Linear 1 3-diarylpropanoids
Medchemexpress LLC Xanthohumol D | 274675-25-1 | 370.40 | 1 MG
Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with an IC50 value of 110 μM. It binds to the active site of QR-2 and shows antiproliferative activity on human cancer cell lines in vitro.
- Inhibitor of quinone reductase-2 (QR-2).
- Binds to the active site of QR-2.
- Shows antiproliferative activity on human cancer cell lines in vitro.
Apexbio Technology LLC Phloretin is a dihydrochalcone, a type of natural phenols. 60-82-2. MFCD00002288
Phloretin is a dihydrochalcone, a type of natural phenols. 60-82-2. MFCD00002288
Medchemexpress LLC Naringin Dihydrochalcone | 18916-17-1 | 99.2% | 582.55 | 5 G
Naringin Dihydrochalcone is an artificial sweetener synthesized from naringin, a flavanone glycoside naturally found in citrus fruits like tomatoes and grapefruits. It demonstrates various biological properties, including antioxidant, anti-inflammatory, and antiapoptotic effects, and is known to suppress the NF-κB signaling pathway.
- Artificial sweetener.
- Derived from naringin, a flavanone glycoside.
- Exhibits antioxidant, anti-inflammatory, and antiapoptotic activities.
- Suppresses NF-κB signaling pathway.
- Inhibits high glucose-induced proliferation and oxidative stress in HBZY-1 cells.
- Induces autophagic cell death in AGS cancer cells.
- Protects PC12 cells from neurotoxicity and enhances antioxidant defense.
- Alleviates renal injury, collagen deposition, and fibrosis in diabetic rats.
- Improves learning, memory, and insulin signaling in high-fat diet-induced obese mice.
Apexbio Technology LLC Phloretin 60-82-2 10mM (in 1mL DMSO)
Phloretin (CAS 60-82-2) is a naturally occurring dihydrochalcone phenolic compound derived primarily from apple leaves and Manchurian apricot It functions as an inhibitor of sodium-glucose linked transporters (SGLT1 and SGLT2) proteins involved in glucose uptake and reabsorption in intestinal and renal tissues Phloretin inhibits glucose uptake via these transporters exhibiting an IC50 of approximately 49 12 M In cell-based studies it enhances lipolysis increases AMP-activated protein kinase (AMPK) phosphorylation and suppresses adipogenic transcription factors and MAPK signaling Animal research demonstrates that oral administration of Phloretin reduces blood glucose and improves lipid profiles in diabetic mouse models highlighting its utility in metabolic research
Medchemexpress LLC Dihydrochalcone 25g | 1083-30-3 | 210.27 g/mol | C15H14O | 25 G
Dihydrochalcone (CAS 1083-30-3) is a small-molecule research reagent supplied as a high-purity solid for in vitro and analytical applications.
- High purity ≥98%.
- Molecular formula C15H14O.
- Molecular weight 210.27 g/mol.
- Suitable for in vitro biochemical assays and as an analytical reference.
- Available in a 25 G pack for laboratory use.
eMolecules 110231-30-6 | Diphenyl-1-pyrenylphosphine | Medchem Express | MFCD00278755 | 386.434 | C28H19Pc1ccc(cc1)P(c1ccccc1)c1ccc2ccc3cccc4ccc1c2c34 | 25mg | 795078557
Diphenyl-1-pyrenylphosphine | Medchem Express | 110231-30-6 | MFCD00278755 | 386.434 | C28H19Pc1ccc(cc1)P(c1ccccc1)c1ccc2ccc3cccc4ccc1c2c34 | 25mg | 795078557
TARGETMOL CHEMICALS INC Naringenin 1G
Also available in 1 mL, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. This substance has also been shown to repair DNA. Purity 98.81%
Medchemexpress LLC Chalcone dibromide | 611-91-6 | MFCD00017861 | 95.0% | 368.06 g·mol⁻1 | C15H12Br2O | 1 ML
Chalcone dibromide (CAS 611-91-6) is a dibrominated chalcone derivative supplied as a ready-to-use 10 mM solution in DMSO for research and synthetic applications. It is used as a synthon in the synthesis of bioactive heterocycles and has reported antioxidant and anticancer-related activity; product documentation includes datasheet, COA, and SDS.
- Supplied as a 10 mM solution in DMSO (1 mL).
- Molecular formula C15H12Br2O and molecular weight 368.06 g·mol⁻1.
- Purity 95.0%.
- Useful synthon for synthesis of pyrazolines, hydroxy pyrazolines, and isoxazoles.
- Available as a solid (100 mg) and larger sizes by quote.
- Documentation includes datasheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC (±)-Naringenin | 67604-48-2 | MFCD00006844 | 99.83% | 272.26 | 1 ML
(±)-Naringenin is an orally available anti-inflammatory agent that regulates acute and chronic inflammation, and exhibits antioxidant, neuroprotective, liver-protective, and anti-cancer effects. It promotes vasodilation and protects against experimental colitis by inhibiting Toll-like receptor 4/NF-κB signaling, useful in studies of sepsis, fulminant hepatitis, fibrosis, and cancer. It appears as an off-white to light yellow solid.
- Regulates acute and chronic inflammation.
- Antioxidant, neuroprotective, liver-protective, and anti-cancer effects.
- Promotes vasodilation.
- Protects against experimental colitis.
- Useful in sepsis, hepatitis, fibrosis, and cancer research.
- Orally available.
Medchemexpress LLC AKT inhibitor VIII | 612847-09-3 | MFCD23843802 | 99.0% | 551.64 g/mol | C34H29N7O | 100 MG
AKT inhibitor VIII is a cell-permeable, reversible allosteric inhibitor of Akt kinases used as a research reagent to probe PI3K/Akt signaling pathways. It is supplied as a light yellow solid for laboratory use.
- Allosteric, reversible Akt inhibitor.
- Isoform-selective activity with greater potency for Akt1 and Akt2.
- Reported IC50 values: Akt1 = 58 nM, Akt2 = 210 nM.
- Molecular formula C34H29N7O; molecular weight 551.64 g/mol.
- High reported purity (~99%).
- Supplied as a light yellow solid with recommended storage for powder at -20°C or 4°C depending on duration.