks | 2096340-13-3 | MFCD16995251 | 313.990 | C12H17BBrNO3 | 98.000 | COc1cc(cc(Br)n1)B1OC(C)(C)C(C)(C)O1 | 1g | 117545437
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Apexbio Technology LLC CPI-613 95809-78-2 10mg
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CPI-613 (CAS 95809-78-2) is an anticancer small molecule targeting mitochondrial energy metabolism It acts by inhibiting the pyruvate dehydrogenase (PDH) complex and -ketoglutarate dehydrogenase ( -KGDH) enzyme complexes involved in mitochondrial carbon metabolism that rely on lipoate cofactors CPI-613 a lipoate derivative disrupts mitochondrial bioenergetics decreasing ATP levels and mitochondrial membrane potential in cancer cells In vitro CPI-613 suppresses proliferation and induces apoptosis in acute myeloid leukemia (AML) cell lines such as HL60 Jurkat and K562 (IC50 16 4 M 13 4 M 12 2 M respectively) In vivo studies demonstrate tumor growth inhibition in mouse xenograft models of human non-small cell lung carcinoma (H460) and pancreatic tumor (BxPC-3) highlighting its research potential in oncology
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eMolecules 17455-13-9 | 18-CROWN-6 | AstaTech | MFCD00005113 | 264.318 | C12H24O6 | 97.000 | C1COCCOCCOCCOCCOCCO1 | 100g | 206677497
18-CROWN-6 | AstaTech | 17455-13-9 | MFCD00005113 | 264.318 | C12H24O6 | 97.000 | C1COCCOCCOCCOCCOCCO1 | 100g | 206677497
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![eMolecules 1256360-22-1 | 5-Methoxyindole--2,7-diboronic acid, pinacol ester | Combi-Blocks | MFCD15474883 | 399.100 | C21H31B2NO5 | 96.000 | COc1cc(B2OC(C)(C)C(C)(C)O2)c2[nH]c(cc2c1)B1OC(C)(C)C(C)(C)O1 | 1g | 117545995](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502191993.JPG-250.jpg)
eMolecules 1256360-22-1 | 5-Methoxyindole--2,7-diboronic acid, pinacol ester | Combi-Blocks | MFCD15474883 | 399.100 | C21H31B2NO5 | 96.000 | COc1cc(B2OC(C)(C)C(C)(C)O2)c2[nH]c(cc2c1)B1OC(C)(C)C(C)(C)O1 | 1g | 117545995
5-Methoxyindole--2,7-diboronic acid, pinacol ester | Combi-Blocks | 1256360-22-1 | MFCD15474883 | 399.100 | C21H31B2NO5 | 96.000 | COc1cc(B2OC(C)(C)C(C)(C)O2)c2[nH]c(cc2c1)B1OC(C)(C)C(C)(C)O1 | 1g | 117545995
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Frontier Specialty Chemicals 25G 2-METHOXYPYRIMIDINE-5-BORO
2-Methoxypyrimidine-5-boronic acid
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Ambeed 2Bromo5methoxypyridine
2-Bromo-5-methoxypyridine, 105170-27-2, 98%
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eMolecules 71050-40-3 | 4-Methoxythiophene-3-carboxylic acid | Combi-Blocks, Inc. | MFCD00067997 | 158.170 | C6H6O3S | 96.000 | COc1cscc1C(O)=O | 25g | 603136087
4-Methoxythiophene-3-carboxylic acid | Combi-Blocks, Inc. | 71050-40-3 | MFCD00067997 | 158.170 | C6H6O3S | 96.000 | COc1cscc1C(O)=O | 25g | 603136087
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Apexbio Technology LLC MCB-613 1162656-22-5 5mg
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MCB-613 (CAS 1162656-22-5) is a small-molecule stimulator of steroid receptor coactivators (SRCs) transcriptional regulators that modulate gene expression downstream of nuclear receptors and signaling pathways It potently activates all three SRC family proteins significantly enhancing their interactions with additional coactivators such as CBP and CARM1 thus amplifying downstream transcriptional activity In cancer models (prostate PC-3 breast MCF-7 liver HepG2 Lung H1299) MCB-613 demonstrates cytotoxicity through selective induction of endoplasmic reticulum stress coupled with reactive oxygen species (ROS) The compound provides a probe for investigating SRC biology and cancer cell dependency on SRC activation
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![eMolecules 13745-42-1 | N-Phenyl-1H-1,3-benzodiazole-2-carboxamide | Oakwood Chemical237.262 | C14H11N3O | 98.000 | O=C(Nc1ccccc1)c1nc2ccccc2[nH]1 | 250mg | 596366730](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502150440.JPG-250.jpg)
eMolecules 13745-42-1 | N-Phenyl-1H-1,3-benzodiazole-2-carboxamide | Oakwood Chemical237.262 | C14H11N3O | 98.000 | O=C(Nc1ccccc1)c1nc2ccccc2[nH]1 | 250mg | 596366730
N-Phenyl-1H-1,3-benzodiazole-2-carboxamide | Oakwood Chemical | 13745-42-1237.262 | C14H11N3O | 98.000 | O=C(Nc1ccccc1)c1nc2ccccc2[nH]1 | 250mg | 596366730
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eMolecules 1150632-93-1 | 2-(Dimethoxymethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | MFCD16038216 | 1g
Medchem Express | TC-N 1752 | 5mg | 721611029 | HY-107405 | 1211866-85-1 | MFCD22123242 | 516.525 | C25H27F3N6O3
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eMolecules 1313738-12-3 | (3-FLUORO-4-(METHOXYMETHYL)PHENYL)BORONIC ACID | MFCD14687259 | 0.25g
Ambeed | NN-Diethyl-1-(methylsulfonyl)methanamide | 100mg | 714082867 | A1446467 | 155514-79-7 | MFCD00870026 | 179.230 | C6H13NO3S
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
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5000338518 A-MSH 11-13 ACETA 50MG
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