Cinnamic acids and derivatives
Medchemexpress LLC Curcumin 5-8 | 890984-26-6 | 98.58% | 339.39 | 100 MG
Curcumin 5-8 is a potent, orally active curcumin analog. It inhibits lipid droplet formation, increases autophagy, and inhibits apoptosis. It also improves insulin resistance and insulin sensitivity, and has been shown to ameliorate nonalcoholic fatty liver disease in mice.
- Decreases PA-induced SREBP1 expression and increases Bcl2/BAX expression in AML12 cells.
- Exhibits cytotoxic activity against B16, HUVEC, SiHa, U-87MG ATCC, and Vero cell lines.
- Ameliorates insulin resistance and hepatic steatosis in HFD-induced obese mice.
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 50 MG
Ferulic acid 4-O-sulfate is a metabolite of Ferulic acid that relaxes arteries and lowers blood pressure in mice. This compound causes significant concentration-dependent relaxations in mouse aorta, femoral and saphenous arteries.
- Relaxes arteries and lowers blood pressure
- Suitable for in vitro and in vivo studies
- Significant concentration-dependent relaxations in mouse arteries
Accela Chembio Inc 4-(dimethylamino)cinnamic Acid | 25g | 1552-96-1 | MFCD00004397 | 97+% | Shelf Life: 1260 Days | Light Sensitive
4-(dimethylamino)cinnamic Acid | 25g | 1552-96-1 | MFCD00004397 | 97+% | Shelf Life: 1260 Days | Light Sensitive
Medchemexpress LLC M-coumaric acid | 588-30-7 | 99.8% | 164.16 | 1 ML
m-Coumaric acid is an endogenous metabolite and polyphenol that is formed from caffeic acid by gut microflora. It is a BBB-penetrant metabolite of chlorogenic acid and can stimulate cerebral nerves and evoke neurite outgrowth in hippocampal neuronal cells, promoting neuronal differentiation. It has also been shown to increase spontaneous locomotor activity in mice.
- Inhibits the oxidation of L-dopa by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Stimulates cerebral nerves in vitro
- Promotes neuronal differentiation
- Increases spontaneous locomotor activity
Medchemexpress LLC m-Coumaric acid | 588-30-7 | >99.8% | 164.16 | 500 MG
m-Coumaric acid | 588-30-7 | >99.8% | 164.16 | 500 MG
Selleck Chemical LLC Tyrphostin AG 879 S2816-25mg
Tyrphostin AG 879 potently inhibits HER2/ErbB2 with IC50 of 1 M 100- and 500-fold higher selective to ErbB2 than PDGFR and EGFR
Medchemexpress LLC 2-Propenoic acid, 3-(4-hydroxyphenyl)-,(2E)- | 501-98-4 | 164.16 | 1 G
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. It inhibits cell proliferation, promotes apoptosis, and exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities. It is for research use only.
- Inhibits cell proliferation.
- Promotes apoptosis.
- Exhibits antibacterial activity.
- Exhibits anti-inflammatory activity.
- Exhibits antioxidant activity.
- Exhibits anti-tumor activities.
Medchemexpress LLC p-Coumaric acid (trans-4-Hydroxycinnamic acid) | 501-98-4 | 164.16 | 500 MG
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity that exhibits several biological activities:
- Inhibits cell proliferation
- Promotes apoptosis
- Has antibacterial activity
- Has anti-inflammatory activity
- Has antioxidant activity
- Has anti-tumor activities