Thioureas
AdipoGen Suc-Leu-Leu-Val-Tyr-AMC
Chemical. CAS 94367-21-2. Formula C40H53N5O10. MW 763.9. Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases. Extinction 380nm. Emission 460 nm. This substrate is useful for inhibitor screening and kinetic analysis.
AdipoGen LY2835219
Chemical. CAS 1231930-82-7. Formula C27H32F2N8 . CH4O3S. MW 602.7. LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 CDK4 and CDK6 IC50s = 2 and 10 nM, respectively. Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds.
eMolecules 621-40-9 | N-(3-Methylphenyl)thiourea | Chem-Impex | MFCD00060451 | 166.240 | C8H10N2S | 98.000 | Cc1cccc(NC(N)=S)c1 | 1g | 386899236
N-(3-Methylphenyl)thiourea | Chem-Impex | 621-40-9 | MFCD00060451 | 166.240 | C8H10N2S | 98.000 | Cc1cccc(NC(N)=S)c1 | 1g | 386899236
eMolecules 6972-05-0 | 1,1-DIMETHYL-THIOUREA | AstaTech | MFCD00060474 | 104.170 | C3H8N2S | 95.000 | CN(C)C(N)=S | 0.25g | 402181171
1,1-DIMETHYL-THIOUREA | AstaTech | 6972-05-0 | MFCD00060474 | 104.170 | C3H8N2S | 95.000 | CN(C)C(N)=S | 0.25g | 402181171
eMolecules 62-56-6 | Thiourea | Chem-Impex | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 2.5kg | 386903163
Thiourea | Chem-Impex | 62-56-6 | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 2.5kg | 386903163
eMolecules 2954-52-1 | 5-Propyl-2-thiouracil | MFCD00057340 | 1g
Pharmablock | imidazo[12-a]pyridin-8-amine | 25mg | 551071250 | PB03596 | 73221-18-8 | MFCD06739233 | 133.154 | C7H7N3
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eMolecules (2-Hydroxyphenyl)thiourea | 1520-26-9 | MFCD00041159 | 1g
Combi-Blocks | (2-Hydroxyphenyl)thiourea | 1g | 232333878 | SH-5742 | 98.000 | 1520-26-9 | MFCD00041159 | 168.210 | C7H8N2OS
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eMolecules 62-56-6 | Thiourea | Chem-Impex | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 5kg | 342448903
Thiourea | Chem-Impex | 62-56-6 | MFCD00008067 | 76.120 | CH4N2S | 99.000 | NC(N)=S | 5kg | 342448903
![eMolecules 27231-36-3 | 2-Mercapto-5-methylbenzimidazole | Combi-Blocks | MFCD00010617 | 164.230 | C8H8N2S | 95.000 | Cc1ccc2[nH]c(S)nc2c1 | 1g | 290687361](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502184018.JPG-250.jpg)
eMolecules 27231-36-3 | 2-Mercapto-5-methylbenzimidazole | Combi-Blocks | MFCD00010617 | 164.230 | C8H8N2S | 95.000 | Cc1ccc2[nH]c(S)nc2c1 | 1g | 290687361
2-Mercapto-5-methylbenzimidazole | Combi-Blocks | 27231-36-3 | MFCD00010617 | 164.230 | C8H8N2S | 95.000 | Cc1ccc2[nH]c(S)nc2c1 | 1g | 290687361
AdipoGen 4-Methylumbelliferone
Chemical. CAS 90-33-5. Formula C10H8O3. MW 176.17. 4-Methylumbelliferone 4-MU is a selective inhibitor of hyaluronan HA by depletion of UDP-glucuronic acid, the common substrate for HA synthesis and downregulation of hyaluronan synthase 2 and 3, MMP2 and MMP9. Since hyaluronan HA is a major component of the extracellular matrix that is synthesized in excess in cancer tissues, 4-MU has been shown to have anti-cancer activity and is involved in angiogenesis, invasion and metastasis of cancer. Fluorescent pH indicator, that is highly fluorescent in alkaline solution. Exhibits a blue fluorescence at pH7. The fluorescence intensity is pH dependent and increases to a maximum at pH10 plateau above pH10. The fluorescence at pH10.3 is approximately 100 times as intense as at pH7. Spectral data lambdaex=360nm lambdaem=448nm pH > 9.