Phenols
eMolecules 636-00-0 | 6-HYDROXYDOPAMINE HBR | AstaTech | MFCD00012894 | 250.092 | C8H12BrNO3 | 95.000 | Br.NCCc1cc(O)c(O)cc1O | 1g | 273167976
6-HYDROXYDOPAMINE HBR | AstaTech | 636-00-0 | MFCD00012894 | 250.092 | C8H12BrNO3 | 95.000 | Br.NCCc1cc(O)c(O)cc1O | 1g | 273167976
Apexbio Technology LLC HyperTrap SP HP Column 1ml
HyperTrap SP HP Column is a chromatography medium designed for the efficient purification of biomolecules based on strong cation exchange principles The column utilizes sulfopropyl (SP) ligands immobilized on a high-performance matrix allowing selective binding of positively charged proteins and peptides under controlled buffer conditions This mechanism facilitates the separation and enrichment of target analytes from complex biological samples The HyperTrap SP HP Column is commonly applied in protein purification workflows biomarker discovery and quality control assays within biomedical research
Medchemexpress LLC N-Bis(2-hydroxypropyl)nitrosamine | 53609-64-6 | 98.0% | 162.19 | 100 MG
N-Bis(2-hydroxypropyl)nitrosamine is a tumor model inducing agent and a metabolite of di-n-propylnitrosamine (DPN). It is an agent with carcinogenic activity and can be used to construct pancreatic cancer models. This product is for research use only.
- Tumor model inducing agent
- Metabolite of di-n-propylnitrosamine (DPN)
- Carcinogenic activity
- Used to construct pancreatic cancer models
Medchemexpress LLC Sefaxersen sodium | 2272983-11-4 | 99.5% | 8678.96 (free acid) | 1 MG
Sefaxersen sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). It effectively reduces circulating levels of CFB and can be used for geographic atrophy (GA) research.
- Specific antisense oligonucleotide (ASO)
- Targets complement factor B (CFB)
- Reduces circulating levels of CFB
- Used for geographic atrophy (GA) research
eMolecules 116435-77-9 | 2-Amino-3-bromophenol | Combi-Blocks | MFCD08445676 | 188.024 | C6H6BrNO | 98.000 | Nc1c(O)cccc1Br | 5g | 232314114
2-Amino-3-bromophenol | Combi-Blocks | 116435-77-9 | MFCD08445676 | 188.024 | C6H6BrNO | 98.000 | Nc1c(O)cccc1Br | 5g | 232314114
eMolecules 196081-71-7 | 2-Bromo-3-hydroxybenzaldehyde | Apollo Scientific US - Building Blocks | MFCD00092081 | 201.019 | C7H5BrO2 | 98.000 | Oc1cccc(C=O)c1Br | 25g | 455280892
2-Bromo-3-hydroxybenzaldehyde | Apollo Scientific US - Building Blocks | 196081-71-7 | MFCD00092081 | 201.019 | C7H5BrO2 | 98.000 | Oc1cccc(C=O)c1Br | 25g | 455280892
Medchemexpress LLC Pilsicainide | 88069-49-2 | MFCD00903769 | 99.9% | 308.8 g/mol | C17H25ClN2O | 50 MG
Pilsicainide hydrochloride is the hydrochloride salt of pilsicainide, an orally active sodium channel blocker and potent class Ic antiarrhythmic agent. It is supplied for research use in electrophysiology and cardiac pharmacology to investigate sodium channel modulation and arrhythmia mechanisms.
- Orally active sodium channel blocker
- Class Ic antiarrhythmic agent
- Hydrochloride salt form for improved solubility
- Reported purity approximately 99.9% for research use
- Used in electrophysiology and cardiac pharmacology studies
- Provided in small laboratory quantities for experimental work
Medchemexpress LLC Menin-MLL inhibitor MI-2 | 1271738-62-5 | C18H25N5S2 | 1 ML
Menin-MLL inhibitor MI-2 is a competitive and selective Menin-MLL interaction inhibitor. It effectively downregulates target genes like HOXA9 and MEIS1, leading to inhibition of leukemia cell proliferation and induction of apoptosis and differentiation. This compound shows promise in the research of MLL-rearranged acute leukemias, including AML and ALL, with an IC50 of 446 nM and a Ki value of 158 nM.
- Competitive and selective Menin-MLL interaction inhibitor
- Downregulates expression of target genes (HOXA9, MEIS1)
- Inhibits proliferation of leukemia cells
- Induces apoptosis and differentiation
- Promising for research of MLL-rearranged acute leukemias
Medchemexpress LLC P-CAB agent 2 (hydrochloride) | 2209911-80-6 | C22H26ClFN2O4S | 50 MG
P-CAB agent 2 hydrochloride is a potent and orally active potassium-competitive acid blocker and a gastric acid secretion inhibitor. It inhibits H+/K+-ATPase activity with an IC50 value of <100 nM and the hERG potassium channel with an IC50 value of 18.69 μM. This compound shows no acute toxicity and inhibits histamine-induced gastric acid secretion.
- Potent and orally active potassium-competitive acid blocker
- Gastric acid secretion inhibitor
- Inhibits H+/K+-ATPase activity with an IC50 value of <100 nM
- Inhibits hERG potassium channel with an IC50 value of 18.69 μM
- Shows no acute toxicity
- Inhibits histamine-induced gastric acid secretion
Medchemexpress LLC SPOP-IN-6b dihydrochloride | 99.7% | 573.51 | 25 MG
SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM. SPOP-IN-6b dihydrochloride shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells. SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content.
- Potent speckle-type POZ protein (SPOP) inhibitor with an IC50 of 3.58 μM.
- Shows IC50s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells.
- Can suppress SPOP activity and increase suppression cancer substrate protein PTEN and DUSP7 content.
- In vivo, it can slow down the growth of tumor by suppressing SPOP.