Cinnamic acids and derivatives
Medchemexpress LLC M-carboxycinnamic acid bishydroxamide | 174664-65-4 | MFCD03453553 | 98.0% | 222.20 g·mol^-1 | C10H10N2O4 | 5 MG
m-Carboxycinnamic acid bishydroxamide (CBHA) is a small-molecule histone deacetylase (HDAC) inhibitor supplied for research use. It is used in biochemical and cellular assays to probe chromatin regulation, gene expression, and apoptosis pathways, with reported activity against HDAC1 and HDAC3.
- potent HDAC1 and HDAC3 inhibition (reported ID50 ≈ 10 nM and 70 nM)
- high purity suitable for biochemical assays (98.0%)
- available in small sample sizes for screening and method development
- stable as a powder when stored at low temperature
- compatible with in vitro cellular and enzymatic studies
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 25 G
4-Methoxycinnamic acid is detected as a natural phenylpropanoid in A. preissii. For optimal preservation, store the powder at -20°C for up to 3 years or 4°C for up to 2 years. If in solvent, store at -80°C for 2 years or -20°C for 1 year. Keep the container tightly sealed in a cool, well-ventilated area, away from direct sunlight and sources of ignition. Shipping is at room temperature if the duration is less than 2 weeks.
- Endogenous metabolite
- Structure classification: Ketones, aldehydes, acids
- Initial source: Endogenous metabolite
- Purity: 99.87%
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.07% | 274.25 | 50 MG
Ferulic acid 4-O-sulfate is a metabolite of Ferulic acid that relaxes arteries and lowers blood pressure in mice. This compound causes significant concentration-dependent relaxations in mouse aorta, femoral and saphenous arteries.
- Relaxes arteries and lowers blood pressure
- Suitable for in vitro and in vivo studies
- Significant concentration-dependent relaxations in mouse arteries
Medchemexpress LLC Tyrphostin 25 | 118409-58-8 | MFCD00133900 | 99.0% | 202.17 | C10H6N2O3 | 10 MG
Tyrphostin 25 (AG82) is a small-molecule research compound that selectively inhibits epidermal growth factor receptor (EGFR) tyrosine kinase and acts as a GPR35 agonist. It prevents EGFR autophosphorylation and reduces EGF-induced cell migration in vitro. Supplied as a yellow to brown solid with high analytical purity for laboratory research; for research use only.
- High purity: 99.0%.
- Molecular weight: 202.17 g/mol.
- Chemical formula: C10H6N2O3.
- Physical form: solid, yellow to brown powder.
- Biological activity: EGFR IC50 ≈ 3 μM (A431 cells); GPR35 EC50 ≈ 5.3 μM.
- Storage: powder -20°C (stable for years); in solution -80°C (months).
- SDS available in multiple languages.
- Intended use: for research use only.
Cayman Chemical p-CoumarIc AcId 50g
A hydroxy derivative of cinnamic acid that can be found in a variety of edible plants that is reported to have antioxidant, anti-inflammatory, and antimicrobial activity
Medchemexpress LLC Tyrphostin AG 528 | 133550-49-9 | MFCD01076474 | 98.0% | 306.32 g·mol^-1 | C18H14N2O3 | 25 MG
Tyrphostin AG 528 is a small-molecule protein tyrosine kinase inhibitor used as a research reagent to probe EGFR and ErbB2 (HER2) signaling pathways. It is supplied as a high-purity solid for biochemical and cellular studies.
- Inhibits EGFR and ErbB2 with reported IC50s of 4.9 μM and 2.1 μM.
- High purity (98.0%) suitable for laboratory research.
- Supplied as a solid, light yellow to yellow in color.
- Molecular weight 306.32 g·mol⁻¹; formula C18H14N2O3.
- Available in small research quantities, including 25 mg packaging.
Sigma Aldrich Fine Chemicals Biosciences p-Coumaric acid-1,2,3-13C3 99 atom % 13C, 99% (CP) | 1261170-80-2 | 5MG
p-Coumaric acid-1,2,3-13C3 99 atom % 13C, 99% (CP) | Purity: 99% (CP) | Mol Wt: 167.14 | 1261170-80-2 | 5MG
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | MFCD02605317 | 99.82% | C14H11FO2 | 50 G
4-(3-Fluorobenzyloxy)benzaldehyde is a drug intermediate used for the synthesis of various active compounds. This product is provided as a solid and is intended for research use only.
- Drug intermediate for synthesis of active compounds
- Provided as a solid
- For research use only
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | 99.8% | C14H11FO2 | 100 G
4-(3-Fluorobenzyloxy)benzaldehyde is a chemical compound that serves as a drug intermediate. It is used in the synthesis of various active compounds for research purposes.
- Solid appearance
- Functions as a drug intermediate
- Suitable for the synthesis of active compounds
- For research use only
- Shipped at room temperature in continental US
- Store at 4°C under nitrogen
- When in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | 99.8% | C14H11FO2 | 10 G
4-(3-Fluorobenzyloxy)benzaldehyde is a drug intermediate for synthesis of various active compounds.
- High purity: 99.82%
- Available in various sizes
- For research use only
- Specific storage conditions: 4°C, stored under nitrogen (solid); -80°C for 6 months or -20°C for 1 month in solvent (under nitrogen)
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | 99.9% | 164.16 | 1 G
2-Hydroxycinnamic acid is a phenolic acid possessing antimicrobial and antioxidant properties. It exhibits antimicrobial activity against Staphylococcus aureus without succumbing to drug resistance. Furthermore, it demonstrates inhibitory effects on HIV/SARS-CoV S pseudovirus infection with an IC50 of 0.3 mM. The compound also presents neuroprotective and antitumor activities.
- Antimicrobial properties: Effective against Staphylococcus aureus, including drug-resistant strains.
- Antioxidant properties: Acts as an antioxidant.
- Antiviral activity: Inhibits infection of HIV/SARS-CoV S pseudovirus.
- Neuroprotective activity: Offers protective effects on neurons.
- Antitumor activity: Shows potential in combating tumors.
![Medchemexpress LLC Propanedinitrile, 2-[(3,4-dihydroxy-5-nitrophenyl)methylene] | 116313-73-6 | MFCD00236451 | 98.7% | 231.16 g/mol | C10H5N3O4 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000248008.png-250.jpg)
Medchemexpress LLC Propanedinitrile, 2-[(3,4-dihydroxy-5-nitrophenyl)methylene] | 116313-73-6 | MFCD00236451 | 98.7% | 231.16 g/mol | C10H5N3O4 | 5 MG
Tyrphostin AG 1288 is a small-molecule tyrosine kinase inhibitor used in research to modulate signaling pathways. Supplied as a light yellow solid, it inhibits ICAM1 expression and TNFα-mediated cytotoxicity in vitro and is characterized by formula C10H5N3O4, molecular weight 231.16 g/mol, and typical purity of approximately 98.7%.
- Potent tyrosine kinase inhibition in cellular assays.
- Inhibits ICAM1 expression and TNFα-mediated cytotoxicity.
- High purity suitable for biochemical and cellular studies.
- Available in small milligram-scale packages for laboratory use.
- Solid form with defined appearance for straightforward handling.
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.8% | C10H10O2 | 50 G
3-Methylcinnamic acid is a drug intermediate used for the synthesis of various active compounds. This product is for research use only and is not sold to patients.
- Used for the synthesis of various active compounds.
- Appears as a white to off-white solid.
- Intended for research use only.
- Purity of 99.77%.
- Storage as powder at -20°C for 3 years or 4°C for 2 years.
- Storage in solvent at -80°C for 6 months or -20°C for 1 month.
TARGETMOL CHEMICALS INC Tipifarnib S enantiomer 5MG
Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50 0.6 nM). Purity 99.05%
Selleck Chemical LLC AMG-458 S2747-5mg
AMG 458 is a potent c-Met inhibitor with Ki of 1 2 nM 350-fold selectivity for c-Met than VEGFR2 in cells