Sulfoxides
Cayman Chemical SulIndac sulfon 25mg
An oxidized metabolite of sulindac that is produced in many mammals but minimally in mice and rats; generally considered to be inactive against COX enzymes, although it can reduce azoxymethane-induced colon cancer in rats; inhibits aldose reductase (IC50 = 367 nM) in vitro
TARGETMOL CHEMICALS INC GPR40/FFAR1 MODULATOR 1 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator. purity: 99%
Medchemexpress LLC Iduronate 2-sulfatase | 50936-59-9 | >95.0% | 500 UG
Recombinant human iduronate 2-sulfatase (IDS) is a lysosomal enzyme produced in HEK293 cells and supplied lyophilized as an active, His-tagged protein for biochemical and enzymatic studies. It hydrolyzes the C2-sulfate ester of glycosaminoglycans and is provided with validated purity and activity specifications.
- Expressed in HEK293 cells.
- C-terminal 10xHis tag for purification.
- Purity >95.0% by reducing SDS-PAGE.
- Specific activity 6.123 pmoL/min/μg (PNCS substrate assay).
- Lyophilized from 0.22 μm filtered PBS, pH 7.4.
- Approximate molecular weight 75-95 kDa due to glycosylation.
- Store at -20°C; after reconstitution stable at 4°C for 1 week.
- Available in a 500 μg size.
Medchemexpress LLC Iduronate 2-sulfatase, recombinant human (His-tag) | 50936-59-9 | >95.0% | 5 UG
Recombinant human iduronate 2-sulfatase (IDS) produced in HEK293 cells and provided as a lyophilized, C-terminal His-tagged protein for research applications. The glycosylated enzyme is highly pure and supplied with low endotoxin; enzymatic activity is reported by manufacturer assay. Follow storage and reconstitution instructions for optimal stability.
- Expressed in HEK293 cells
- C-terminal His tag for purification and detection
- Purity >95.0% by reducing SDS-PAGE
- Endotoxin <1 EU/μg
- Specific activity ~6.1 pmoL/min/μg
- Lyophilized formulation; reconstitute per instructions
- Store frozen; aliquot to avoid freeze-thaw
Medchemexpress LLC NR2F6 modulator-1 | 904449-84-9 | 99.5% | 419.45 | 100 MG
NR2F6 modulator-1 is a potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator. It can be used for researching immune modulation and modulation of cancer stem cell activity.
- Potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator.
- Useful for researching immune modulation.
- Useful for researching modulation of cancer stem cell activity.
![Medchemexpress LLC 2-Quinoxalinecarboxamide, N-[2-[3-[(4-amino-1-piperidinyl)methyl]imidazo[2,1-b]thiazol-6-yl]phenyl]- | 925437-38-3 | 96.2% | 483.59 | 500 UG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385638-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Quinoxalinecarboxamide, N-[2-[3-[(4-amino-1-piperidinyl)methyl]imidazo[2,1-b]thiazol-6-yl]phenyl]- | 925437-38-3 | 96.2% | 483.59 | 500 UG
Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. It significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). This modulator regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases and inflammatory diseases. It also causes a significant decrease in MCP-1 expression in a human leukocyte (WBC) model, indicating its potential to inhibit inflammatory responses.
- Activates sirtuin activity.
- Downregulates MCP-1 expression.
- Upregulates FGF21 expression.
- Shows potential for studying metabolic diseases.
- Shows potential for studying inflammatory diseases.
Medchemexpress LLC Bithionol (sulfoxide) | 844-26-8 | 99.0% | 372.05 | 100 MG
Bithionol sulfoxide is an anti-infection agent specifically used for parasites. It exhibits mutagenic activity. This compound is utilized in research concerning parasitic infections such as paragonimiasis, flukes, and cestodes infection.
- Functions as an anti-infection agent targeting parasites.
- Observed to possess mutagenic activity.
- Suitable for research applications related to parasitic infections.
- Can be used for research into parasitic infections including paragonimiasis, flukes, and cestodes infection.
