Linear 1 3-diarylpropanoids
Apexbio Technology LLC AKT inhibitor VIII(Synonyms: AKTi-1/2, Akt Inhibitor VIII, AKTi VIII, Akt kinase inhibitor VIII, Isozyme-selective AKT inhibitor VIII), 10mM (in 1mL DMSO), CAS: 612847-09-3.
AKT inhibitor VIII (CAS 612847-09-3) is a cell-permeable reversible inhibitor targeting Akt isoforms Akt1 Akt2 and Akt3 exhibiting IC50 values of 58 nM 210 nM and 2119 nM respectively It acts by suppressing Akt signaling as demonstrated by its ability to inhibit IGF-1-stimulated Akt phosphorylation and to reduce PRAS40 phosphorylation in PC12 cells In MCF-7 breast cancer cells AKT inhibitor VIII enhances the antiproliferative activity of furanodiene augmenting its effects on Akt/p-Akt downregulation and promoting PARP cleavage This compound is valuable for exploring Akt-dependent signaling pathways in oncology research and neuronal cell biology studies
Medchemexpress LLC AKT inhibitor VIII | 612847-09-3 | MFCD23843802 | 99.0% | 551.64 g/mol | C34H29N7O | 100 MG
AKT inhibitor VIII is a cell-permeable, reversible allosteric inhibitor of Akt kinases used as a research reagent to probe PI3K/Akt signaling pathways. It is supplied as a light yellow solid for laboratory use.
- Allosteric, reversible Akt inhibitor.
- Isoform-selective activity with greater potency for Akt1 and Akt2.
- Reported IC50 values: Akt1 = 58 nM, Akt2 = 210 nM.
- Molecular formula C34H29N7O; molecular weight 551.64 g/mol.
- High reported purity (~99%).
- Supplied as a light yellow solid with recommended storage for powder at -20°C or 4°C depending on duration.
Apexbio Technology LLC trans-13-docosenoic acid 506-33-2 5mg
trans-13-docosenoic acid is a long-chain monounsaturated fatty acid It is used experimentally to study lipid metabolism pathways cellular membrane processes and lipid signaling mechanisms in biological systems trans-13-docosenoic acid also serves as an analytical standard in lipidomics studies to identify and quantify fatty acid profiles in biological samples Based on these properties trans-13-docosenoic acid holds research potential in the development of lipid-based delivery systems surfactants and topical pharmaceutical and cosmetic preparations
Selleck Chemical LLC Xanthohumol
Xanthohumol a prenylated chalcone from hop inhibits COX-1 and COX-2 activity and shows chemopreventive effects Xanthohumol inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 M Xanthohumol is also a potent antiviral agent against a series of DNA and RNA viruses Xanthohumol induces growth inhibition and apoptosis in cancer cells Phase 1
Selleck Chemical LLC Xanthohumol
Xanthohumol a prenylated chalcone from hop inhibits COX-1 and COX-2 activity and shows chemopreventive effects Xanthohumol inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 M Xanthohumol is also a potent antiviral agent against a series of DNA and RNA viruses Xanthohumol induces growth inhibition and apoptosis in cancer cells Phase 1
Medchemexpress LLC Tetra(p-bromophenyl)porphyrin | 29162-73-0 | 95.0% | 930.32 | C44H26Br4N4 | 5 G
Tetra(p-bromophenyl)porphyrin is a brominated tetrakisphenylporphyrin used as a fluorescent dye and as a synthetic intermediate in porphyrin chemistry. It is employed as a porphyrin scaffold for derivatization and photophysical studies.
- Fluorescent tetrakisphenylporphyrin with four p-bromophenyl groups.
- CAS number 29162-73-0 and formula C44H26Br4N4.
- Molecular weight 930.32 g·mol-1.
- Light blue to blue solid, purity ~95.0%.
- Suitable as a building block for perfluoroalkyl-substituted porphyrins and other derivatives.
- Store protected from light and under inert atmosphere; cold storage recommended for solutions.
TARGETMOL CHEMICALS INC Xanthohumol 10MG
Also available in 1 mL, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Purity 99.18%
Apexbio Technology LLC trans-13-docosenoic acid 506-33-2 10mg
trans-13-docosenoic acid is a long-chain monounsaturated fatty acid It is used experimentally to study lipid metabolism pathways cellular membrane processes and lipid signaling mechanisms in biological systems trans-13-docosenoic acid also serves as an analytical standard in lipidomics studies to identify and quantify fatty acid profiles in biological samples Based on these properties trans-13-docosenoic acid holds research potential in the development of lipid-based delivery systems surfactants and topical pharmaceutical and cosmetic preparations
Medchemexpress LLC Trans-aconitic acid | 4023-65-8 | MFCD00002721 | ≥98.0% | 174.11 | C6H6O6 | 10 MG
trans-aconitic acid (CAS 4023-65-8) is an analytical reference standard for metabolite analysis and method validation. It is supplied as a white to off-white solid with molecular formula C6H6O6 and molecular weight 174.11, intended for research and analytical applications.
- Purity (NMR) ≥98.0%.
- White to off-white solid suitable for analytical use.
- Stable as a powder: -20°C (3 years), 4°C (2 years).
- Stable in solvent under cold storage: -80°C (6 months), -20°C (1 month).
- Suitable for reference, calibration, and method development.
Selleck Chemical LLC Avobenzone S1904-200mg
Avobenzone (Butyl methoxydibenzoylmethane BF2AVB) is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative