Sulfoxides
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 25 MG
CB2R/FAAH modulator-3 is a dual-targeting modulator that acts as a CB2R agonist and FAAH inhibitor. It has potential applications in studies related to cancer, neurodegenerative diseases, and COVID-19 infection.
- Acts as a dual-targeting modulator
- Functions as a CB2R agonist and FAAH inhibitor
- Exhibits Ki values of 20.1 nM for CB2R and 67.6 nM for CB1R
- Has an IC50 value of 3.4 μM for FAAH
- Reduces pro-inflammatory cytokines such as TNFα, IFN-γ, IL-1β, and IL6 in unstimulated monocytes and macrophages at 10 μM
Medchemexpress LLC NR2F6 modulator-1 | 904449-84-9 | 99.5% | 419.45 | 100 MG
NR2F6 modulator-1 is a potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator. It can be used for researching immune modulation and modulation of cancer stem cell activity.
- Potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator.
- Useful for researching immune modulation.
- Useful for researching modulation of cancer stem cell activity.
Medchemexpress LLC A1AT modulator 1 | 2406205-61-4 | 99.8% | 370.42 | C21H23FN2O3 | 5 MG
A1AT modulator 1 is a research-grade small molecule inhibitor used to study Z α1-antitrypsin polymerization and related biochemical pathways. The compound is a solid (white to off-white) with molecular formula C21H23FN2O3 and molecular weight 370.42. It is provided for laboratory research use with storage recommendations for both powder and solution to maintain stability.
- Potent inhibitor of Z α1-antitrypsin polymerization (pIC50 = 8.3).
- High analytical purity (99.77%).
- Solid, white to off-white appearance suitable for handling in lab settings.
- Stable when stored under recommended conditions (powder: -20°C or 4°C; in solvent: -80°C or -20°C).
- Provided in small-quantity packaging appropriate for research assays.
Medchemexpress LLC Sirtuin modulator 2 | 667910-69-2 | 99.2% | 349.41 | 25 MG
Sirtuin modulator 2 (Compound 132) is a sirtuin modulator exhibiting an ED50 equal to or less than 50 μM. It is intended for research use only. This compound is characterized by its molecular weight of 349.41 and appears as a light yellow to yellow solid.
- Appears as a light yellow to yellow solid.
- Has an ED50 equal to or less than 50 μM.
- Intended for research applications.
Medchemexpress LLC (R)-Sulforaphane | 142825-10-3 | 99.95% | 177.29 | 5 MG
(R)-Sulforaphane is an orally active and potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. It primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. This compound modulates gene expression, influencing various signaling pathways, including Nrf2, NF-κB, and AP-1.
- Can be used in studies of tumor biology, antioxidant defense mechanisms, inflammation, and immune responses
- Promotes transcription of tumor-suppressing proteins
- Effectively inhibits HDAC activity
- Offers cardiac protection by activating the Keap1/Nrf2/ARE pathway and inducing HO-1 expression
- Suppresses high glucose-induced pancreatic cancer via AMPK-dependent signal transmission
- Storage at -20°C, protect from light, stored under nitrogen
- Unstable in solutions, freshly prepared is recommended
Medchemexpress LLC Cytochrome P450 24A1 Antibody (YA2121) | 50 UL
Cytochrome P450 24A1 Antibody (YA2121) is a rabbit-derived, non-conjugated IgG monoclonal antibody specifically targeting Cytochrome P450 24A1. This antibody is intended for research use only. Cytochrome P450 24A1 is a monooxygenase crucial for vitamin D catabolism and calcium homeostasis, inactivating calcidiol and calcitriol via C24- and C23-oxidation pathways.
- Host: Rabbit
- Clonality: Monoclonal
- Conjugation: Non-conjugated
- Isotype: IgG
- Appearance: Liquid
- Purity: Affinity chromatography
- Application: Western blot (WB)
- Dilution ratio: 1:500-1:1000
- Species reactivity: Human
- Molecular weight: 59 kDa (predicted and observed)
- Subcellular localization: Mitochondrion
- Research field: Cardiovascular
Medchemexpress LLC KAT modulator-1 | 1314006-43-3 | C20H36O2 | 50 MG
KAT modulator-1 is a laboratory chemical identified for research use only. It has a molecular formula of C20H36O2 and a molecular weight of 308.50. This substance appears as a solid and is considered stable under recommended storage conditions, though it has not been fully validated for medical applications.
- Not classified as a hazardous substance
- Stable under recommended storage conditions
- Store in a tightly sealed container in a cool, well-ventilated area
- Avoid direct sunlight and ignition sources
- Recommended powder storage: -20°C for 3 years, 4°C for 2 years
- Recommended in-solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Sulforaphane | 4478-93-7 | MFCD00198068 | 98.9% | 177.29 g/mol | C6H11NOS2 | 5 MG
Sulforaphane is a research-grade isothiocyanate that activates the Keap1/Nrf2/ARE antioxidant pathway and inhibits histone deacetylases. Supplied as a high-purity powder, it is intended for use in in vitro and in vivo studies of antioxidant response, anticancer activity, and anti-inflammatory mechanisms.
- High purity: 98.9%.
- CAS number: 4478-93-7.
- Molecular formula: C6H11NOS2; MW: 177.29 g/mol.
- Suitable for in vitro and in vivo applications.
- Storage: powder -20°C; in solvent -80°C for long-term storage.
- Available in small research quantities, including 5 mg.
