Sulfoxides
Medchemexpress LLC Hydrazinecarbothioamide, 2-(1H-indol-3-ylmethylene)-N-(4-methylphenyl)-, (2E)- | 2097787-75-0 | 99.0% | 308.40 | 50 MG
Nur77 modulator 3 is a chemical compound that acts as a modulator of the Nur77 receptor. Modulators are typically used in research to study receptor function and signaling pathways. This product is suitable for laboratory research and development applications.
- A chemical compound
- Used for receptor study
- Suitable for research applications
Medchemexpress LLC Sodium decane-1-sulfonate | 13419-61-9 | 244.33 | 1 G
Sodium decane-1-sulfonate is an anionic surfactant primarily used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography. It appears as a solid and is intended for research use only.
- Anionic surfactant
- Used for analysis of organic small molecule compounds
- Applicable in HPLC and ion-pair liquid chromatography
- Solid appearance
- For research use only
Medchemexpress LLC Kv3.1 modulator 2 | 99.8% | 437.88 | 50 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This modulator is suitable for laboratory research and studies involving Kv3.1 channels.
- Functions as a Kv3.1 channels modulator
- Has an EC50 value of 68 nM
Medchemexpress LLC Benzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl- | 1050506-87-0 | 97.1% | C20H18ClNO3S | 1 ML
GPR120 modulator 2 is a chemical compound with a molecular formula of C20H18ClNO3S and a molecular weight of 387.88. This compound is a white to off-white solid and has a purity of 97.11% as determined by HPLC, with its mass spectrometry consistent with its structure.
- Molecular formula: C20H18ClNO3S
- Molecular weight: 387.88
- Appearance: White to off-white solid
- Purity (HPLC): 97.11%
- Mass spectrometry consistent with structure
Medchemexpress LLC GPR120 modulator 1 | 1050506-75-6 | 98.06% | C19H16ClNO4S | 50 MG
GPR120 modulator 1 is a G protein-coupled receptor 120 (GPR120) modulator, extracted from patent US8394841B2, compound example F1. It is intended for research use only and can be used for the study of diseases associated with abnormal or deregulated GPR120, such as diabetes.
- G protein-coupled receptor 120 (GPR120) modulator
- Extracted from patent US8394841B2, compound example F1
- Useful for research of diseases associated with abnormal or deregulated GPR120, such as diabetes
- For research use only
Medchemexpress LLC GLP-1R modulator L7-028 | 2648317-95-5 | MFCD34602898 | 99.5% | 392.49 | C24H28N2O3 | 5 MG
GLP-1R modulator L7-028 is a small-molecule positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R). It enhances GLP-1 binding at a transmembrane site (reported EC50 11.01 ± 2.73 μM) and is supplied for research use only as a solid with high analytical purity for in vitro studies of GLP-1R signaling.
- Enhances GLP-1 binding via a transmembrane allosteric site.
- Reported EC50 11.01 ± 2.73 μM for GLP-1R modulation.
- High analytical purity suitable for research (≈99.5%).
- Available in small pack sizes for laboratory use.
- Molecular formula C24H28N2O3 and molecular weight 392.49.
Apexbio Technology LLC Sulindac 38194-50-2 10mM (in 1mL DMSO)
Sulindac (CAS 38194-50-2) is a nonsteroidal anti-inflammatory drug that functions as a prodrug and is metabolized in vivo to pharmacologically active sulindac sulfide and sulindac sulfone Sulindac sulfide acts as a cyclooxygenase inhibitor and modulates intracellular signaling pathways including the repression of ras activity Sulindac sulfone possesses antitumor properties independent of cyclooxygenase inhibition Due to these distinct metabolites and their activities sulindac is utilized in biomedical research for studying inflammatory processes cyclooxygenase-mediated pathways and the chemopreventive mechanisms involved in tumorigenesis
Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | >99.0% | C27H34N6O2 | 1 MG
IL-17 modulator 4 is a proagent of IL-17 modulator 1, an orally active and highly efficacious IL-17 modulator. This compound is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome. It modulates IL-17A protein-protein interaction by stabilizing the conformation of the IL-17A dimer, preventing binding to the IL-17RA receptor and inhibiting the IL-17A-mediated signaling pathway. It demonstrates favorable pharmacokinetic properties with excellent oral bioavailability.
- Modulates IL-17A protein-protein interaction
- Stabilizes IL-17A dimer conformation
- Inhibits IL-17A-mediated signaling pathway
- Potential for research in inflammation and autoimmune diseases
- Exhibits good pharmacokinetic properties in rat models
- Offers high oral bioavailability
Medchemexpress LLC Sirtuin modulator 3 25mg | 25mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
Medchemexpress LLC IL-17 modulator 3 | 2467731-88-8 | 99.51% | 579.73 | 1 ML
IL-17 modulator 3 is an IL-17 modulator that can be used for the research of inflammation, cancer, and autoimmune diseases. This product is for research use only and not sold to patients.
- Used for research of inflammation
- Used for research of cancer
- Used for research of autoimmune diseases
Medchemexpress LLC (+)-LRH-1 modulator-1 | 00-00-0 | 99.4% | C28H36N2O2S | 10MG
(+)-LRH-1 modulator-1 is the (+)-stereoisomer of an LRH-1 modulator and functions as a potent agonist of liver receptor homolog-1 (LRH-1). It modulates inflammatory signaling in intestinal organoid models by inducing IL-10 and reducing IL-1β and TNFα. The compound is provided as a high-purity research-grade small molecule for cellular and biochemical studies of LRH-1 pathways.
- Potent LRH-1 modulator/agonist for receptor pharmacology studies.
- Induces anti-inflammatory cytokine IL-10 in organoid models.
- Reduces proinflammatory cytokines IL-1β and TNFα in assays.
- High purity suitable for cellular and biochemical experiments.
- Available in multiple small-scale quantities for research use.