Cinnamic acids and derivatives
Cayman Chemical Plnt TurmerIc CurcumIn 10g
A yellow pigment with diverse biological activities; inhibits NO production (IC50 = 6 μM) and reduces iNOS activity in LPS-stimulated RAW 264.7 cells; inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells; decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis; prevents ovalbumin-induced accumulation of 3-NT in mouse heart; reduces TPA-induced tumor formation in mouse skin (1-10 μmol); reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-NQO in rats
eMolecules 2-(3'-Fluorobenzyloxy)phenylboronic acid | 871126-24-8 | MFCD07784392 | 5g
Combi-Blocks | 2-(3'-Fluorobenzyloxy)phenylboronic acid | 5g | 335356093 | BB-8006 | 98.000 | 871126-24-8 | MFCD07784392 | 246.040 | C13H12BFO3
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Medchemexpress LLC 2-chlorocinnamic acid | 3752-25-8 | MFCD00004372 | 99.8% | 182.60 g/mol | C9H7ClO2 | 10 G
2-Chlorocinnamic acid (CAS 3752-25-8) is the 2-chloro analogue of cinnamic acid, present predominantly as the trans (E) isomer. It is supplied as a research-grade chemical for use as a building block, synthetic intermediate, and analytical reference in organic and medicinal chemistry; molecular formula C9H7ClO2, molar mass 182.60 g/mol.
- High purity (≈99.8%).
- Predominantly trans (E) isomer.
- Crystalline solid; easy to handle and store.
- Used as a synthetic building block and intermediate.
- Suitable as an analytical reference standard and for method development.
- Available as a solid and as a 10 mM solution in DMSO.
- Documentation available: datasheet, certificate of analysis, and safety data sheet.
eMolecules 4-(4-Fluorobenzyloxy)chlorobenzene | 332-04-7 | MFCD05105278 | 1g
Oakwood Chemical | 4-(4-Fluorobenzyloxy)chlorobenzene | 1g | 537680719 | 023259 | | 332-04-7 | MFCD05105278 | 236.670 | C13H10ClFO
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TARGETMOL CHEMICALS INC BISDEMETHOXYCURCUMIN 50MG
Also available in 5 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis interacting with 1(alpha) 25-dihydroxy vitamin D3 to stimulate amyloid-(beta) clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300 suppressing the Wnt/(beta)-catenin pathway and inhibits LPS induction of iNOS expression [3]. purity: 99%
