Coumarins and derivatives
![Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261568.png-250.jpg)
Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG
Palomid 529 is a small-molecule research inhibitor that targets both mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2), modulating the PI3K/Akt/mTOR signaling pathway. It has been used in preclinical studies and early clinical research to reduce tumor growth, angiogenesis, and vascular permeability, and has been investigated for neovascular age-related macular degeneration.
- Dual inhibition of mTORC1 and mTORC2.
- Documented in peer-reviewed literature and public chemical databases.
- High reported purity suitable for analytical use.
- Suitable as an analytical standard and research reagent.
- Provided with batch-specific certificate of analysis data.
TARGETMOL CHEMICALS INC 7-ACETOXY-4-METHYLCOUMAR 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media a cell membrane environmental mimic to study superoxide and related oxyl-radical reactions of model biological membranes dispersed in aqueous media. Due to the ability for AchE to cleave and activate 7-Acetoxy-4-methylcoumarin the fluorogenic substrate has been used to study the AchE inhibitor Tacrine·HCl (sc-200172). The compound has also been isolated from Trigonella foenum graceum. purity: 88%