Sulfoxides
Medchemexpress LLC (+)-LRH-1 modulator-1 | 00-00-0 | 99.4% | C28H36N2O2S | 10MG
(+)-LRH-1 modulator-1 is the (+)-stereoisomer of an LRH-1 modulator and functions as a potent agonist of liver receptor homolog-1 (LRH-1). It modulates inflammatory signaling in intestinal organoid models by inducing IL-10 and reducing IL-1β and TNFα. The compound is provided as a high-purity research-grade small molecule for cellular and biochemical studies of LRH-1 pathways.
- Potent LRH-1 modulator/agonist for receptor pharmacology studies.
- Induces anti-inflammatory cytokine IL-10 in organoid models.
- Reduces proinflammatory cytokines IL-1β and TNFα in assays.
- High purity suitable for cellular and biochemical experiments.
- Available in multiple small-scale quantities for research use.
Medchemexpress LLC Sulindac-d3 | 99.4% | C20H14D3FO3S | 5 MG
Sulindac-d3 is a deuterium labeled non-steroidal anti-inflammatory agent that acts as a COX-2 inhibitor, inhibiting its overexpression. It is supplied as a light yellow to yellow solid.
- Deuterium labeled Sulindac
- Non-steroidal anti-inflammatory agent
- Acts as a COX-2 inhibitor
- Purity: 99.4% (HPLC)
- Isotopic enrichment: 99.8%
- Storage (powder): -20°C for 3 years
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC mGluR3 modulator-1 | 374548-18-2 | MFCD01957075 | 98.7% | 271.36 g·mol⁻1 | C16H21N3O | 10 MG
mGluR3 modulator-1 is a small-molecule modulator of the metabotropic glutamate receptor 3 (mGluR3) intended for research use. It demonstrates activity in cellular calcium mobilization assays (EC50 = 1-10 μM) and is supplied with a reported high purity and defined molecular properties suitable for in vitro pharmacology and receptor profiling studies.
- Modulates mGluR3 receptor activity in cell-based assays.
- Demonstrated EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 calcium mobilization assay.
- High purity suitable for research applications.
- Available in small mass packages for screening and assay work.
- Includes chemical identifiers for traceability, such as CAS 374548-18-2.
Medchemexpress LLC Cytochrome P450 27A1 antibody (YA2163) | 100 UL
Cytochrome P450 27A1 Antibody (YA2163) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Cytochrome P450 27A1. This enzyme plays a crucial role in cholesterol homeostasis by catalyzing the hydroxylation of cholesterol and its derivatives, leading to bile acid synthesis and modulation of lipid metabolism genes.
- Rabbit-derived monoclonal antibody
- Targets Cytochrome P450 27A1
- Non-conjugated IgG
- Reactive with human, mouse, and rat samples
- Purified by affinity chromatography
- Predicted band size: 60 kDa; Observed band size: 50 kDa
- Suitable for WB, IHC-P, ICC/IF, and FC applications
