Macrolide lactams

Medchemexpress LLC Tacrolimus monohydrate | 109581-93-3 | MFCD11045918 | 99.9% | 822.03 g·mol⁻¹ | C44H71NO13 | 5 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

Tacrolimus monohydrate is a macrocyclic lactone immunosuppressant reagent that binds FK506 binding protein (FKBP) and inhibits calcineurin phosphatase, suppressing T-cell signaling and IL-2 transcription for in vitro immunology and biochemical studies.

• High purity suitable for research applications.
• Molecular formula C44H71NO13; molecular weight 822.03 g·mol⁻¹.
• CAS number 109581-93-3 for unambiguous identification.
• Store protected from light at 4°C; in solution store at -80°C for long-term stability.
• Commonly used in assays targeting calcineurin and FKBP-mediated pathways.

Medchemexpress LLC Fk-453 | 121524-18-3 | 99.2% | 375.46 g·mol⁻¹ | C23H25N3O2 | 100 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

FK 453 is a potent, selective adenosine A1 receptor antagonist (IC50 = 17.2 nM) supplied as a high-purity small-molecule powder for research use. It includes recommended storage and solvent handling guidance to support reproducible in vitro assays.

• High purity 99.2%.
• Potent adenosine A1 receptor antagonist, IC50 17.2 nM.
• Molecular weight 375.46 g·mol⁻¹; formula C23H25N3O2.
• Recommended solvent DMSO at 100 mg/mL; may require ultrasonication.
• Storage: powder -20°C (up to 3 years), 4°C (up to 2 years); in solvent -80°C (6 months), -20°C (1 month).
• Suitable for in vitro pharmacology and receptor binding studies.

Medchemexpress LLC FK 453 | 121524-18-3 | 99.2% | 375.46 | C23H25N3O2 | 25 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

FK 453 is a research-use adenosine A1 receptor antagonist (compound 1d) characterized by potent activity and a defined chemical profile. It exhibits an IC50 of 17.2 nM and is supplied as a high-purity powder with recommended storage conditions for both powder and solution forms.

• Potent, selective adenosine A1 receptor antagonist (IC50 = 17.2 nM).
• High purity: 99.2%.
• Molecular formula C23H25N3O2 and molecular weight 375.46.
• Available in multiple small-scale package sizes, including 25 mg.
• Storage recommended as powder at -20°C (3 years) or 4°C (2 years).
• In solvent storage guidance: -80°C (6 months) or -20°C (1 month).
• For research use only; not for human or clinical use.