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Organic disulfides

Organosulfur compounds that contain a disulfide functional group; disulfide groups consist of two bonded sulfur atoms (S-S). Disulfide groups are also called disulfide bridge or SS-bond.

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Medchemexpress LLC (R)-NX-2127 | 3024312-52-2 | 98.9% | 719.83 | C39H45N9O5 | 10 MG
SDP

(R)-NX-2127 is the R-isomer of a Bruton's tyrosine kinase (BTK) PROTAC degrader supplied as a high-purity solid for preclinical research. The compound is intended for use in studies of BTK degradation and related cellular pharmacology; consult the supplier product page and SDS for handling and storage details.

  • R-isomer of a BTK PROTAC degrader
  • High reported purity (98.93%)
  • Molecular weight 719.83
  • Chemical formula C39H45N9O5
  • Solid, light yellow to yellow appearance
  • Recommended storage: 4°C protected from light; in solvent -80°C (6 months) or -20°C (1 month)
  • Intended for preclinical BTK degradation and cellular assays

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2

TARGETMOL CHEMICALS INC NX-2127 1MG
SDP

Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 cells.NX-2127 potently catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) at 25 nM and 54 nM, respectively. NX-2127 is associated with the immune system, stimulating T cell activation and increasing IL-2 production in primary human T cells. Purity 98.11%

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