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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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NGM-313 is a CHO-expressed human antibody targeting Klotho Beta NGM-313 contains a huIgG1 heavy chain and a hu light chain with a predicted molecular weight (MW) of 150 kDa The isotype control for NGM-313 can refer to Human IgG1 kappa Isotype Control (HY-P99001)
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h/m KRT10-sh-RFP-BSD shRNA lentiviral vector expressing RFP with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m keratin 10 (KRT10) shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse keratin 10 (KRT10) The shRNA has been validated to meet or exceed 70% KRT10 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5 HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells HODHBt can be used for research of HIV-infection and cancer[1]
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