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Derived from formic acid, formamide is the simplest monocarboxylic acid amide. Available in various quantities, it is used as a solvent for ionic compounds, resins, and plasticizers and in the manufacture of drugs, herbicides, pesticides, and hydrocyanic acid.
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Formamide-15N is the 15N labeled Formamide (HY-Y0842) Formamide is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions Formamide can also be used as a decalcifying agent for rat cardiac cells Additionally formamide is widely used as a solvent or chemical raw material for ion compounds resins and plasticizers [1][2][3][4][5][6][7]
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Formamide (CAS No 75-12-7) is a versatile compound extensively used in biomedical research due to its ability to act as a solvent and its role in stabilizing nucleic acids Originating from carbonyl and amine it facilitates reactions involving hydrogen bond formation Its mechanism of action often involves interaction with nucleic acid structures influencing various biological pathways In vitro activity generally falls within the nanomolar to low micromolar range making it valuable for precise molecular studies Formamide is frequently employed in cell models and animal studies to explore genetic manipulation and gene expression effects It serves as a critical component in drug screening processes aiding in the evaluation of therapeutic candidates Experimental concentrations typically depend on the specific research design ensuring adaptability across diverse experiments
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Formamide deionized (Methanamide deionizde) is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions Formamide deionized can also be used as a decalcifying agent for rat cardiac cells Additionally Formamide deionized is widely used as a solvent or chemical raw material for ion compounds resins and plasticizers[1][2][3][4][5][6][7]
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It is a clear liquid amide derived from formic acid and can be used as cryoprotectant and gel-stabilizer. It is known to destabilize nucleic acid duplexes, making it useful for preparing hybridization buffers for RNA and DNA applications. Technical Information:Conductivity (µmhos): <100Abs. @ 280nm: <0.5Freezing Range: 1-3°Iron: <0.0005%Copper: <0.00001%Lead: <0.00005%ZInc: <0.00005%RNase/DNase: None DetectedAppearance: LiquidAtomic Number: Not available.Boiling Point : 210 °C(lit.)ChEBI : Not available.Crystal_Structure : Not available.Density : 1.134 g/mL at 25 °C(lit.)Electron Configuration : Not available.InChI : Not available.InChIKey : Not available.Ionization Energy : Not available.Melting Point: 2-3 °C(lit.)Molar Mass: Not available.NFPA 704: Not available.RTECS Number: LQ0525000Synonyms: Amide C1, Formic amide
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It is a clear liquid amide derived from formic acid and can be used as cryoprotectant and gel-stabilizer. It is known to destabilize nucleic acid duplexes, making it useful for preparing hybridization buffers for RNA and DNA applications. Technical Information:Conductivity (µmhos): <100Abs. @ 280nm: <0.5Freezing Range: 1-3°Iron: <0.0005%Copper: <0.00001%Lead: <0.00005%ZInc: <0.00005%RNase/DNase: None DetectedAppearance: LiquidAtomic Number: Not available.Boiling Point : 210 °C(lit.)ChEBI : Not available.Crystal_Structure : Not available.Density : 1.134 g/mL at 25 °C(lit.)Electron Configuration : Not available.InChI : Not available.InChIKey : Not available.Ionization Energy : Not available.Melting Point: 2-3 °C(lit.)Molar Mass: Not available.NFPA 704: Not available.RTECS Number: LQ0525000Synonyms: Amide C1, Formic amide
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