Sulfoxides
eMolecules 67-68-5 | Dimethyl Sulfoxide | AA Blocks LLC | MFCD00002089 | 78.130 | C2H6OS | 0.000 | CS(C)=O | 250g | 784389378
Dimethyl Sulfoxide | AA Blocks LLC | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 0.000 | CS(C)=O | 250g | 784389378
Medchemexpress LLC Cytochrome P450 2E1 Antibody (YA2302) | 50 UL
Cytochrome P450 2E1 Antibody (YA2302) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting Cytochrome P450 2E1. It is for research use only and demonstrates endogenous sensitivity. This antibody is supplied as a liquid formulation in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide, and 50% glycerol.
- Involved in fatty acid metabolism and potentially xenobiotic oxidative metabolism.
- Catalyzes hydroxylation of carbon-hydrogen bonds, specifically at the omega-1 position of saturated fatty acids.
- Subcellular localization includes endoplasmic reticulum membrane, microsome membrane, and mitochondrion inner membrane.
- Application in western blot (WB) with a dilution ratio of 1:500-1:1000.
- Species reactivity includes human, mouse, and rat.
- Immunogen is a synthesized peptide derived from human CYP2E1 aa52-114.
Medchemexpress LLC Sulindac sulfide | 49627-27-2 | MFCD00078044 | 98.1% | 1 ML
Sulindac sulfide is a noncompetitive γ-secretase inhibitor, demonstrating an IC50 of 20.2 μM for γ42-secretase activity. This compound is primarily utilized in neurological disease research, targeting drug metabolites and γ-secretase.
- Noncompetitive γ-secretase inhibitor
- IC50 of 20.2 μM for γ42-secretase activity
- Targeted for drug metabolite research
- Used in neurological disease studies
Medchemexpress LLC CB2 modulator 1 | 666261-80-9 | 99.8% | 380.36 | C18H19F3N4O2 | 5 MG
CB2 modulator 1 is a potent small-molecule modulator of the cannabinoid receptor CB2 intended for research use. It has reported activity relevant to immune disorders, inflammation, osteoporosis, and renal ischemia. Supplied as a high-purity solid for in vitro and exploratory studies; follow appropriate safety and regulatory guidance.
- Acts on cannabinoid receptor CB2.
- Reported activity in immune disorders, inflammation, osteoporosis, and renal ischemia.
- CAS number 666261-80-9.
- Molecular formula C18H19F3N4O2.
- Molecular weight 380.36 g/mol.
- Purity 99.75% (reported).
- Available in small pack sizes for screening, e.g., 5 mg.
- Intended for research use only; follow appropriate safety guidance.
Sigma Aldrich Fine Chemicals Biosciences Methyl sulfoxide >=99%, FG | 67-68-5 | MFCD00002089 | 1KG
Methyl sulfoxide >=99%, FG | Purity: >=99% | Mol Wt: 78.13 | 67-68-5 | MFCD00002089 | 1KG
AdipoGen Prosulfocarb sulfoxide
Chemical. CAS 51954-81-5. Formula C14H21NO2S. MW 267.39. Metabolite of the herbicide Prosulfocarb. Can be used as a reference compound.
Apexbio Technology LLC Sulindac 38194-50-2 100mg
Sulindac (CAS 38194-50-2) is a nonsteroidal anti-inflammatory drug that functions as a prodrug and is metabolized in vivo to pharmacologically active sulindac sulfide and sulindac sulfone Sulindac sulfide acts as a cyclooxygenase inhibitor and modulates intracellular signaling pathways including the repression of ras activity Sulindac sulfone possesses antitumor properties independent of cyclooxygenase inhibition Due to these distinct metabolites and their activities sulindac is utilized in biomedical research for studying inflammatory processes cyclooxygenase-mediated pathways and the chemopreventive mechanisms involved in tumorigenesis
Medchemexpress LLC Tnfa Activ Modulator 3 Reconst | HY-160412-1MM/1ML RECONST
Tnfa Activ Modulator 3 Reconst
Medchemexpress LLC Smurf1 modulator-1 | 1825371-51-4 | 99.8% | 446.54 | 5 MG
Smurf1 modulator-1 (Compound 20) is a selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1), with IC50 of 180 nM.
- Selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1) with an IC50 of 180 nM.
- For research use only.
Medchemexpress LLC Mrgprx4 modulator-1 | 2492596-61-7 | 98.1% | C16H13ClF3NO3 | 10MG
MRGPRX4 modulator-1 is a small-molecule modulator of the Mas-related G-protein coupled receptor X4 used as a research tool for in vitro pharmacology and receptor signaling studies. It is supplied as a solid and as ready-to-use DMSO solutions, and is characterized by defined chemical identity, high purity, and documented storage recommendations.
- Modulates MRGPRX4 receptor activity in vitro.
- Available as solid and DMSO solution formats for flexible use.
- High purity suitable for research applications.
- Documented chemical identity (CAS 2492596-61-7) and formula C16H13ClF3NO3.
- Stable when stored under recommended conditions for extended shelf life.
Medchemexpress LLC A1AT modulator 1 | 2406205-61-4 | 99.8% | 370.42 | C21H23FN2O3 | 5 MG
A1AT modulator 1 is a research-grade small molecule inhibitor used to study Z α1-antitrypsin polymerization and related biochemical pathways. The compound is a solid (white to off-white) with molecular formula C21H23FN2O3 and molecular weight 370.42. It is provided for laboratory research use with storage recommendations for both powder and solution to maintain stability.
- Potent inhibitor of Z α1-antitrypsin polymerization (pIC50 = 8.3).
- High analytical purity (99.77%).
- Solid, white to off-white appearance suitable for handling in lab settings.
- Stable when stored under recommended conditions (powder: -20°C or 4°C; in solvent: -80°C or -20°C).
- Provided in small-quantity packaging appropriate for research assays.
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 1 ML
CB2R/FAAH modulator-3 is a dual-targeting modulator that functions as a Cannabinoid receptor 2 (CB2R) agonist and a Fatty Acid Amide Hydrolase (FAAH) inhibitor. This modulator demonstrates a high affinity for CB2R with a Ki value of 20.1 nM, and a lower affinity for CB1R with a Ki value of 67.6 nM. It inhibits FAAH with an IC50 value of 3.4 μM. In in vitro studies, at a concentration of 10 μM, it has been shown to reduce the production of pro-inflammatory cytokines, including TNFα, IFN-γ, IL-1β, and IL6, in unstimulated monocytes and macrophages.
- Suitable for use in research related to various conditions, such as cancer.
- Suitable for use in research related to inflammatory cascades associated with neurodegenerative diseases.
- Suitable for use in research related to COVID-19 infection.