Sulfoxides
Medchemexpress LLC GLP-1R modulator C5 | 421578-93-0 | 99.81% | C24H21NO3 | 50 MG
GLP-1R modulator C5 is an allosteric modulator that enhances GLP-1 binding to GLP-1R through a transmembrane site, with an EC50 of 1.59 ± 0.53 μM. It is intended for research use only.
- Allosteric modulator
- Enhances GLP-1 binding to GLP-1R
- Intended for research use only
Medchemexpress LLC IL-17 modulator 3 | 2467731-88-8 | >99.5% | 579.73 | 100 MG
IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases.
- Functions as an IL-17 modulator
- Supports research in inflammation
- Aids studies related to cancer
- Useful in autoimmune disease research
Medchemexpress LLC IL-17 modulator 3 | 2467731-88-8 | 99.51% | 579.73 | 1 ML
IL-17 modulator 3 is an IL-17 modulator that can be used for the research of inflammation, cancer, and autoimmune diseases. This product is for research use only and not sold to patients.
- Used for research of inflammation
- Used for research of cancer
- Used for research of autoimmune diseases
Medchemexpress LLC Mutant p53 modulator-1 | 2746371-35-5 | 99.89% | C27H32F4N8O2 | 25 MG
Mutant p53 modulator-1 is a compound that acts as a mutant p53 modulator. It reduces the progression of cancers containing a p53 mutation. This product is for research use only and not intended for patient use.
- Reduces progression of cancers with p53 mutation
- For research use only
- Powder storage at -20°C for 3 years, or 4°C for 2 years
- In solvent storage at -80°C for 6 months, or -20°C for 1 month
- Appears as a light yellow to brown solid
- Purity of 99.89% by HPLC
Apexbio Technology LLC Sulforaphane(Synonyms: Broccoli sulforaphane, DL-Sulforaphane, R-Sulforaphane, 1-Isothiocyanato-4-(methylsulfinyl)butane), 25mg, CAS: 4478-93-7.
Sulforaphane (CAS 4478-93-7) is a naturally occurring isothiocyanate abundantly found in vegetables especially broccoli It acts primarily through activation of the Keap1-Nrf2 signaling pathway enhancing cellular defense against oxidative and electrophilic stress Sulforaphane has demonstrated antiproliferative activity in vitro as shown by dose-dependent cell cycle arrest at G2/M and apoptosis induction in HT29 human colon carcinoma cells Such effects involve elevated cyclin A and B1 levels increased pro-apoptotic Bax expression mitochondrial cytochrome c release and poly(ADP-ribose) polymerase cleavage These properties make sulforaphane relevant for investigating cancer chemoprevention and cellular stress responses
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 100 MG
GLP-1R modulator C16 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site with an EC50 of 8.43 ± 3.82 μM. It has a molecular weight of 408.89, appears as a solid with a white to off-white color, and is for research use only.
- Enhances GLP-1 binding to GLP-1R
- Allosteric modulator
- Molecular weight of 408.89
- Appears as a solid
- White to off-white color
- For research use only
Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | >99.0% | C27H34N6O2 | 1 MG
IL-17 modulator 4 is a proagent of IL-17 modulator 1, an orally active and highly efficacious IL-17 modulator. This compound is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome. It modulates IL-17A protein-protein interaction by stabilizing the conformation of the IL-17A dimer, preventing binding to the IL-17RA receptor and inhibiting the IL-17A-mediated signaling pathway. It demonstrates favorable pharmacokinetic properties with excellent oral bioavailability.
- Modulates IL-17A protein-protein interaction
- Stabilizes IL-17A dimer conformation
- Inhibits IL-17A-mediated signaling pathway
- Potential for research in inflammation and autoimmune diseases
- Exhibits good pharmacokinetic properties in rat models
- Offers high oral bioavailability
TARGETMOL CHEMICALS INC GSK2983559 ACTIVE METABO 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK2983559 active metabolite (RIPK2-IN-1) is a potent selective receptor-interacting protein-2 (RIP2) kinase inhibitor. purity: 98%
Medchemexpress LLC 2H-Indol-2-one, 1,3-dihydro-3-hydroxy-3-(2-oxo-2-phenylethyl)-1-(2-phenylethyl)- | 421578-93-0 | 99.8% | C24H21NO3 | 25 MG
GLP-1R modulator C5 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 1.59 ± 0.53 μM).
- Enhances GLP-1 binding to GLP-1R.
- Acts via a transmembrane site.
- High purity of 99.8%.
- White to off-white solid.
- Suitable for research applications.
![Medchemexpress LLC N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide | 476633-98-4 | 99.7% | 373.40 g·mol⁻1 | C22H19N3O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000287716.png-250.jpg)
Medchemexpress LLC N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide | 476633-98-4 | 99.7% | 373.40 g·mol⁻1 | C22H19N3O3 | 10 MG
Sirtuin modulator 6 is a small-molecule research compound that modulates sirtuin activity and is used in studies of lifespan, metabolic disorders, and neurodegenerative disease. The material is provided as a characterized solid with supporting batch documentation for research use in biochemical and cellular assays.
- High HPLC purity (99.7%).
- Molecular formula C22H19N3O3; molecular weight 373.40 g·mol⁻1.
- CAS registry number 476633-98-4 confirms chemical identity.
- Supplied in small research pack sizes suitable for assay preparation.
- Characterized by batch-specific COA and SDS for safety and quality data.
- Suitable for biochemical and cellular sirtuin pathway studies.
Medchemexpress LLC 4-Morpholineethanamine, N-[[4-[(2-chloro-6-fluorophenyl)methoxy]-3-methoxyphenyl]methyl]- | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 25 MG
GLP-1R modulator C16 is an allosteric modulator designed to enhance GLP-1 binding to GLP-1R via a transmembrane site. With an EC50 of 8.43 ± 3.82 μM, this compound is suitable for research applications.
- Enhances GLP-1 binding to GLP-1R
- Allosteric modulator
- High purity: 98.67%
- Soluble in DMSO
- Target: GCGR
- Pathway: GPCR/G Protein
- For research use only
Medchemexpress LLC IL-17 modulator 1 (disodium) | 2446803-91-2 | 98.4% | C28H35N6Na2O6P | 25 MG
IL-17 modulator 1 disodium is an orally active, highly efficacious small molecule IL-17 modulator. It is designed for research into diseases such as psoriasis, ankylosing spondylitis, and psoriatic arthritis. The disodium salt form provides enhanced water solubility and stability, making it suitable for various research applications.
- Orally active and highly efficacious small molecule
- Enhanced water solubility and stability
- Useful for research into psoriasis
- Useful for research into ankylosing spondylitis
- Useful for research into psoriatic arthritis
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 50 MG
GLP-1R modulator C16 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 8.43 ± 3.82 μM).
- Enhances GLP-1 binding to GLP-1R.
- Acts via a transmembrane site.
- High purity of 98.7% confirmed by LCMS.
- Recommended storage conditions for powder: -20°C for 3 years, 4°C for 2 years.
- Recommended storage conditions for in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC Fast garnet GBC sulfate salt | 101-89-3 | MFCD00011883 | 90.0% | 334.35 g·mol⁻¹ | C14H14N4O4S | 100 MG
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase used in histology and biochemical assays. It yields a red-violet azo precipitate at enzyme activity sites and is supplied in small pack sizes for research use, including 50 mg, 100 mg, and 250 mg. CAS 101-89-3; molecular weight 334.35 g·mol⁻¹.
- Chromogenic substrate for alkaline phosphatase staining and detection.
- Approximately 90% purity suitable for research applications.
- Produces a red-violet azo precipitate for clear visualization.
- Available in small pack sizes for laboratory use.
- Supplied as the sulfate salt with CAS number 101-89-3.