Methyl Isobutyl Ketone
Apexbio Technology LLC Musk ketone 81-14-1 500mg
Musk ketone (CAS 81-14-1) is a small-molecule compound recognized for its modulatory effects on cytochrome P450 enzymes acting as an inducer in cellular systems In Hep G2 cell studies musk ketone has demonstrated mutagenic and cytotoxic properties Notably it promotes neural stem cell proliferation and differentiation under cerebral ischemic conditions primarily via activation of the PI3K/Akt signaling pathway Additionally musk ketone has been observed to confer neuroprotective effects in stroke models by inhibiting apoptosis These characteristics make musk ketone a valuable tool for investigating mechanisms of neural injury and protection in biomedical research
Medchemexpress LLC Musk ketone | 81-14-1 | 294.31 | 1 ML
Musk ketone is an artificial fragrance and a cytochrome P450 enzyme inducer. It exhibits mutagenic and comutagenic effects in Hep G2 cells and promotes neural stem cell proliferation and differentiation in cerebral ischemia by activating the PI3K/Akt signaling pathway. In the brain, musk ketone provides neuroprotection against stroke injury by inhibiting cell apoptosis.
- Enhances proliferation and differentiation in neural stem cells (NSCs) with increased PI3K/Akt signaling pathway activation.
- Inhibits cell viability of GC cells and prevents colony formation.
- Induces cell cycle arrest and apoptosis in AGS and HGC-27 cells.
- Ameliorates neurological deficit and reduces infarction and cerebral ischemic injury.
- Increases CYP2B activity, protein, and mRNA levels, and boosts CYP1A enzyme activity.
Medchemexpress LLC Musk ketone | 81-14-1 | 294.31 | 100 MG
Musk ketone is a widely used artificial fragrance and a cytochrome P450 enzyme inducer. It shows mutagenic and comutagenic effects in Hep G2 cells and induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway. In the brain, musk ketone is neuroprotective against stroke injury through inhibition of cell apoptosis. It also inhibits the cell viability of GC cells and induces cell cycle arrest and apoptosis.
- Enhances proliferation and differentiation in neural stem cells
- Increases PI3K/Akt signaling pathway activation
- Ameliorates neurological deficit and reduces infarction and cerebral ischemic injury
- Increases CYP2B activity, protein and mRNA levels, and increases CYP1A enzyme activity