Sulfoxides
Medchemexpress LLC Kv3 modulator 2 | 2101321-76-8 | 99.9% | 379.41 g·mol⁻¹ | C21H21N3O4 | 5 MG
Kv3 modulator 2 is a small-molecule modulator of Kv3 voltage-gated potassium channels with reported analgesic activity. It is provided for laboratory research use and is characterized by a defined molecular formula and molecular weight, and high purity suitable for preclinical studies.
- High purity (99.9%).
- Available in small research quantities (example: 5 mg).
- Molecular formula C21H21N3O4; molecular weight 379.41 g·mol⁻¹.
- Reported Kv3 channel modulatory activity with analgesic effects.
- For research use only; not for human or clinical use.
FOCUS BIOMOLECULES Biochemical Reagents, UHMCP1, Spliceosome modulator, CAS Unknown, 97% by HPLC/NMR (Conforms)
Biochemical Reagents, UHMCP1, Spliceosome modulator, CAS Unknown, 97% by HPLC/NMR (Conforms), UHMCP1 prevents the interaction (KD 80 uM) between the splicing factor SF3b155 and U2AF homology motif domain (UHM) U2AF65.1 The spliceosomal gene SF3B1 (which encodes for SF3b155) is frequently mutated in cancers as is the splicing factor U2AF.2 UHMCP1 displaying toxicity against HEK293 cells (EC50 140 uM) and various effects on pre-mRNA accumulation or intron retention, exon skipping and inclusion.1 An interesting new tool for study of the spliceosome.
![Medchemexpress LLC 4-Thiazolecarboxamide, 5-(3-methoxypropyl)-2-phenyl-N-[2-[6-(1-pyrrolidinylmethyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]-,hydrochloride | 2070015-26-6 | 99.85% | 606.20 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403398-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 4-Thiazolecarboxamide, 5-(3-methoxypropyl)-2-phenyl-N-[2-[6-(1-pyrrolidinylmethyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]-,hydrochloride | 2070015-26-6 | 99.85% | 606.20 | 25 MG
Sirtuin modulator 1 is a modulator of SIRTl, a homolog of SIRT3, with EC1.5 of < 1 μM. It was extracted from patent WO 2010071853 A1, Compound No.4.
- Modulates SIRTl, a homolog of SIRT3.
- Has an EC1.5 of less than 1 μM.
- Extracted from patent WO 2010071853 A1.
- Identified as Compound No.4 in the patent.
Cell Signaling Technology Mitochondrial Fusion Promoter M1 25 mg
Mitochondrial Fusion Promoter M1 25 mg
Medchemexpress LLC Kv3.1 modulator 2 | 3035827-42-7 | 99.8% | 437.88 | 5 MG
Kv3.1 modulator 2 (compound 4) is a Kv3.1 channels modulator with an EC50 value of 68 nM. This product is for research use only and is not sold to patients.
- Kv3.1 channels modulator
- EC50 value of 68 nM
Medchemexpress LLC Sirtuin modulator 1 | 2070015-26-6 | 99.85% | 606.20 | 100 MG
Sirtuin modulator 1 is a compound that acts as a modulator of SIRTl, a homolog of SIRT3. This compound has an EC1.5 of less than 1 μM and was extracted from patent WO 2010071853 A1, Compound No.4.
- Modulator of SIRTl, a homolog of SIRT3
- High purity of 99.85%
- Solid appearance, light yellow to yellow color
- Molecular weight of 606.20
- Soluble in DMSO at 12.5 mg/mL