Cinnamic acids and derivatives
eMolecules 3-Isobutoxy-4-methoxyphenylboronic acid | 1629972-11-7 | MFCD12756417 | 1g
Combi-Blocks | 3-Isobutoxy-4-methoxyphenylboronic acid | 1g | 117524383 | BB-6003 | 98.000 | 1629972-11-7 | MFCD12756417 | 224.060 | C11H17BO4
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![eMolecules Medchem Express / MRL-494 (hydrochloride) / 5mg / 552386588 / HY-128773A / / 2699937-04-5 / [null] / 659.130 / C26H36ClFN16O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502476283.JPG-250.jpg)
eMolecules Medchem Express / MRL-494 (hydrochloride) / 5mg / 552386588 / HY-128773A / / 2699937-04-5 / [null] / 659.130 / C26H36ClFN16O2
Medchem Express / MRL-494 (hydrochloride) / 5mg / 552386588 / HY-128773A / / 2699937-04-5 / [null] / 659.130 / C26H36ClFN16O2
Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | >98.0% | C19H20O2 | 10MG
(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one (CAS 100667-52-5) is a diarylheptanoid research chemical used as a biochemical reagent for laboratory studies. It appears as a white to off-white solid and is characterized by molecular formula C19H20O2 and a molecular weight of 280.4 g/mol. The compound is provided in small research-scale quantities for analytical, assay, and synthetic applications.
- High purity (>98.0%).
- Accurate molecular formula C19H20O2.
- Suitable for assay and analytical use in research settings.
- Supplied in small milligram package sizes for laboratory workflows.
- Includes standard structural identifiers for cheminformatics (SMILES, InChIKey).
Apexbio Technology LLC Tyrphostin 9 10537-47-0 25mg
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes
![Medchemexpress LLC Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester | 1439366-88-7 | 99.7% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231161.png-250.jpg)
Medchemexpress LLC Carbamic acid, N-[(2R,3S)-2-methyl-4-oxo-3-oxetanyl]-, 5-phenylpentyl ester | 1439366-88-7 | 99.7% | 1 ML
ARN 077 (enantiomer) is the less-active stereoisomer of ARN 077 (also reported as URB913 enantiomer). It is supplied for research use and reported to inhibit rat NAAA with an IC50 of 3.53 μM for the less-active enantiomer. The compound is offered as a 10 mM solution in DMSO (1 mL) and as solid quantities for laboratory use.
- Supplied as 10 mM solution in DMSO, 1 mL, and as solids for flexibility in experiments.
- High reported purity (≈99.7%), suitable for research applications.
- Molecular formula C16H21NO4, molecular weight 291.34 g/mol.
- Reported CAS number 1439366-88-7 for unambiguous identification.
- Intended for research use only; not for human or diagnostic use.
Apexbio Technology LLC Entacapone 130929-57-6 10mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Apexbio Technology LLC Curcumin(Synonyms: Diferuloylmethane, Turmeric yellow, Natural yellow 3, CI 75300), 10mM (in 1mL DMSO), CAS: 458-37-7.
Curcumin (CAS 458-37-7) is a natural small molecule known to inhibit tyrosinase activity with an IC50 of 47 M It modulates multiple signaling pathways involved in tumorigenesis and inflammation influencing transcription factors growth factors cytokines receptors and enzymes Clinical trials at Phase I reported no observed toxicity at doses up to 12 g/day however oral bioavailability is limited ( 1% in Phase I/II studies) Additionally curcumin demonstrates potential for Alzheimer s research as evidenced by reducing beta-amyloid (A 40 A 42) production via downregulating presenilin-1 and GSK-3 in SH-SY5Y neuroblastoma cells
Apexbio Technology LLC Entacapone 130929-57-6 10mM (in 1mL DMSO)
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
TARGETMOL CHEMICALS INC ENTACAPONE 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT). purity: 99%
Cayman Chemical Plnt TurmerIc CurcumIn 5g
A yellow pigment with diverse biological activities; inhibits NO production (IC50 = 6 μM) and reduces iNOS activity in LPS-stimulated RAW 264.7 cells; inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells; decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis; prevents ovalbumin-induced accumulation of 3-NT in mouse heart; reduces TPA-induced tumor formation in mouse skin (1-10 μmol); reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-NQO in rats
Apexbio Technology LLC Entacapone sodium salt 1047659-02-8 100mg
Entacapone sodium salt (CAS 1047659-02-8) is a nitrocatechol small molecule that acts as a selective and reversible inhibitor of catechol-O-methyltransferase (COMT) a Mg2 -dependent enzyme involved in the metabolism of catecholamines and related compounds In biochemical assays entacapone exhibits an IC50 of 20 1 nM and a Ki of 10 7 nM for COMT inhibition The presence of a nitro group ortho to the hydroxyl group in its structure contributes to its inhibitory potency Entacapone has been widely used in research focused on Parkinson s disease particularly to study the modulation of levodopa bioavailability and pharmacokinetics